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. 1994 Dec;47(12):1118–1119. doi: 10.1136/jcp.47.12.1118

False positive immunoreaction in products of conception.

F G Barker 1, P Ozua 1, S Van Noorden 1
PMCID: PMC502207  PMID: 7876388

Abstract

False positive immunostaining for cytomegalovirus in products of conception was revealed using an avidinbiotinylated peroxidase complex. The cause was shown to be endogenous biotin. The use of a non-avidin-biotin method avoided the problem.

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Selected References

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  1. Yokoyama S., Kashima K., Inoue S., Daa T., Nakayama I., Moriuchi A. Biotin-containing intranuclear inclusions in endometrial glands during gestation and puerperium. Am J Clin Pathol. 1993 Jan;99(1):13–17. doi: 10.1093/ajcp/99.1.13. [DOI] [PubMed] [Google Scholar]

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