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. Author manuscript; available in PMC: 2016 Nov 9.
Published in final edited form as: Psychol Addict Behav. 2016 Mar 31;30(5):578–587. doi: 10.1037/adb0000173

Developmental trends in alcohol use initiation and escalation from early- to middle-adolescence: Prediction by urgency and trait affect

Hector I Lopez-Vergara 1,, Nichea S Spillane 1, Jennifer E Merrill 1, Kristina M Jackson 1
PMCID: PMC5045737  NIHMSID: NIHMS762377  PMID: 27031086

Abstract

Studies on adolescent drinking have not always been able to distinguish between initiation and escalation of drinking, because many studies include samples in which initiation has already occurred; hence initiation and escalation are often confounded. The present study draws from a dual-process theoretical framework to investigate: if changes in the likelihood of drinking initiation and escalation are predicted by a tendency towards rash action when experiencing positive and negative emotions (positive and negative urgency); and whether trait positive and negative affect moderate such effects. Alcohol naïve adolescents (n=944; age: M=12.16, SD=.96; 52% female) completed 6 semi-annual assessments of trait urgency and affect (wave-1) and alcohol use (waves 2–6). A two-part random-effects model was used to estimate changes in the likelihood of any alcohol use vs. escalation in the volume of use amongst initiators. Main effects suggest a significant association between positive affect and change in level of alcohol use amongst initiators, such that lower positive affect predicted increased alcohol involvement. This main effect was qualified by a significant interaction between positive urgency and positive affect predicting changes in the escalation of drinking, such that the effect of positive urgency was augmented for those high on trait positive affect, though only at extremely high levels of positive affect. Results suggest risk factors in the development of drinking depend on whether initiation or escalation is investigated. A more nuanced understanding of the early developmental phases of alcohol involvement can inform prevention and intervention efforts.

Keywords: alcohol, adolescence, urgency, affect, personality

Introduction

There is consensus that alcohol use is best conceptualized from a developmental framework, though there is a dearth of studies testing levels of escalation in early drinking milestones (Jackson & Sartor, 2014). Since the majority of adult drinkers first experiment with alcohol in adolescence, a full understanding of the etiology of addiction necessitates investigations of the early developmental phases of alcohol involvement; including initiation of alcohol use and early escalation in volume of drinking (Chassin, Colder, Hussong, & Sher, 2016).

Although there is a plethora of evidence suggesting that dysregulatory traits are robust individual-level correlates of alcohol involvement (Clark, Thatcher, & Tapert, 2008; Dick et al., 2010; Rogosch, Chassin, & Sher, 1990; Tarter, 1988), there is increasing consensus that psychological dysregulation is the result of distinct and interactive mechanisms (de Wit, 2008; Harnett, Lynch, Gullo, Dawe, & Loxton, 2013; Littlefield, Stevens, & Sher, 2014; Zucker, Heitzeg, & Nigg, 2011). The heterogeneous nature of liability for dysregulated action suggests that there is a need to “unpack” the specific mechanisms of individual-level risk for drinking (Duckworth & Steinberg, 2015; Nigg, 2015). Dual-process accounts of dysregulated action have the potential to “unpack” heterogeneity in alcohol involvement. The dual-process framework suggests that specific mechanisms of dysregulated action consist of two functionally distinct psychological processes: individual differences in capacity for regulation/control and individual differences in emotional reactivity (Beauchaine, 2015; Ernst, 2014; Luciana, 2006; Posner & Rothbart, 2000; Spear, 2011). The purpose of this study was to investigate the development of alcohol use from early- to middle-adolescence, by drawing from the personality literature to investigate the predictive role of regulation/control and emotional reactivity. More specifically, in this study we tested if individual differences in the predisposition to rash action when experiencing emotional states (trait urgency) interacts with individual differences in the predisposition to experience affective states (trait affect) to predict the initiation of drinking and/or early escalation in volume of alcohol use.

Regulation/control: Positive and negative urgency traits

In efforts to elucidate heterogeneity in the liability for alcohol involvement, the personality literature has distinguished between two dysregulatory traits: positive and negative urgency (Cyders et al., 2007). Positive urgency represents a predisposition to engage in rash-action when in a positive mood; negative urgency represents a predisposition to engage in rash-action when in a negative mood. Examining an individual’s liability for alcohol involvement as a function of their tendency to engage in rash action when experiencing positive and negative moods can help researchers investigate different pathways to drinking (Settles, Zapolski, & Smith, 2014). Both positive and negative urgency have been shown to predict adolescent drinking (for a meta-analytic review see Stautz & Cooper, 2013), which suggests that these two traits may be useful in explaining the role of capacity for regulation/control in the development of adolescent drinking.

However, the urgency constructs do not take into consideration how frequently people tend to experience positive and/or negative moods (Cyders & Coskunpinar, 2010). Hence, it is unknown whether the effects of urgency on alcohol involvement are driven by individual differences in trait affect. Determining whether this is the case would necessitate controlling for affect when examining the association between urgency and alcohol involvement. Alternatively, it may be that having high levels of trait positive/negative urgency in combination with high levels of trait positive/negative affect may place adolescents at increased risk for drinking. Determining whether this is the case would necessitate testing the interactive effects of urgency by trait affect. There is a dearth of research examining the concurrent and synergistic influence of urgency and affect traits, especially as applied to the early stages of alcohol involvement.

