Table 5. Neonatal outcome—morbidity.
Conservative (n = 77) | missing | Aggressive (n = 85) | missing | P | |
---|---|---|---|---|---|
Hospitalization, days | 77 [61–98]b | 78 [58–100]b | 0.710 | ||
Death | 9 (11.7)a | 11 (13.0)a | 1.000 | ||
PNAC | 35 (45.5)a | 23 (27.0)a | 0.021 | ||
Onset (day of life) | 34 [20–45]b | 30 [12–39] b | 0.460 | ||
Peak conjugated bilirubin | 5.0 [3.2–8.4]b | 4.7 [3.3–7.4]b | 0.851 | ||
Mortality | 8/35 (22.9)a | 5/23 (21.7)a | 1.000 | ||
Sepsis (culture proven) | 36 (46.7)a | 25 (29.4)a | 0.024 | ||
Necrotizing enterocolitis | 8 (10.4)a | 8 (9.4)a | 1.000 | ||
Focal intestinal perforation | 1 (1.3)a | 1 (1.2)a | 0.726 | ||
IVH grade 3/4 | 14 (18.1)a | 10 (11.8)a | 0.275 | ||
Surgery (any) | 26 (33.8)a | 35 (41.2)a | 0.209 | ||
Surgery (GI) | 11 (14.3)a | 8 (9.4)a | 0.464 | ||
NEC and/or GI surgery | 12 (15.6)a | 11 (12.9)a | 0.658 | ||
Cystic PVL | 3 (3.9)a | 1 (1.2)a | 0.274 | ||
BPD | 19 (24.6)a | 16 (20.7)a | 24 (28.2)a | 23 (27.0)a | 0.451 |
Steroids for BPD | 16 (20.8)a | 10 (11.8)a | 0.137 | ||
Medical treatment for PDA | 44 (57.1)a | 59 (69.4)a | 0.141 | ||
ROP (any stage) | 18 (23.3)a | 8 (10.4)a | 27 (31.8)a | 11 (12.9)a | 0.209 |
Notes.
Univariate analysis of neonatal outcome parameters. Categorical data were tested using the Chi Square test; metric data were tested using the student’s t test.
P values < 0.05 were considered statistically significant and printed in bold letters.
number with percentage in parentheses.
median and interquartile range.
- PNAC
- parenteral nutrition associated cholestasis
- IVH
- intraventricular hemorrhage
- PVL
- periventricular leucomalacia
- BPD
- bronchopulmonary dysplasia
- PDA
- persistent ductus arteriosus
- ROP
- retinopathy of prematurity
- GI
- gastrointestinal