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. 1992 Feb;76(2):91–94. doi: 10.1136/bjo.76.2.91

Improved iodine-125 plaque design in the treatment of choroidal malignant melanoma.

J C Hill 1, R Sealy 1, D Shackleton 1, C Stannard 1, J Korrubel 1, E Hering 1, C Loxton 1
PMCID: PMC504169  PMID: 1739723

Abstract

The use and development of iodine-125 plaque therapy for choroidal malignant melanoma are described. Since 1975 experience has led to changes in plaque design and insertion techniques. Twenty-one patients were irradiated with local episcleral iodine-125 plaques. Three patients required a second plaque for tumour recurrence. Four eyes were enucleated because of continued tumour growth and a further eye was removed because of glaucoma secondary to radiation retinopathy. Two patients (9.5%) died of metastases. The remaining 19 patients are alive and clinically clear of metastases, with a mean follow up time of 73.1 months (range 43-142 months).

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Selected References

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