Abstract
A male patient is described with acquired immune deficiency syndrome (AIDS) who developed chronic keratoconjunctivitis and chronic sinusitis due to infection with the microsporidian Encephalitozoon cuniculi. Diagnosis was confirmed by electron microscopic examination of conjunctival epithelial cells and nasal polypectomy specimens. Treatment with propamidine isethionate 0.1% (Brolene) eye drops six times daily led to a prompt resolution of the keratoconjunctivitis.
Full text
PDF
Images in this article
Selected References
These references are in PubMed. This may not be the complete list of references from this article.
- Ashton N., Wirasinha P. A. Encephalitozoonosis (nosematosis) of the cornea. Br J Ophthalmol. 1973 Sep;57(9):669–674. doi: 10.1136/bjo.57.9.669. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Friedberg D. N., Stenson S. M., Orenstein J. M., Tierno P. M., Charles N. C. Microsporidial keratoconjunctivitis in acquired immunodeficiency syndrome. Arch Ophthalmol. 1990 Apr;108(4):504–508. doi: 10.1001/archopht.1990.01070060052047. [DOI] [PubMed] [Google Scholar]
- Lowder C. Y., Meisler D. M., McMahon J. T., Longworth D. L., Rutherford I. Microsporidia infection of the cornea in a man seropositive for human immunodeficiency virus. Am J Ophthalmol. 1990 Feb 15;109(2):242–244. doi: 10.1016/s0002-9394(14)76005-2. [DOI] [PubMed] [Google Scholar]
- MATSUBAYASHI H., KOIKE T., MIKATA I., TAKEI H., HAGIWARA S. A case of Encephalitozoon-like body infection in man. AMA Arch Pathol. 1959 Feb;67(2):181–187. [PubMed] [Google Scholar]
- Margileth A. M., Strano A. J., Chandra R., Neafie R., Blum M., McCully R. M. Disseminated nosematosis in an immunologically compromised infant. Arch Pathol. 1973 Mar;95(3):145–150. [PubMed] [Google Scholar]
- Pinnolis M., Egbert P. R., Font R. L., Winter F. C. Nosematosis of the cornea. Case report, including electron microscopic studies. Arch Ophthalmol. 1981 Jun;99(6):1044–1047. doi: 10.1001/archopht.1981.03930011044012. [DOI] [PubMed] [Google Scholar]
- Wright P., Warhurst D., Jones B. R. Acanthamoeba keratitis successfully treated medically. Br J Ophthalmol. 1985 Oct;69(10):778–782. doi: 10.1136/bjo.69.10.778. [DOI] [PMC free article] [PubMed] [Google Scholar]