Skip to main content
NCBI home page
Journal of Clinical Pathology logoLink to Journal of Clinical Pathology
. 1995 Nov;48(11):984–989. doi: 10.1136/jcp.48.11.984

The age related amyloids: a growing family of unique biochemical substances.

G G Cornwell 3rd 1, K H Johnson 1, P Westermark 1
PMCID: PMC502998  PMID: 8543642

Full text

PDF
984

Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. Betsholtz C., Svensson V., Rorsman F., Engström U., Westermark G. T., Wilander E., Johnson K., Westermark P. Islet amyloid polypeptide (IAPP):cDNA cloning and identification of an amyloidogenic region associated with the species-specific occurrence of age-related diabetes mellitus. Exp Cell Res. 1989 Aug;183(2):484–493. doi: 10.1016/0014-4827(89)90407-2. [DOI] [PubMed] [Google Scholar]
  2. Christmanson L., Betsholtz C., Gustavsson A., Johansson B., Sletten K., Westermark P. The transthyretin cDNA sequence is normal in transthyretin-derived senile systemic amyloidosis. FEBS Lett. 1991 Apr 9;281(1-2):177–180. doi: 10.1016/0014-5793(91)80387-i. [DOI] [PubMed] [Google Scholar]
  3. Cooper G. J., Willis A. C., Clark A., Turner R. C., Sim R. B., Reid K. B. Purification and characterization of a peptide from amyloid-rich pancreases of type 2 diabetic patients. Proc Natl Acad Sci U S A. 1987 Dec;84(23):8628–8632. doi: 10.1073/pnas.84.23.8628. [DOI] [PMC free article] [PubMed] [Google Scholar]
  4. Cornwell G. G., 3rd, Murdoch W. L., Kyle R. A., Westermark P., Pitkänen P. Frequency and distribution of senile cardiovascular amyloid. A clinicopathologic correlation. Am J Med. 1983 Oct;75(4):618–623. doi: 10.1016/0002-9343(83)90443-6. [DOI] [PubMed] [Google Scholar]
  5. Cornwell G. G., 3rd, Murdoch W. L., Kyle R. A., Westermark P., Pitkänen P. Frequency and distribution of senile cardiovascular amyloid. A clinicopathologic correlation. Am J Med. 1983 Oct;75(4):618–623. doi: 10.1016/0002-9343(83)90443-6. [DOI] [PubMed] [Google Scholar]
  6. Cornwell G. G., 3rd, Westermark G. T., Pitkanen P., Westermark P. Seminal vesicle amyloid: the first example of exocrine cell origin of an amyloid fibril precursor. J Pathol. 1992 Jul;167(3):297–303. doi: 10.1002/path.1711670307. [DOI] [PubMed] [Google Scholar]
  7. Eriksson L., Westermark P. Age-related accumulation of amyloid inclusions in adrenal cortical cells. Am J Pathol. 1990 Feb;136(2):461–466. [PMC free article] [PubMed] [Google Scholar]
  8. Eriksson L., Westermark P. Characterization of intracellular amyloid fibrils in the human choroid plexus epithelial cells. Acta Neuropathol. 1990;80(6):597–603. doi: 10.1007/BF00307626. [DOI] [PubMed] [Google Scholar]
  9. Eriksson L., Westermark P. Intracellular neurofibrillary tangle-like aggregations. A constantly present amyloid alteration in the aging choroid plexus. Am J Pathol. 1986 Oct;125(1):124–129. [PMC free article] [PubMed] [Google Scholar]
  10. Glenner G. G., Wong C. W. Alzheimer's disease: initial report of the purification and characterization of a novel cerebrovascular amyloid protein. Biochem Biophys Res Commun. 1984 May 16;120(3):885–890. doi: 10.1016/s0006-291x(84)80190-4. [DOI] [PubMed] [Google Scholar]
  11. Goffin Y. A., McCrickard E. L., Ameryckx J. P., Malmendier C. L., Hiden M., Cornwell G. G., 3rd Amyloidosis of the joints: evidence that human hip capsules have a unique predisposition for amyloid of the senile systemic type. Appl Pathol. 1985;3(1-2):88–95. [PubMed] [Google Scholar]
  12. Goffin Y. A., Murdoch W., Cornwell G. G., 3rd, Sorenson G. D. Microdeposits of amyloid in sclerocalcific heart valves: a histochemical and immunofluorescence study. J Clin Pathol. 1983 Dec;36(12):1342–1349. doi: 10.1136/jcp.36.12.1342. [DOI] [PMC free article] [PubMed] [Google Scholar]
