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. 2016 Apr 8;7(18):26806–26822. doi: 10.18632/oncotarget.8645

Table 1. Multivariate analysis with Cox proportional hazards model for overall survival.

Factor Total cases (n = 122)
Univariate analysis Multivariate analysis
Risk ratio label (95% confidence interval) P Risk ratio label (95% confidence interval) P
MMP10 high (score 2) 3.30 (1.67–6.51) 0.001** 2.39 (1.19–4.80) 0.014*
Advanced age (over 50) 1.78 (0.82–3.87) 0.14
Multipara ( 2) 1.78 (0.70–3.24) 0.12
Histological subtype
 Serous 1.55 (0.82–2.92) 0.17
 Cleacell 0.81 (0.40–1.63) 0.55
 Endometrioid 0.50 (0.16–1.64) 0.26
 Mucinous 0.97 (0.23–4.02) 0.97
Advanced Stage (over FIGO Stage III) 8.02 (2.85–22.59) < 0.001**
 Peritoneal dissemination 4.73 (1.93–9.90) < 0.001**
 Lymph node metastasis 1.48 (0.78–2.81) 0.23
 Platinum resistant 12.46 (5.18–29.96) < 0.001** 5.75 (2.09–15.81) 0.001**
 Nonoptimal debulking surgery 7.00 (3.33–14.74) < 0.001** 2.84 (1.21–6.64) 0.016*
Factor Advanced cases (n = 74)
Univariate analysis Multivariate analysis
Risk ratio label (95% confidence interval) P Risk ratio label (95% confidence interval) P
MMP10 high (score 2) 2.98 (1.46–6.09) 0.003** 2.98 (1.46–6.12) 0.003**
Advanced age (over 50) 1.38 (0.60–3.16) 0.44
Multipara ( 2) 1.89 (0.83–3.65) 0.14
Histological subtype
Serous 0.67 (0.34–1.32) 0.24
Cleacell 2.01 (0.91–4.43) 0.083
Endometrioid 0.68 (0.21–2.24) 0.53
Mucinous 1.81 (0.43–7.65) 0.42
Advanced Stage (over FIGO Stage III)
 Peritoneal dissemination
 Lymph node metastasis
 Platinum resistant 3.93 (1.62–9.54) 0.001**
 Nonoptimal debulking surgery 4.71 (1.83–12.14) 0.001** 4.70 (1.82–12.13) 0.001**

Factors correlated with deciding FIGO stages were excluded from advanced case's table. The other absent columns are excluded from final model by step wise method (*P < 0.05, **P < 0.01).