Emotional reactivity: Positive and negative affect traits

Individual differences in emotional reactivity (operationally defined as differences in the liability to experience frequent and intense emotional experiences) have been frequently assessed using trait affect (Bridgett, Oddi, Laake, Murdock, & Bachmann, 2013; Cheetham, Allen, Yucel, & Lubman, 2010; Martel, Nigg, & von Eye, 2009). Trait positive affect represents individual differences in the predisposition to experience positive moods; while trait negative affect represents individual differences in the predisposition to experience negative moods (Watson, Clark, & Tellegen, 1988). Different researchers have postulated different directions of effect for trait positive affect; high trait positive affect has been hypothesized to increase risk for drinking (Cheetham et al., 2010; Simons, Gaher, Correia, Hansen, & Christopher, 2005); as has low trait positive affect (Bowirrat & Oscar-Berman, 2005; Cheetham et al., 2010).

Research on the relationship between trait positive affect and alcohol involvement is equivocal. Positive associations have been reported between trait positive affect and college student drinking (Hussong, Hicks, Levy, & Curran, 2001); as have negative associations in both adolescent and college student samples (Colder & Chassin, 1997; Simons, Wills, & Neal, 2014; Wills, Sandy, Shinar, & Yaeger, 1999). There have also been studies reporting no relationship between trait positive affect and adolescent drinking (Elkins, King, McGue, & Iacono, 2006). In sum, the empirical evidence for the relationship between trait positive affect and drinking is contradictory. Contradictory findings may indicate that prior studies have not considered potential synergistic associations; this study will test the synergistic relationship between positive urgency and trait positive affect.

With respect to negative affect, research with both adolescent and college student samples suggests that trait negative affect is positively associated with alcohol involvement (Colder & Chassin, 1997; Chassin, Pillow, Curran, Molina, & Barrera, 1993; Creswell et al., 2015; Measelle, Stice, & Springer, 2006; Simons, et al., 2014; Wills et al., 1999; Wray, Simons, Dvorak, & Gaher, 2012); though there is also evidence to suggest no association between trait negative affect and college student drinking (Colder, 2001). Although the preponderance of evidence suggests that negative affect is positively associated with alcohol involvement, it is not fully understood whether trait negative affect precedes or is a consequence of alcohol use because most studies investigate this relationship after the initiation and some degree of escalation in drinking has occurred (Cheetham et al., 2010). The present study will capitalize on longitudinal methodology in a sample of alcohol naïve early-adolescents to establish temporal precedence in the prediction of the early stages of alcohol involvement.

Potential synergistic effects of urgency and affect

In addition to the independent effects of urgency and trait affect, these processes may interact such that positive affect may augment the effect of positive urgency – that is, positive urgency may have a stronger impact on drinking among those who frequently experience intense positive mood states. Similarly, high trait negative affect may augment the effect of negative urgency – that is, negative urgency may have a stronger impact on drinking amongst those who frequently experience intense negative mood states.

There is some evidence to suggest that urgency may interact with trait affect to predict behavior. For example, using a sample of 16 to 25 year-olds Racine et al. (2013) found that negative urgency, combined with high levels of trait negative affect, predicted dysregulated eating (binge eating and emotional eating). In a college student sample, Bresin, Carter, and Gordon (2013) found that trait negative affect and negative urgency interact to predict non-suicidal self-injury. Finally, in a college student sample positive urgency has been shown to predict greater levels of negative outcomes on a risk taking task and greater beer consumption following an experimental manipulation to increase positive affect (Cyders et al., 2010). These studies suggest that a joint investigation of urgency and trait affect may help elucidate synergistic mechanisms in the development of alcohol involvement. However, this has yet to be examined with respect to the development of adolescent drinking, and with younger adolescents.

Temporal precedence in the prediction of early-adolescent drinking

The present study seeks to investigate the main and moderated effects of urgency and affect traits on the development of adolescent drinking. When studying the early stages of adolescent drinking, it is imperative to differentiate between changes in the likelihood of drinking and escalation in volume of use amongst initiators (Brown, Catalano, Fleming, Haggerty, & Abbott, 2005; Capaldi, Stoolmiller, Kim, & Yoerger, 2009; Donovan, 2004). Neglecting to account for volume of use amongst initiators can obscure our understanding of the early stages of alcohol use, as different mechanisms may influence the initiation of alcohol use vs. escalation in volume of use (Hoffmann & Bahr, 2010). The current study establishes temporal precedence in the investigation of change in the likelihood of alcohol use initiation and change in volume of use amongst initiators. By using a sample that was recruited when participants were on the cusp of initiation, but had not yet initiated drinking, the current study is positioned to elucidate the early developmental phases of alcohol involvement. However, due to the dearth of research on these constructs disentangling alcohol use initiation vs. escalation in volume of use, we test the same hypotheses for alcohol use initiation and escalation.

Hypothesized main effects

It is expected that high levels of positive and negative urgency will predict more alcohol involvement. It is expected that high levels of trait negative affect will predict more alcohol involvement. Due to the mixed findings reported for trait positive affect, hypotheses are exploratory; with higher or lower levels of trait positive affect potentially predicting more alcohol involvement

Hypothesized moderated effects

It is expected that trait negative affect will moderate the association between negative urgency and alcohol involvement, such that the effect of negative urgency will be augmented among individuals who frequently experience intense negative emotional states. It is expected that trait positive affect will moderate the association between positive urgency and alcohol involvement, such that the effect of positive urgency will be augmented among individuals who frequently experience intense positive emotional states.

