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. 2016 Mar 21;7(18):25593–25603. doi: 10.18632/oncotarget.8232

Figure 4. Changes in SPCA-1cell invasion capacity in the 3D microfluidic device.

Figure 4

A. Representative images of the effect of control IMDM and WI38-conditioned and co-culture-conditioned growth media on SPCA-1cell migration at different time points. Arrows indicated invading tumor cells. B. Quantitative data showed the distance of cell invasion and the number of invading cells under the different treatment conditions at 48h. Data are plotted as mean ± SD of three separate experiments. ***P < 0.001 versus IMDM medium control; ###P < 0.001 versus WI38 secretion control, and &&&P < 0.001 versus co-culture medium control.