  13. Golde T. E., Estus S., Younkin L. H., Selkoe D. J., Younkin S. G. Processing of the amyloid protein precursor to potentially amyloidogenic derivatives. Science. 1992 Feb 7;255(5045):728–730. doi: 10.1126/science.1738847. [DOI] [PubMed] [Google Scholar]
  14. Johansson B., Wernstedt C., Westermark P. Atrial natriuretic peptide deposited as atrial amyloid fibrils. Biochem Biophys Res Commun. 1987 Nov 13;148(3):1087–1092. doi: 10.1016/s0006-291x(87)80243-7. [DOI] [PubMed] [Google Scholar]
  15. Johansson B., Westermark P. The relation of atrial natriuretic factor to isolated atrial amyloid. Exp Mol Pathol. 1990 Jun;52(3):266–278. doi: 10.1016/0014-4800(90)90068-o. [DOI] [PubMed] [Google Scholar]
  16. Johnson K. H., O'Brien T. D., Betsholtz C., Westermark P. Islet amyloid polypeptide: mechanisms of amyloidogenesis in the pancreatic islets and potential roles in diabetes mellitus. Lab Invest. 1992 May;66(5):522–535. [PubMed] [Google Scholar]
  17. Johnson K. H., Sletten K., Hayden D. W., O'Brien T. D., Roertgen K. E., Westermark P. Pulmonary vascular amyloidosis in aged dogs. A new form of spontaneously occurring amyloidosis derived from apolipoprotein AI. Am J Pathol. 1992 Nov;141(5):1013–1019. [PMC free article] [PubMed] [Google Scholar]
  18. Kowall N. W., Beal M. F., Busciglio J., Duffy L. K., Yankner B. A. An in vivo model for the neurodegenerative effects of beta amyloid and protection by substance P. Proc Natl Acad Sci U S A. 1991 Aug 15;88(16):7247–7251. doi: 10.1073/pnas.88.16.7247. [DOI] [PMC free article] [PubMed] [Google Scholar]
  19. Linke R. P., Voigt C., Störkel F. S., Eulitz M. N-terminal amino acid sequence analysis indicates that isolated atrial amyloid is derived from atrial natriuretic peptide. Virchows Arch B Cell Pathol Incl Mol Pathol. 1988;55(2):125–127. doi: 10.1007/BF02896569. [DOI] [PubMed] [Google Scholar]
  20. Looi L. M. Isolated atrial amyloidosis: a clinicopathologic study indicating increased prevalence in chronic heart disease. Hum Pathol. 1993 Jun;24(6):602–607. doi: 10.1016/0046-8177(93)90239-d. [DOI] [PubMed] [Google Scholar]
  21. Masters C. L., Simms G., Weinman N. A., Multhaup G., McDonald B. L., Beyreuther K. Amyloid plaque core protein in Alzheimer disease and Down syndrome. Proc Natl Acad Sci U S A. 1985 Jun;82(12):4245–4249. doi: 10.1073/pnas.82.12.4245. [DOI] [PMC free article] [PubMed] [Google Scholar]
  22. Mucchiano G., Cornwell G. G., 3rd, Westermark P. Senile aortic amyloid. Evidence for two distinct forms of localized deposits. Am J Pathol. 1992 Apr;140(4):871–877. [PMC free article] [PubMed] [Google Scholar]
  23. Mullan M., Crawford F. Genetic and molecular advances in Alzheimer's disease. Trends Neurosci. 1993 Oct;16(10):398–403. doi: 10.1016/0166-2236(93)90007-9. [DOI] [PubMed] [Google Scholar]
  24. Pitkänen P., Westermark P., Cornwell G. G., 3rd, Murdoch W. Amyloid of the seminal vesicles. A distinctive and common localized form of senile amyloidosis. Am J Pathol. 1983 Jan;110(1):64–69. [PMC free article] [PubMed] [Google Scholar]
  25. Pitkänen P., Westermark P., Cornwell G. G., 3rd Senile systemic amyloidosis. Am J Pathol. 1984 Dec;117(3):391–399. [PMC free article] [PubMed] [Google Scholar]
  26. Sanke T., Bell G. I., Sample C., Rubenstein A. H., Steiner D. F. An islet amyloid peptide is derived from an 89-amino acid precursor by proteolytic processing. J Biol Chem. 1988 Nov 25;263(33):17243–17246. [PubMed] [Google Scholar]
