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. 1992 Nov 1;89(21):10129–10133. doi: 10.1073/pnas.89.21.10129

Immobilization of DNA for scanning probe microscopy.

D P Allison 1, L A Bottomley 1, T Thundat 1, G M Brown 1, R P Woychik 1, J J Schrick 1, K B Jacobson 1, R J Warmack 1
PMCID: PMC50291  PMID: 1438201

Abstract

Reproducible scanning tunneling microscope and atomic force microscope images of entire molecules of uncoated plasmid DNA chemically bound to surfaces are presented. The chemically mediated immobilization of DNA to surfaces and subsequent scanning tunneling microscope imaging of DNA molecules demonstrate that the problem of molecular instability to forces exerted by the probe tip, inherent with scanning probe microscopes, can be prevented.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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