Methods

Participants

The current study draws from a larger study of 1,023 adolescents in an ongoing longitudinal project investigating the development of drinking milestones (Jackson et al., 2014). Adolescents were recruited in five cohorts from six public middle schools in Rhode Island. In order to establish temporal precedence in the initiation of drinking, the present study uses data from adolescents who reported never having had a full drink of alcohol at wave-1. Seven percent of the sample had initiated drinking by wave-1, and were removed from the analysis. The present study was based on n=944 adolescents who had never had a full drink of alcohol at wave-1, with an average age of 12.16 (SD= .96), and was evenly split in gender (52% female). Twelve percent of the sample identified as Hispanic; 77% as White, 7% as multi-racial, 5% as African-American, 3% as Asian, 2% as Native American, 6% as “other.”

Procedures

Information about the study was provided via the school setting (for a detailed description please see Jackson, Colby, Barnett, & Abar, 2015). Adolescents who expressed interest in the study and who had written informed parental consent were invited to attend a two-hour in-person group orientation session. During each session, project staff described the study and adolescents completed a computer-based 45-minute baseline survey. Follow-up assessments were conducted using a web-based survey that took approximately 45 minutes to complete. For follow-up assessments, participants were informed that the survey was open, and they used a unique user identification number and password to access the survey. Multiple reminders were given during the two-week survey window. After the baseline assessment (wave-1), the sample was followed for 5 waves including semi-annual data collection for two years (waves 2–5) and another survey one year later (wave 6). Local IRB approval was obtained for this study; and participants were compensated $25 at baseline, and $20 for each follow-up. Response rates were: 92% for wave-2, 88% for wave-3, 85% for wave-4, 83% for wave-5, and 83% for wave-6. Participants lost to attrition were more likely to be male; have less positive affect at waves 3 and 6; and have more negative affect at waves 3, 4, and 6.

Measures

Of relevance to this investigation are self-report measures of trait positive/negative urgency and affect (wave-1), and subsequent self-reported alcohol use (waves 2–6). Positive urgency was assessed by 6-items assessing the tendency to act rashly when in a positive mood (e.g., “I am surprised by the things I do while in a great mood”); negative urgency was assessed by 6-items assessing the tendency to act rashly when in a negative mood (e.g., “When I am upset I often act without thinking”) (UPPS-P; Cyders et al., 2007; Whiteside & Lynam, 2001). Response options ranged from “agree strongly” (1) to “disagree strongly” (4). The scale was scored such that higher scores indicate higher levels of urgency. Cronbach’s alpha was .85 for positive urgency; .84 for negative urgency.

Positive affect was assessed by 5-items assessing the frequency of experiencing positive emotional states (e.g., “cheerful, proud, joyful, delighted, & lively”); negative affect was assessed by 5-items assessing the frequency of experiencing negative emotional states in the past two weeks (e.g., “sad, upset, scared, miserable, & lonely”) (The Positive and Negative Affect Scale for Children; Laurent et al., 1999). Response options ranged from “Very slightly or not at all” (1) to “Extremely” (5). Cronbach’s alpha was .89 for positive affect and .81 for negative affect.

Alcohol involvement was assessed using a Quantity-Frequency measure (Sobell & Sobell, 2004), assessing frequency (average number of drinking days) and quantity (average drinks per drinking day) over two time period; the past 6 months for waves 2–5 and the past 12 months for wave-6. Quantity by frequency of drinking was calculated by multiplying the raw quantity and raw frequency variables with each other. After constructing the multiplicative quantity by frequency variables, we changed values in each variable greater than 3 standard deviations from the within-time mean to equal 3 standard deviations in order to reduce the influence of extreme cases (Tabachnick & Fidell, 1996). Extreme cases were judged relative to the mean and standard deviation of the time point they were assessed from (e.g., wave-2 QxF was recoded relative to the 3 standard deviation value of wave-2 QxF; wave-3 QxF was recoded relative to the 3 standard deviation value of wave-3 QxF). The following number of cases were recoded to equal 3 standard deviations: 9 at wave-2, 5 at wave-3, 11 at wave-4, 5 at wave-5, and 25 at wave-6.

Approach to Analysis

When investigating drug use in early-adolescence, outcomes are expected to be non-normally distributed because of a high concentration of values indicative of no use (Hoffmann & Bahr, 2010). This is to be expected given variability in initiation and given that youth have not yet established regular patterns of use. The nature of the distribution is not simply a nuisance that violates assumptions of conventional growth models (e.g., growth models that assume the presence of normally distributed data), but rather is an important feature of the phenomenon. Hence, a two-part random-effects model was used (Olsen & Schafer, 2001). These models are capable of handling non-normally distributed data by statistically disaggregating alcohol involvement into use vs. no-use in part-1 of the model; and level of use amongst drinkers in part-2 of the model, as well as by using maximum likelihood estimation that is robust to non-normality (MLR; Hox, Maas, & Brinkhuis, 2010) (for a review see Flora, 2011). We followed recommendations by Olsen & Schafer (2001), and began by testing the functional form for each part of the model separately (testing both linear and quadratic effects). A nested model approach was used to evaluate model fit (Bollen & Curran, 2006). An unconditional growth curve model with fixed effects (no variability around means) was used as the baseline comparison model. The Satorra-Bentler log likelihood chi-square test (Satorra & Bentler, 2001) was used to investigate if the addition of random intercepts and slopes improved model fit. Additionally, for Part 2 of the model we also assessed model fit by using root-mean-square error of approximation (RMSEA; Browne & Cudeck, 1993). Fit indices are not available to evaluate Part 1 of the model, hence we relied on nested model tests alone (Brown et al., 2005). Analyses were conducted in Mplus version 7.11; full information maxim likelihood estimation was used to model missing data (as opposed to using listwise deletion) (Muthen & Muthen, 2013). To compare our findings to previous studies that have tested the effects of urgency and affect traits independently, we ran both bivariate and multivariate models. Because they were significantly associated with drinking, age and gender were included as covariates. Significant interactions were probed by testing simple slopes at high and low levels of positive affect (Aiken & West, 1991).

