Skip to main content
PMC home page
The British Journal of Ophthalmology logoLink to The British Journal of Ophthalmology
. 1992 May;76(5):313–315. doi: 10.1136/bjo.76.5.313

Malignant melanoma of the optic nerve head in a case of oculodermal melanocytosis.

M Unal 1, I Gunalp 1, A Deery 1, I Durak 1, S Erekul 1, O Bulay 1
PMCID: PMC504266  PMID: 1390518

Abstract

Malignant melanoma of the uveal tract, orbit, and brain have been reported to occur in patients with oculodermal melanocytosis. A 60-year-old Caucasian man with oculodermal melanocytosis developed a malignant melanoma of the optic nerve head in the left eye. This case is the first reported example of a malignant melanoma developing in the optic nerve associated with oculodermal melanocytosis. After presentation the patient refused surgery for 19 months and the progression of the tumour necessitated an exenteration of the orbit.

Full text

PDF

Images in this article

313Image
on p.313
314Image
on p.314
314Image
on p.314
315Image
on p.315
315Image
on p.315
315Image
on p.315

Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. DORSEY C. S., MONTGOMERY H. Blue nevus and its distinction from Mongolian spot and the nevus of Ota. J Invest Dermatol. 1954 Mar;22(3):225–236. doi: 10.1038/jid.1954.28. [DOI] [PubMed] [Google Scholar]
  2. Dutton J. J., Anderson R. L., Schelper R. L., Purcell J. J., Tse D. T. Orbital malignant melanoma and oculodermal melanocytosis: report of two cases and review of the literature. Ophthalmology. 1984 May;91(5):497–507. doi: 10.1016/s0161-6420(84)34261-0. [DOI] [PubMed] [Google Scholar]
  3. Font R. L., Reynolds A. M., Jr, Zimmerman L. E. Diffuse malignant melanoma of the iris in the nevus of Ota. Arch Ophthalmol. 1967 Apr;77(4):513–518. doi: 10.1001/archopht.1967.00980020515014. [DOI] [PubMed] [Google Scholar]
  4. Gonder J. R., Shields J. A., Albert D. M., Augsburger J. J., Lavin P. T. Uveal malignant melanoma associated with ocular and oculodermal melanocytosis. Ophthalmology. 1982 Aug;89(8):953–960. doi: 10.1016/s0161-6420(82)34694-1. [DOI] [PubMed] [Google Scholar]
  5. Gonder J. R., Shields J. A., Shakin J. L., Albert D. M. Bilateral ocular melanocytosis with malignant melanoma of the choroid. Br J Ophthalmol. 1981 Dec;65(12):843–845. doi: 10.1136/bjo.65.12.843. [DOI] [PMC free article] [PubMed] [Google Scholar]
  6. Halasa A. Malignant melanoma in a case of bilateral nevus of Ota. Arch Ophthalmol. 1970 Aug;84(2):176–178. doi: 10.1001/archopht.1970.00990040178010. [DOI] [PubMed] [Google Scholar]
  7. Jay B. Malignant melanoma of the orbit in a case of oculodermal melanosis. (Naevus of Ota). Br J Ophthalmol. 1965 Jul;49(7):359–363. doi: 10.1136/bjo.49.7.359. [DOI] [PMC free article] [PubMed] [Google Scholar]
  8. Nik N. A., Glew W. B., Zimmerman L. E. Malignant melanoma of the choroid in the nevus of Ota of a black patient. Arch Ophthalmol. 1982 Oct;100(10):1641–1643. doi: 10.1001/archopht.1982.01030040619013. [DOI] [PubMed] [Google Scholar]
  9. Rice C. D., Brown H. H. Primary orbital melanoma associated with orbital melanocytosis. Arch Ophthalmol. 1990 Aug;108(8):1130–1134. doi: 10.1001/archopht.1990.01070100086040. [DOI] [PubMed] [Google Scholar]
  10. Sang D. N., Albert D. M., Sober A. J., McMeekin T. O. Nevus of Ota with contralateral cerebral melanoma. Arch Ophthalmol. 1977 Oct;95(10):1820–1824. doi: 10.1001/archopht.1977.04450100122017. [DOI] [PubMed] [Google Scholar]
  11. Teekhasaenee C., Ritch R., Rutnin U., Leelawongs N. Ocular findings in oculodermal melanocytosis. Arch Ophthalmol. 1990 Aug;108(8):1114–1120. doi: 10.1001/archopht.1990.01070100070037. [DOI] [PubMed] [Google Scholar]

Articles from The British Journal of Ophthalmology are provided here courtesy of BMJ Publishing Group

RESOURCES