Abstract
Following extracapsular cataract and posterior chamber implant surgery the sequential recovery of the blood-aqueous barrier was measured by anterior segment fluorophotometry. Postoperatively 49 (69.0%) out of 71 eyes (71 patients) had recovered at a uniform rate, re-establishing a normal blood-aqueous barrier by the end of the three-month study. In these eyes recovery of the blood-aqueous barrier was unaffected by the use of preoperative indomethacin, the surgeon, the type of section, or the type of fixation of the implant. In eyes recovering normally after cataract surgery the rate of recovery of the blood-aqueous barrier can be expressed by a in the equation a = (y-b)/x, in which y is the logarithm of the anterior chamber fluorescence, x is the time after surgery, and b is a constant for each patient which is the anterior chamber fluorescence measured immediately after surgery. This normal rate of recovery provides a baseline from which to assess surgical technique or postoperative medication.
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Selected References
These references are in PubMed. This may not be the complete list of references from this article.
- Apple D. J., Craythorn J. M., Olson R. J., Little L. E., Lyman J. B., Reidy J. J., Loftfield K. Anterior segment complications and neovascular glaucoma following implantation of a posterior chamber intraocular lens. Ophthalmology. 1984 Apr;91(4):403–419. doi: 10.1016/s0161-6420(84)34290-7. [DOI] [PubMed] [Google Scholar]
- Champion R., McDonnell P. J., Green W. R. Intraocular lenses. Histopathologic characteristics of a large series of autopsy eyes. Surv Ophthalmol. 1985 Jul-Aug;30(1):1–32. doi: 10.1016/0039-6257(85)90085-2. [DOI] [PubMed] [Google Scholar]
- Easty D., Dallas N., O'Malley R. Aphakic macular oedema following prosthetic lens implantation. Br J Ophthalmol. 1977 May;61(5):321–326. doi: 10.1136/bjo.61.5.321. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Liesegang T. J., Bourne W. M., Brubaker R. F. The effect of cataract surgery on the blood--aqueous barrier. Ophthalmology. 1984 Apr;91(4):399–402. doi: 10.1016/s0161-6420(84)34276-2. [DOI] [PubMed] [Google Scholar]
- McDonnell P. J., Green W. R., Maumenee A. E., Iliff W. J. Pathology of intraocular lenses in 33 eyes examined postmortem. Ophthalmology. 1983 Apr;90(4):386–403. doi: 10.1016/s0161-6420(83)34558-9. [DOI] [PubMed] [Google Scholar]
- Menerath J. M., Coulangeon L. M., al-Odeh A. Evaluation fluorophotométrique des barrières hémato-oculaires dans la chirurgie de la cataracte. Ophtalmologie. 1988 Jan-Mar;2(1):37–40. [PubMed] [Google Scholar]
- Miyake K., Asakura M., Kobayashi H. Effect of intraocular lens fixation on the blood-aqueous barrier. Am J Ophthalmol. 1984 Oct 15;98(4):451–455. doi: 10.1016/0002-9394(84)90130-2. [DOI] [PubMed] [Google Scholar]
- Miyake K., Asakura M., Maekubo K. Consensual reactions of human blood-aqueous barrier to implant operations. Arch Ophthalmol. 1984 Apr;102(4):558–561. doi: 10.1001/archopht.1984.01040030436020. [DOI] [PubMed] [Google Scholar]
- Miyake K. Fluorophotometric evaluation of the blood-ocular barrier function following cataract surgery and intraocular lens implantation. J Cataract Refract Surg. 1988 Sep;14(5):560–568. doi: 10.1016/s0886-3350(88)80016-6. [DOI] [PubMed] [Google Scholar]
- Sanders D. R., Kraff M. C., Lieberman H. L., Peyman G. A., Tarabishy S. Breakdown and reestablishment of blood-aqueous barrier with implant surgery. Arch Ophthalmol. 1982 Apr;100(4):588–590. doi: 10.1001/archopht.1982.01030030590007. [DOI] [PubMed] [Google Scholar]
- Sanders D. R., Kraff M. Steroidal and nonsteroidal anti-inflammatory agents. Effect on postsurgical inflammation and blood-aqueous humor barrier breakdown. Arch Ophthalmol. 1984 Oct;102(10):1453–1456. doi: 10.1001/archopht.1984.01040031173012. [DOI] [PubMed] [Google Scholar]
- Sawa M., Sakanishi Y., Okuno Y., Shimizu H. Posterior chamber lens implantation and anterior segment barrier function: a fluorophotometric study. Jpn J Ophthalmol. 1988;32(3):297–303. [PubMed] [Google Scholar]