Results

Correlations and descriptive statistics are presented in Table 1. The following prevalence rates of drinking were observed: At wave-2 13 youth (2%) reported drinking; at wave-3 22 youth (3%) reported drinking; at wave-4 30 youth (4%) reported drinking; at wave-5 45 youth (6%) reported drinking; and at wave-6 130 youth (16%) reported drinking. Frequency of drinking and quantity per drinking occasion are reported in Table 2. Nested model tests were used to evaluate model fit separately for each part of the model (see Table 3). The best fitting models consisted of a random intercept and slope for any use, and a fixed intercept and random slope for volume of use. The two-part model suggested that: change in any use was linear (mean= .88, p<.001; variance = .50, p= .01); and change in volume of use was linear (mean = .17, p=.001; variance = .01, p= .057). Change for any use did not correlate with change in volume of use (r = −.03, p= .92).

Table 1.

Correlations and descriptive statistics

Variable 1 2 3 4 5 6 7 8 9
1. Positive Urgency -- .70** −.08* .27** .02 .05 .06 .04 .15**
2. Negative Urgency -- −.11** .37** .08* −.02 .03 −.02 .15**
3. Positive Affect -- −.28** −.12** .03 −.02 .03 −.05
4. Negative Affect -- .07* −.00 .04 −.03 .10**
5. W2 QxF -- .10** .28** −.00 .24**
6. W3 QxF -- .81** .88** .15**
7. W4 QxF -- .69** .22**
8. W5 QxF -- .21**
9. W6 QxF --

 Mean (SD) 1.66 (.67) 1.98 (.76) 2.69 (.97) .88 (.78) .09 (.99) .29 (3.68) .30 (2.37) .47 (3.96) 1.82 (5.50)
 Skew .97 .38 −.75 1.13 18.49 23.65 13.65 20.41 4.06
 Kurtosis .34 −.83 .03 1.00 409.4 622.0 233.5 492.3 19.03

Note:

**

= p≤.01;

*

= p≤.05;

QxF = quantity by frequency of drinking

Table 2.

Frequency and Quantity of drinking

Mean age (SD) Wave-1 12.16 (.96) Wave-2 12.62 (.95) Wave-3 13.15 (.94) Wave-4 13.63 (.94) Wave-5 14.16 (.96) Wave-6 15.14 (.95)
Frequency

No drinking 100% 98% 97% 96% 94% 84%
1–2 times 0% 1% 1% 3% 4% 7%
3–5 times 0% 0.5% 1% 0% 1% 5%
1 per month 0% 0.5% 0.5% 1% 0.5% 2%
> 1 per month 0% 0% 0.5% 0% 0.5% 2%

Quantity

No drinking 100% 98% 97% 96% 94% 84%
< 1 drink 0% 1% 1% 1% 2% 2%
1 drink 0% 1% 1% 2% 2% 4%
2 drinks 0% 0% 1% 0% 1% 4%
3 drinks 0% 0% 0% 1% 1% 3%
4 drinks 0% 0% 0% 0% 0% 2%
5 drinks 0% 0% 0% 0% 0% 1%
6 drinks 0% 0% 0% 0% 0% 0%

Note: Waves 1–5 = past 6 months, wave-6 = past year

Table 3.

Summary of nested model tests for any use (Part 1) and conditional mean of use (Part 2)

AIC BIC Scaled difference χ2 (df) P-value RMSEA
Part 1 of model

Fixed-intercept fixed-slope 1649.67 1659.33
Fixed-intercept random-slope 1510.06 1524.54 158.22 (1) .0001 ---
Random-intercept random-slope 1437.63 1461.76 203.21 (2) .0001 ---
Fixed quadratic slope 1439.35 1468.31 0.26 (1) .61 ---

Part 2 of model

Fixed-intercept fixed-slope 462.66 484.32
Fixed-intercept random-slope 462.03 486.78 2.98 (1) .08 .05
Random-intercept random-slope 462.12 493.06 3.17 (2) .20 .03
Fixed quadratic slope* 463.86 491.71 0.20 .65 .00

Note: Scaled difference χ2 compares results from the nested model with the previous comparison model;

*

the quadratic growth model was tested relative to the fixed-intercept random-slope model

The bivariate associations between predictors and outcomes are presented in Table 4. Older age, being female, higher scores on trait positive urgency, negative urgency, and negative affect were associated with steeper changes in likelihood of use. In addition, older age and being male was associated with faster escalation in volume of use amongst drinkers.

Table 4.

