Abstract
AIM--To determine whether sampling the anterior and posterior cervical lips in hysterectomy specimens provides the best opportunity for detecting unsuspected cervical intraepithelial neoplasia (CIN). METHODS--The frequency with which CIN was identified at a range of positions on the anterior and posterior lips and left and right lateral aspects of the cervix was assessed in 100 cone biopsy specimens. RESULTS--CIN affected one or other cervical lip in all 100 cases studied and involved the midline positions (12 and 6 o'clock) in 94. The lateral edges of the cervical canal were also involved in 38 cases. CONCLUSION--CIN is more likely to be identified on the anterior and posterior lips than on the lateral aspect of the cervical os. The findings support the continuation of the established practice of taking blocks from the midline in these areas.
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Selected References
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- Anderson M. C., Brown C. L., Buckley C. H., Fox H., Jenkins D., Lowe D. G., Manners B. T., Melcher D. H., Robertson A. J., Wells M. Current views on cervical intraepithelial neoplasia. J Clin Pathol. 1991 Dec;44(12):969–978. doi: 10.1136/jcp.44.12.969. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Hall P. A., Lane D. P. p53 in tumour pathology: can we trust immunohistochemistry?--Revisited! J Pathol. 1994 Jan;172(1):1–4. doi: 10.1002/path.1711720103. [DOI] [PubMed] [Google Scholar]
- Ng A. B., Reagan J. W. Microinvasive carcinoma of the uterine cervix. Am J Clin Pathol. 1969 Nov;52(5):511–529. doi: 10.1093/ajcp/52.5.511. [DOI] [PubMed] [Google Scholar]
- PRZYBORA L. A., PLUTOWA A. Histological topography of carcinoma in situ of the cervix uteri. Cancer. 1959 Mar-Apr;12(2):263–277. doi: 10.1002/1097-0142(195903/04)12:2<263::aid-cncr2820120210>3.0.co;2-r. [DOI] [PubMed] [Google Scholar]
- RICHART R. M. COLPOMICROSCOPIC STUDIES OF THE DISTRIBUTION OF DYSPLASIA AND CARCINOMA IN SITU ON THE EXPOSED PORTION OF THE HUMAN UTERINE CERVIX. Cancer. 1965 Aug;18:950–954. doi: 10.1002/1097-0142(196508)18:8<950::aid-cncr2820180805>3.0.co;2-t. [DOI] [PubMed] [Google Scholar]
- Scurry J., Patel K., Wells M. ACP Broadsheet No 138: May 1993. Gross examination of uterine specimens. J Clin Pathol. 1993 May;46(5):388–393. doi: 10.1136/jcp.46.5.388. [DOI] [PMC free article] [PubMed] [Google Scholar]
