Table 2.
Induction of mucosal IL-17/IL-22 is Batf3-independent after oral C. albicans infection.
| Cytokine/Chemokine | Batf3+/+ | Batf3−/− | P-value |
|---|---|---|---|
| IL-1β | 8500 ± 3137 | 9773 ± 2616 | 0.3874 |
| IL-4 | 1380 ± 208.1 | 985.7 ± 81.49 | 0.1078 |
| IL-6 | 22112 ± 5407 | 22190 ± 3522 | 0.4740 |
| IL-10 | 1755 ± 225.5 | 1166 ± 95.44 | 0.0370* |
| IL-17A | 298.0 ± 48.83 | 270.4 ± 20.97 | 0.6145 |
| IL-22 | 312.6 ± 162.1 | 304.3 ± 112.1 | >0.9999 |
| CCL2 | 52548 ± 18743 | 61327 ± 14405 | 0.3874 |
| CCL3 | 632.4 ± 359.8 | 989.4 ± 455.6 | 0.3052 |
| CCL4 | 286.3 ± 175.2 | 888.0 ± 423.8 | 0.1320 |
| CCL5 | 139.5 ± 33.43 | 197.6 ± 59.90 | 0.4166 |
| CXCL1 | 6557 ± 3242 | 5361 ± 1599 | 0.7476 |
| CXCL2 | 9158 ± 4423 | 10430 ± 3757 | 0.8308 |
Notes. Cytokine and chemokine concentrations are expressed as pg/g of tongue at day 1 post-infection. Data represent mean values ± SEM and are combined from 2 independent experiments with a total n of 6 mice/group. Statistical analysis was performed using an unpaired t-test or Mann-Whitney U test, where appropriate. An * indicates that the values are significantly different from one another.