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. 2016 Sep 20;4:e2483. doi: 10.7717/peerj.2483

Table 5. Neonatal outcome—morbidity.

Conservative (n = 77) missing Aggressive (n = 85) missing P
Hospitalization, days 77 [61–98]b 78 [58–100]b 0.710
Death 9 (11.7)a 11 (13.0)a 1.000
PNAC 35 (45.5)a 23 (27.0)a 0.021
Onset (day of life) 34 [20–45]b 30 [12–39] b 0.460
Peak conjugated bilirubin 5.0 [3.2–8.4]b 4.7 [3.3–7.4]b 0.851
Mortality 8/35 (22.9)a 5/23 (21.7)a 1.000
Sepsis (culture proven) 36 (46.7)a 25 (29.4)a 0.024
Necrotizing enterocolitis 8 (10.4)a 8 (9.4)a 1.000
Focal intestinal perforation 1 (1.3)a 1 (1.2)a 0.726
IVH grade 3/4 14 (18.1)a 10 (11.8)a 0.275
Surgery (any) 26 (33.8)a 35 (41.2)a 0.209
Surgery (GI) 11 (14.3)a 8 (9.4)a 0.464
NEC and/or GI surgery 12 (15.6)a 11 (12.9)a 0.658
Cystic PVL 3 (3.9)a 1 (1.2)a 0.274
BPD 19 (24.6)a 16 (20.7)a 24 (28.2)a 23 (27.0)a 0.451
Steroids for BPD 16 (20.8)a 10 (11.8)a 0.137
Medical treatment for PDA 44 (57.1)a 59 (69.4)a 0.141
ROP (any stage) 18 (23.3)a 8 (10.4)a 27 (31.8)a 11 (12.9)a 0.209

Notes.

Univariate analysis of neonatal outcome parameters. Categorical data were tested using the Chi Square test; metric data were tested using the student’s t test.

P values < 0.05 were considered statistically significant and printed in bold letters.

a

number with percentage in parentheses.

b

median and interquartile range.

PNAC
parenteral nutrition associated cholestasis
IVH
intraventricular hemorrhage
PVL
periventricular leucomalacia
BPD
bronchopulmonary dysplasia
PDA
persistent ductus arteriosus
ROP
retinopathy of prematurity
GI
gastrointestinal