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. 1991 Jan;75(1):45–48. doi: 10.1136/bjo.75.1.45

Pupil cycle time and early autonomic involvement in ocular leprosy.

M A Karaçorlu 1, Z Sürel 1, T Cakiner 1, E Hanyaloğlu 1, T Saylan 1, C Mat 1
PMCID: PMC504106  PMID: 1991087

Abstract

Ocular complications of leprosy patients often develop insidiously and with few if any symptoms. This study involves measurement of the pupil cycle time (PCT) to evaluate the autonomic nerve system of the iris to determine the presence of subclinical intraocular involvement. The study included 19 lepromatous (LL), 19 borderline lepromatous (BL), and five borderline tuberculoid (BT) leprosy patients and involved 25 healthy volunteers, 10 patients with pulmonary tuberculosis and eight with Duhring disease. The PCT was measured in these groups. In all leprosy groups included in the study the PCT was higher than in the control groups. Moreover, the PCT of the leprosy patients without any intraocular involvement was higher than in the controls. These results show that in the ophthalmic examination of leprosy patients without any symptoms the fact that autonomic nerve system of the eye is affected by the leprosy can often be determined by measuring the PCT.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. Binford C. H., Meyers W. M., Walsh G. P. Leprosy. JAMA. 1982 Apr 23;247(16):2283–2292. [PubMed] [Google Scholar]
  2. Campbell F. W., Whiteside T. C. Induced Pupillary Oscillations. Br J Ophthalmol. 1950 Mar;34(3):180–189. doi: 10.1136/bjo.34.3.180. [DOI] [PMC free article] [PubMed] [Google Scholar]
  3. Courtright P. D. Defining the magnitude of ocular complications from leprosy: problems of methodology. Int J Lepr Other Mycobact Dis. 1988 Dec;56(4):566–573. [PubMed] [Google Scholar]
  4. Lepore F. E., Sanborn G. E., Slevin J. T. Pupillary dysfunction in myasthenia gravis. Ann Neurol. 1979 Jul;6(1):29–33. doi: 10.1002/ana.410060107. [DOI] [PubMed] [Google Scholar]
  5. Miller S. D., Thompson H. S. Edge-light pupil cycle time. Br J Ophthalmol. 1978 Jul;62(7):495–500. doi: 10.1136/bjo.62.7.495. [DOI] [PMC free article] [PubMed] [Google Scholar]
  6. Ridley D. S., Jopling W. H. Classification of leprosy according to immunity. A five-group system. Int J Lepr Other Mycobact Dis. 1966 Jul-Sep;34(3):255–273. [PubMed] [Google Scholar]
  7. Swift T. R., Bauschard F. D. Pupillary reactions in lepromatous leprosy. Int J Lepr Other Mycobact Dis. 1972 Apr-Jun;40(2):142–148. [PubMed] [Google Scholar]

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