  27. Selkoe D. J. Alzheimer's disease: a central role for amyloid. J Neuropathol Exp Neurol. 1994 Sep;53(5):438–447. doi: 10.1097/00005072-199409000-00003. [DOI] [PubMed] [Google Scholar]
  28. Selkoe D. J. Physiological production of the beta-amyloid protein and the mechanism of Alzheimer's disease. Trends Neurosci. 1993 Oct;16(10):403–409. doi: 10.1016/0166-2236(93)90008-a. [DOI] [PubMed] [Google Scholar]
  29. Sletten K., Westermark P., Natvig J. B. Characterization of amyloid fibril proteins from medullary carcinoma of the thyroid. J Exp Med. 1976 Apr 1;143(4):993–998. doi: 10.1084/jem.143.4.993. [DOI] [PMC free article] [PubMed] [Google Scholar]
  30. Sletten K., Westermark P., Natvig J. B. Senile cardiac amyloid is related to prealbumin. Scand J Immunol. 1980;12(6):503–506. doi: 10.1111/j.1365-3083.1980.tb00098.x. [DOI] [PubMed] [Google Scholar]
  31. Tashima T., Kitamoto T., Tateishi J., Ogomori K., Nakagaki H. Incidence and characterization of age related amyloid deposits in the human anterior pituitary gland. Virchows Arch A Pathol Anat Histopathol. 1988;412(4):323–327. doi: 10.1007/BF00750258. [DOI] [PubMed] [Google Scholar]
  32. Westermark G. T., Christmanson L., Terenghi G., Permerth J., Betsholtz C., Larsson J., Polak J. M., Westermark P. Islet amyloid polypeptide: demonstration of mRNA in human pancreatic islets by in situ hybridization in islets with and without amyloid deposits. Diabetologia. 1993 Apr;36(4):323–328. doi: 10.1007/BF00400235. [DOI] [PubMed] [Google Scholar]
  33. Westermark P., Engström U., Johnson K. H., Westermark G. T., Betsholtz C. Islet amyloid polypeptide: pinpointing amino acid residues linked to amyloid fibril formation. Proc Natl Acad Sci U S A. 1990 Jul;87(13):5036–5040. doi: 10.1073/pnas.87.13.5036. [DOI] [PMC free article] [PubMed] [Google Scholar]
  34. Westermark P., Johansson B., Natvig J. B. Senile cardiac amyloidosis: evidence of two different amyloid substances in the ageing heart. Scand J Immunol. 1979;10(4):303–308. doi: 10.1111/j.1365-3083.1979.tb01355.x. [DOI] [PubMed] [Google Scholar]
  35. Westermark P., Johnson K. H., O'Brien T. D., Betsholtz C. Islet amyloid polypeptide--a novel controversy in diabetes research. Diabetologia. 1992 Apr;35(4):297–303. doi: 10.1007/BF00401195. [DOI] [PubMed] [Google Scholar]
  36. Westermark P., Sletten K., Johansson B., Cornwell G. G., 3rd Fibril in senile systemic amyloidosis is derived from normal transthyretin. Proc Natl Acad Sci U S A. 1990 Apr;87(7):2843–2845. doi: 10.1073/pnas.87.7.2843. [DOI] [PMC free article] [PubMed] [Google Scholar]
  37. Westermark P., Wernstedt C., Wilander E., Hayden D. W., O'Brien T. D., Johnson K. H. Amyloid fibrils in human insulinoma and islets of Langerhans of the diabetic cat are derived from a neuropeptide-like protein also present in normal islet cells. Proc Natl Acad Sci U S A. 1987 Jun;84(11):3881–3885. doi: 10.1073/pnas.84.11.3881. [DOI] [PMC free article] [PubMed] [Google Scholar]
  38. Westermark P., Wernstedt C., Wilander E., Sletten K. A novel peptide in the calcitonin gene related peptide family as an amyloid fibril protein in the endocrine pancreas. Biochem Biophys Res Commun. 1986 Nov 14;140(3):827–831. doi: 10.1016/0006-291x(86)90708-4. [DOI] [PubMed] [Google Scholar]
  39. Yankner B. A., Mesulam M. M. Seminars in medicine of the Beth Israel Hospital, Boston. beta-Amyloid and the pathogenesis of Alzheimer's disease. N Engl J Med. 1991 Dec 26;325(26):1849–1857. doi: 10.1056/NEJM199112263252605. [DOI] [PubMed] [Google Scholar]

Articles from Journal of Clinical Pathology are provided here courtesy of BMJ Publishing Group

RESOURCES