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. 2016 Apr 29;7(20):28765–28782. doi: 10.18632/oncotarget.9117

Figure 2. A small molecule screen identifies XAV939 as a novel inhibitor of TEAD transcriptional activity.

Figure 2

A. TEAD reporter activity of 293 cells treated for 24 hours with inhibitors at a concentration of 10μM. B. TEAD reporter activity of Hippo pathway wild-type and mutant cells treated with XAV939 or 0.1% DMSO as control (CTR) for 24 hours. C. Representative images of colony formation by the indicated cell lines treated with XAV939 or CTR. Error bars indicate SD of experiments performed in triplicate. ***P≤0.001. Student t-Test.