Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2016 Jul 15;5(3):32. doi: 10.3390/cells5030032

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© 2016 by the authors; licensee MDPI, Basel, Switzerland.

This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC-BY) license (http://creativecommons.org/licenses/by/4.0/).

PMC Copyright notice

Mutation of the intestinal filament organizer IFO-1 leads to a collapse of the intermediate filament network onto the C. elegans apical junction (CeAJ). (A) The confocal fluorescence micrographs (projection views) show the distribution of the fluorescent transgene product IFB-2: CFP in a wild type background (wt; strain BJ49; see [58]); Note the exclusive fluorescence in the intestine (anterior to the right upper corner; overlay image with Nomarski optics in (A')); IFB-2: CFP is concentrated in the evenly shaped endotube (arrows), which demarcates the ovoid intestinal lumen; (B) shows the distribution of IFB-2: CFP in ifo-1 mutant strain BJ133 (mt; [58]); Note that the intermediate filament network of the endotube has collapsed completely into aggregates decorating the C. elegans apical junction (fine lines marked by arrowheads) and formed cytoplasmatic granules (arrows). Overlay image with Nomarski optics in (B'). Scale bars = 50 μm.