Figure 1.

Schematic representation of the mechanism of an evaporative light scattering detector (ELSD). First, the chromatographic eluate passes through the nebulizer and mixes with the nebulizing gas (N₂), causing dispersion of droplets; subsequently, droplets enter into the nebulizing chamber where the mobile phase evaporates and condenses, being removed as waste; Finally, the analyte crosses an optical cell, a laser beam penetrates the particles, and the scattered light is detected and converted into a signal.