Bivariate associations

Change in likelihood of use Change in level of use amongst drinkers

Variable β(Standardized) β SE Sig. β(Standardized) β SE Sig.
Age .34 (.36) .07 <.01 .04 (.40) .02 .02
Gender −.27 (−.19) .10 <.01 .08 (.40) .03 <.01
PU .29 (.27) .07 <.01 .04 (.29) .02 .06
PA −.00 (−.00) .04 .95 −.02 (−.26) .01 .07
NU .27 (.28) .06 <.01 .01 (.10) .02 .50
NA .13 (.15) .05 .01 .01 (.07) .02 .56

Note: PU= Positive urgency; PA= Positive affect, NU= Negative urgency, NA= Negative affect; Gender coded 1= male 0= female

Multivariate associations between predictors and outcomes are presented in Table 5; pictorial depiction of multivariate effects is presented in Figure 1. Older age and female gender predicted steeper changes in likelihood of use. Male gender and lower levels of trait positive affect predicted increased alcohol involvement amongst initiators. There was a significant interaction effect of positive urgency by positive affect predicting change in volume of use amongst drinkers. When the interaction was probed at 1SD above and below the mean of positive affect, simple slopes were not significant. To examine effect of positive urgency at intense levels of positive affect, the interaction was probed at 2SD above and below the mean of positive affect. Simple slope tests suggest that positive urgency positively predicted change in volume of use at high levels of positive affect (β= .05, SE= .03, p= .05), but not at low levels of positive affect (β= −.13, SE= .08, p= .11).

Table 5.

Multivariate associations

Change in likelihood of use Change in level of use amongst drinkers

Predictor β(Standardized) βSE Sig. β(Standardized) βSE Sig.
 Age .33 (.32) .07 <.01 .03 (.32) .02 .10
 Gender −.33 (−.18) .10 <.01 .06 (.34) .03 .05
 PU .11 (.12) .06 .08 .03 (.34) .02 .10
 PA .04 (.04) .05 .43 −.03 (−.33) .01 .03
 NU .11 (.12) .07 .11 −.02 (−.27) .02 .22
 NA .06 (.07) .05 .20 −.00 (−.02) .01 .90
 PU x PA −.04 (−.04) .05 .44 .02 (.24) .01 .03
 NU x NA −.04 (−.05) .04 .28 .01 (.15) .01 .27

Note: PU= Positive urgency; PA= Positive affect, NU= Negative urgency, NA= Negative affect; Gender coded 1= male 0= female

Figure 1.

Figure 1

Visual depiction of multivariate effects

Note: QxF= Quantity x frequency of drinking; PU x PA= positive urgency by positive affect interaction; NU x NA= negative urgency by negative affect interaction; gender coded 0=female 1=male; **= p≤.01; *= p≤.05

Discussion

The current study tested the individual and synergistic effects of positive and negative urgency and positive and negative trait affect on the early developmental phases of alcohol use; specifically changes in probability of initiation and early escalation in volume of drinking from early- to middle-adolescence. This study extends previous work by disentangling initiation from early escalation in volume of drinking during the early phases of alcohol involvement. Our results suggest that changes in who experiments with alcohol does not systematically overlap with changes in how much experimenters drink. This potentially indicates that drinking is sporadic in this population, and that initiation and escalation may be distinct drinking milestones. We also extend previous work by prospectively examining positive and negative urgency’s relationship with alcohol initiation, as previous work has focused on alcohol consumption and problems (Stautz & Cooper, 2013), or the initiation of drinking in cross-sectional samples (Gunn & Smith, 2010).

Due to the heterogeneous nature of liability towards dysregulated action, it has been suggested that the unique effects of personality variables should be tested when investigating substance use (Gullo, Loxton, & Dawe, 2014). Hence we ran two sets of models; running separate models for each predictor vs. controlling for other predictors. Running separate models for each predictor suggested that increases in the likelihood of initiation correlated with higher levels of positive urgency, higher levels of negative urgency, higher levels of negative affect, older age, and female gender. These results suggest that positive urgency may be a risk factor for the initiation of drinking, potentially indicating a positive reinforcement pathway (Settles et al., 2014). The effects of negative urgency and negative affect as risk factors for the initiation of drinking may be indicative of a negative reinforcement pathway. These models also suggested that faster escalation in volume of use correlated with older age, and male gender.

However, the more conservative analyses testing the effect of each predictor above and beyond the effects of all other variables in the model suggested that the initiation part of the model was predicted by older age and female gender; there were no significant effects of positive urgency, negative urgency, positive affect, or negative affect. These analyses also suggested a faster escalation in volume of use amongst initiators was predicted by lower levels of positive affect, potentially indicating that youth may escalate their drinking to increase low levels of positive affect. However, main effects were qualified by a significant interaction between positive urgency and positive affect predicting faster escalation in volume of use amongst initiators. The interaction suggested that positive urgency predicts more alcohol involvement at high levels of positive affect, though only at extremely high levels of positive affect (this synergistic effect may only apply to the 2.5% of the population who score above 2 standard deviations of trait positive affect). These results are consistent with the theoretical view of positive urgency as being particularly relevant for rash action when experiencing extreme levels of positive affect (Cyders et al., 2007). Risk towards the early escalation in volume of drinking may require a relatively extreme personality style, and this personality style may be characterized by a liability to engage in rash positive mood dependent action.

It is important to note that running separate models for each predictor vs. controlling for other variables in the model yielded substantially different findings. Although there is a dearth of research disentangling early developmental changes in alcohol involvement, running separate models for each predictor aligns more closely to previous findings in the literature (e.g., Adams, Kaiser, Lynam, Charnigo, & Milich, 2012; Gunn & Smith, 2010; Karyadi & King, 2011; Phillips, Hine, & Marks, 2009), suggesting that positive urgency, negative urgency, and trait negative affect are associated with alcohol involvement. These effects of urgency are consistent with personality models of dysregulated action (Cyders & Smith, 2008), and the effect of trait negative affect is consistent with models suggesting that drinking may be motivated by negative reinforcement processes (Greeley & Oei, 1999). However, these models preclude inferences regarding the incremental value of these constructs; and to assess incremental value we concurrently modeled all personality predictors in the same model.

