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. Author manuscript; available in PMC: 2016 Sep 28.
Published in final edited form as: Science. 2016 Sep 9;353(6304):1144–1147. doi: 10.1126/science.aaf8713

Fig. 1. A dramatic shift in chemoselectivity arises with different aminating agents.

Fig. 1

o-Allylanisole (1) undergoes chemoselective olefin aziridination in the presence of catalytic Rh2(esp)2 (6) and aminating agent DPH (2) in 2,2,2-trifluoroethanol (TFE = CF3CH2OH) to give 3. Changing the aminating agent to TsONHMe (4a) furnishes the corresponding N-Me aniline (5).