Abstract
A study was made of the contribution of the cytobrush to determining the composition of the cervical smear. From a population of women screened in The Netherlands in 1987, 733 women were selected whose smears for the second time in a row lacked endocervical cells. Note was made of method of contraception, age of the woman, and day of the menstrual cycle. A control group was formed of women whose smears contained endocervical cells. Highly significant differences were found in the results between the two groups. Two new samples were collected, one made with the modified wooden Ayre spatula, the other with the cytobrush from the research group. The number of smears containing endocervical cells increased from 44% (by spatula alone) to 79% (spatula plus cytobrush). The cytobrush alone produced a high percentage of unsatisfactory smears (17.5%) due to a low content of squamous epithelial cells. No differences could be observed in the rate of cellular atypia because of the small number of cases.
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Selected References
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- Boon M. E., Alons-van Kordelaar J. J., Rietveld-Scheffers P. E. Consequences of the introduction of combined spatula and Cytobrush sampling for cervical cytology. Improvements in smear quality and detection rates. Acta Cytol. 1986 May-Jun;30(3):264–270. [PubMed] [Google Scholar]
- Bourne R., Beilby J. O. Trial of new cervical spatula. Lancet. 1976 Jun 19;1(7973):1330–1331. doi: 10.1016/s0140-6736(76)92659-3. [DOI] [PubMed] [Google Scholar]
- Elias A., Linthorst G., Bekker B., Vooijs P. G. The significance of endocervical cells in the diagnosis of cervical epithelial changes. Acta Cytol. 1983 May-Jun;27(3):225–229. [PubMed] [Google Scholar]
- Kivlahan C., Ingram E. Papanicolaou smears without endocervical cells. Are they inadequate? Acta Cytol. 1986 May-Jun;30(3):258–260. [PubMed] [Google Scholar]
- Reissman S. E. Comparison of two Papanicolaou smear techniques in a family practice setting. J Fam Pract. 1988 May;26(5):525–529. [PubMed] [Google Scholar]
- Rombach J. J., Cranendonk R., Velthuis F. J. Monitoring laboratory performance by statistical analysis of rescreening cervical smears. Acta Cytol. 1987 Nov-Dec;31(6):887–894. [PubMed] [Google Scholar]
- Stock R. J., Thurmond A. I., Passmore A. A comparison between the Accu-Pap device and the extended-tip wooden Ayre spatula for cervical cytology sampling. Acta Cytol. 1988 May-Jun;32(3):307–310. [PubMed] [Google Scholar]
- Taylor P. T., Jr, Andersen W. A., Barber S. R., Covell J. L., Smith E. B., Underwood P. B., Jr The screening Papanicolaou smear: contribution of the endocervical brush. Obstet Gynecol. 1987 Nov;70(5):734–738. [PubMed] [Google Scholar]
- Trimbos J. B., Arentz N. P. The efficiency of the Cytobrush versus the cotton swab in the collection of endocervical cells in cervical smears. Acta Cytol. 1986 May-Jun;30(3):261–263. [PubMed] [Google Scholar]
- Vooijs G. P., van der Graaf Y., Elias A. G. Cellular composition of cervical smears in relation to the day of the menstrual cycle and the method of contraception. Acta Cytol. 1987 Jul-Aug;31(4):417–426. [PubMed] [Google Scholar]
- Vooijs P. G., Elias A., van der Graaf Y., Veling S. Relationship between the diagnosis of epithelial abnormalities and the composition of cervical smears. Acta Cytol. 1985 May-Jun;29(3):323–328. [PubMed] [Google Scholar]
- van der Graaf Y., Vooijs G. P., Gaillard H. L., Go D. M. Screening errors in cervical cytologic screening. Acta Cytol. 1987 Jul-Aug;31(4):434–438. [PubMed] [Google Scholar]