The more stringent test of controlling for other predictors has been suggested to be a better fit with the heterogeneous nature of dysregulated action (Gullo et al., 2014), as this approach captures the unique overlap of these mechanisms with alcohol involvement. This approach suggested that lower levels of positive affect predicted faster escalation in level of drinking amongst initiators. Although positive urgency did not predict escalation in level of drinking at mean levels of positive affect, it did at extremely high levels of positive affect. This supports “dual-process” models of dysregulated action, which suggest that risk for alcohol involvement is the result of the synergistic influence of both regulatory and reactive processes (e.g., Steinberg & Chein, 2015; Jonker, Ostafin, Glashouwer, van Hemel-Ruiter, & de Jong, 2014).

The lack of effects of negative urgency and affect when controlling for other predictors calls into question a causal direction from negative emotionality to drinking, at least from early- to middle-adolescence. Positive reinforcement may be more important for the early stages of alcohol use, with a negative reinforcement pathway not becoming evident until later stages of use (Hussong, Jones, Stein, Baucom, & Boeding, 2011; Scalco et al., 2014). Future work that follows adolescents as they transition into late-adolescence and emerging adulthood is needed to investigate if negative reinforcement becomes more prominent later in development.

Opting to control vs. not control for other personality predictors has substantial implications for our theoretical understanding of personality as a predictor of substance use (Gullo et al., 2014). On the one hand, as there is a plethora of different personality models used to predict alcohol use, not controlling for other personality variables may result in an overestimation of the extent to which different personality constructs are involved in the etiology of drinking (i.e., type I error). Gullo et al. (2014) support this position and argue that the literature is saturated by a plethora of potentially redundant personality variables predicting substance use, and argue that reducing the number of variables involved in substance use can move the literature towards a more parsimonious understanding of personality risk factors. On the other hand, including too many covariates in any model may obscure findings due to excessive multicollinearity. This issue is not likely to be solved via statistical means, and future theoretically-based work is needed to provide guidance as to the most optimal approach to investigate the personality-substance use link.

Though an examination of gender was not a primary aim of this study, some interesting findings emerged. The effect of gender depended on the facet of drinking under investigation; being female correlated with steeper changes in the likelihood of initiation, whereas being male correlated with faster escalation in volume of use amongst initiators. These results suggest that gender differences in the development of drinking may depend on the facet of alcohol use that is being investigated (Jackson, 2010). Females progress faster in the initiation of alcohol use, potentially because females transition through puberty earlier than males (Spear, 2010) which may facilitate opportunities to experiment with alcohol from early- to middle-adolescence. However, once initiation occurs, males escalate their level of use faster (Chen & Jacobson, 2012). Previous research suggest that females experience more severe acute negative effects from drinking (e.g., cognitive and motor effects of drinking at low doses) (Nolen-Hoeksema, 2004), which may protect against the escalation of use. Alternatively, there is evidence that social sanctions against drunkenness are greater for women than men, and hence socially constructed gender roles may account for these findings (Nolen-Hoeksema, 2004). Future research exploring the mechanisms of gender differences is needed in efforts to inform the development of gender sensitive, etiologically informed interventions.

Strengths, limitations, and future directions

The large sample of youth with limited experience with alcohol is a strength of this study, as it allows us to establish temporal precedence and assert the directionality of effects with greater confidence. Additionally, the prospective nature of the study is a strength as it allows for the investigation of changes in alcohol use from early- to middle-adolescence, as is the analytic framework that facilitates the investigation of changes in probability of drinking vs. escalation in volume of drinking. Within the context of these strengths are some limitations, some of which are shared with the broader literature on adolescent drinking. Our measurement of key constructs relied exclusively on self-report, which may be prone to memory/recall biases or social desirability. Future studies that rely on more objective approaches to measuring personality (e.g., performance-based tasks) are needed. Another limitation involves the low representation of racial/ethnic minorities in the sample. Previous research suggests that liability to dysregulated action may be influenced by chronic environmental adversity (Bickel, Moody, Quisenberry, Ramey, & Sheffer, 2014; Shonkoff, 2012); as minorities are exposed to higher levels of systemic adversity, future studies may benefit from selecting higher representation of minority groups to determine if similar pathways are important in alcohol use initiation and escalation. Additionally, the lack of consideration of the environment prevents an understanding of the dynamic interplay of contextual and individual-level factors. Future studies may benefit from examining if the effects of individual level risk factors are more important in different contexts (e.g., across neighborhoods that differ by socioeconomic status). Finally, our results may not generalize to youth who initiate drinking prior to the middle school years.

In sum, the present study provides evidence that the correlates of the early developmental stages of drinking likely depend on the specific facet of alcohol use under consideration. Additionally, when controlling for different sources of liability for dysregulated action, low positive affect emerged as a predictor of drinking, suggesting that mood enhancement may be a mechanism of action in the early stages of drinking. These findings suggest that targeted prevention efforts may benefit from shaping youth to develop non-drug using sources of positive reinforcement. However, targeted prevention efforts may need to differentiate between various forms of liability for alcohol use, as for a small percentage of the population the escalation in level of use may be driven by a tendency to engage in rash, positive mood dependent action. It may be the case that a broad repertoire of non-drug using rewarding activities can delay the early escalation of drinking amongst adolescents who experiment with alcohol.

Acknowledgments

The sample was drawn from a large study funded by NIAAA R01 AA16838 (PI Jackson).

Footnotes

The authors declare that there are no conflicts of interest.

References

  1. Adams ZW, Kaiser AJ, Lynam DR, Charnigo RJ, Milich R. Drinking motives as mediators of the impulsivity-substance use relation: Pathways for negative urgency, lack of premeditation, and sensation seeking. Addictive Behaviors. 2012;37:848–855. doi: 10.1016/j.addbeh.2012.03.016. [DOI] [PMC free article] [PubMed] [Google Scholar]
  2. Aiken LS, West SG. Multiple regression: Testing and interpreting interactions. Sage; 1991. [Google Scholar]
  3. Beauchaine TP. Future directions in emotion dysregulation and youth psychopathology. Journal of Clinical Child & Adolescent Psychology. 2015;44:875–896. doi: 10.1080/15374416.2015.1038827. [DOI] [PubMed] [Google Scholar]
  4. Bickel WK, Moody L, Quisenberry AJ, Ramey CT, Sheffer CE. A competing neurobehavioral decision systems model of SES-related helath and behavioral disparities. Preventive Medicine. 2014;68:37–43. doi: 10.1016/j.ypmed.2014.06.032. [DOI] [PMC free article] [PubMed] [Google Scholar]
  5. Bollen KA, Curran PJ. Latent curve models: A structural equation perspective. John Wiley & Sons; 2006. [Google Scholar]
  6. Bowirrat A, Oscar-Berman M. Relationship between dopaminergic neurotransmission, alcoholism, and reward deficiency syndrome. American Journal of Medical Genetics Part B: Neuropsychiatric Genetics. 2005;132:29–37. doi: 10.1002/ajmg.b.30080. [DOI] [PubMed] [Google Scholar]
  7. Bresin K, Carter DL, Gordon KH. The relationship between trait impulsivity, negative affective states, and urge for nonsuicidal self-injury: A daily diary study. Psychiatry Research. 2013;205:227–231. doi: 10.1016/j.psychres.2012.09.033. [DOI] [PubMed] [Google Scholar]
  8. Bridgett DJ, Oddi KB, Laake LM, Murdock KW, Bachmann MN. Integrating and differentiating aspects of self-regulation: Effortful control, executive functioning, and links to negative affectivity. Emotion. 2013;13:47–63. doi: 10.1037/a0029536. [DOI] [PubMed] [Google Scholar]
  9. Brown EC, Catalano RF, Fleming CB, Haggerty KP, Abbott RD. Adolescent substance use outcomes in the Raising Healthy Children project: A two-part latent growth curve analysis. Journal of Consulting and Clinical Psychology. 2005;73:699–710. doi: 10.1037/0022-006X.73.4.699. [DOI] [PubMed] [Google Scholar]
  10. Capaldi DM, Stoolmiller M, Kim HK, Yoerger K. Growth in alcohol use in at-risk adolescent boys: Two-part random effects prediction models. Drug and Alcohol Dependence. 2009;105:109–117. doi: 10.1016/j.drugalcdep.2009.06.013. [DOI] [PMC free article] [PubMed] [Google Scholar]
  11. Chassin L, Colder CR, Hussong A, Sher KJ. Developmental Psychopathology, Volume 3: Risk, Disorder, and Adaptation. 3. John Wiley & Sons, Inc; 2016. Substance use and substance use disorders; pp. 833–897. [Google Scholar]
  12. Chassin L, Pillow D, Curran P, Molina B, Barrera M. Relation of parental alcoholism to early adolescent substance use: A test of three mediating mechanisms. Journal of Abnormal Psychology. 1993;102:3–9. doi: 10.1037//0021-843x.102.1.3. [DOI] [PubMed] [Google Scholar]
  13. Cheetham A, Allen NB, Yucel M, Lubman DI. The role of affective dysregulation in drug addiction. Clinical Psychology Review. 2010;30:621–634. doi: 10.1016/j.cpr.2010.04.005. [DOI] [PubMed] [Google Scholar]
  14. Chen P, Jacobson KC. Developmental trajectories of substance use from early adolescence to young adulthood: Gender and racial/ethnic differences. Journal of Adolescent Health. 2012;50:154–163. doi: 10.1016/j.jadohealth.2011.05.013. [DOI] [PMC free article] [PubMed] [Google Scholar]
  15. Clark DB, Thatcher DL, Tapert SF. Alcohol, psychological dysregulation, and adolescent brain development. Alcoholism: Clinical and Experimental Research. 2008;32:375–385. doi: 10.1111/j.1530-0277.2007.00601.x. [DOI] [PubMed] [Google Scholar]
  16. Colder CR. Life stress, physiological and subjective indexes of negative emotionality, and coping reasons for drinking: Is there evidence for a self-medication model of alcohol use? Psychology of Addictive Behaviors. 2001;15:237–245. [PubMed] [Google Scholar]
  17. Colder CR, Chassin L. Affectivity and impulsivity: Temperament risk for adolescent alcohol involvement. Psychology of Addictive Behaviors. 1997;11:83–97. [Google Scholar]
  18. Colder CR, Read JP, Wieczorek WF, Eiden RD, Lengua LJ, Hawk LW, Trucco EM, Lopez-Vergara HI. Cognitive appraisals of alcohol use in early adolescence: Psychosocial predictors and reciprocal associations with alcohol use. Journal of Early Adolescence. doi: 10.1177/0272431615611256. In press. [DOI] [PMC free article] [PubMed] [Google Scholar]
  19. Creswell KG, Chung T, Wright AG, Clark DB, Black JJ, Martin CS. Personality, negative affect coping, and drinking alone: A structural equation modeling approach to examine correlates of adolescent solitary drinking. Addiction. 2015;110:775–783. doi: 10.1111/add.12881. [DOI] [PMC free article] [PubMed] [Google Scholar]
  20. Cyders MA, Coskunpinar A. Is urgency emotionality? Separating urgent behaviors from effects of emotional experiences. Personality and Individual Differences. 2010;48:839–844. doi: 10.1016/j.paid.2010.02.009. [DOI] [PMC free article] [PubMed] [Google Scholar]
  21. Cyders MA, Smith GT. Emotion-based disposition to rash action: Positive and negative urgency. Psychological Bulletin. 2008;134:807–828. doi: 10.1037/a0013341. [DOI] [PMC free article] [PubMed] [Google Scholar]
  22. Cyders MA, Smith GT, Spillane NS, Fischer S, Annus AM, Peterson C. Integration of impulsivity and positive mood to predict risky behavior: Development and validation of a measure of positive urgency. Psychological Assessment. 2007;19:107–118. doi: 10.1037/1040-3590.19.1.107. [DOI] [PubMed] [Google Scholar]
  23. Cyders MA, Zapolski TC, Combs JL, Settles RF, Fillmore MT, Smith GT. Experimental effect of positive urgency on negative outcomes from risk taking and on increased alcohol consumption. Psychology of Addictive Behaviors. 2010;24:367–375. doi: 10.1037/a0019494. [DOI] [PMC free article] [PubMed] [Google Scholar]
  24. de Wit H. Impulsivity as a determinant and consequence of drug use: A review of underlying processes. Addiction Biology. 2008;14:22–31. doi: 10.1111/j.1369-1600.2008.00129.x. [DOI] [PMC free article] [PubMed] [Google Scholar]
  25. Dick DM, Smith G, Olausson P, Mitchell SH, Leeman RF, O’Malley SS, Sher K. REVIEW: Understanding the construct of impulsivity and its relationship to alcohol use disorders. Addiction Biology. 2010;15:217–226. doi: 10.1111/j.1369-1600.2009.00190.x. [DOI] [PMC free article] [PubMed] [Google Scholar]
  26. Donovan JE. Adolescent alcohol initiation: A review of psychosocial risk factors. Journal of Adolescent Health. 2004;35:529.e7–529.e18. doi: 10.1016/j.jadohealth.2004.02.003. [DOI] [PubMed] [Google Scholar]
  27. Duckworth AL, Steinberg L. Unpacking self-control. Child Development Perspectives. 2015;9:32–37. doi: 10.1111/cdep.12107. [DOI] [PMC free article] [PubMed] [Google Scholar]
  28. Elkins IJ, King SM, McGue M, Iacono WG. Personality traits and the development of nicotine, alcohol, and illicit drug disorders: Prospective links from adolescence to young adulthood. Journal of Abnormal Psychology. 2006;115:26–39. doi: 10.1037/0021-843X.115.1.26. [DOI] [PubMed] [Google Scholar]
  29. Ernst M. The triadic model perspective for the study of adolescent motivated behavior. Brain and Cognition. 2014;89:104–111. doi: 10.1016/j.bandc.2014.01.006. [DOI] [PMC free article] [PubMed] [Google Scholar]
  30. Flora DB. Two-part modeling of semicontinuous longitudinal variables: A comparison of approaches. Methodology: European Journal of Research Methods for the Behavioral and Social Sciences. 2011;7:145–156. [Google Scholar]
  31. Greeley J, Oei T. Alcohol and tension reduction. In: Leonard KE, Blane HT, editors. Psychological Theories of Drinking and Alcoholism. 2. New York: Guilford Press; 1999. pp. 14–53. [Google Scholar]
  32. Gullo MJ, Loxton NJ, Dawe S. Impulsivity: Four ways five factors are not basic to addiction. Addictive Behaviors. 2014:1547–1556. doi: 10.1016/j.addbeh.2014.01.002. [DOI] [PubMed] [Google Scholar]
  33. Gunn RL, Smith GT. Risk factors for elementary school drinking: Pubertal status, personality, and alcohol expectancies concurrently predict 5th grade alcohol consumption. Psychology of Addictive Behaviors. 2010;24:617–627. doi: 10.1037/a0020334. [DOI] [PMC free article] [PubMed] [Google Scholar]
  34. Handley ED, Chassin L, Haller MM, Bountress KE, Dandreaux D, Beltran I. Do executive and reactive disinhibition mediate the effects of familial substance use disorders on adolescent externalizing outcomes? Journal of Abnormal Psychology. 2011;120:528–542. doi: 10.1037/a0024162. [DOI] [PMC free article] [PubMed] [Google Scholar]
  35. Harnett PH, Lynch SJ, Gullo MJ, Dawe S, Loxton N. Personality, cognition and hazardous drinking: Support for the 2-Component Approach to Reinforcing Substances Model. Addictive Behaviors. 2013;38:2945–2948. doi: 10.1016/j.addbeh.2013.08.017. [DOI] [PubMed] [Google Scholar]
  36. Hoffmann JP, Bahr SJ. Estimating the prevalence and frequency of adolescent drug use: Do the models fit the measure? Journal of Drug Issues. 2010;40:871–899. [Google Scholar]
  37. Hox JJ, Maas CJM, Brinkhuis JS. The effect of estimation method and sample size in multilevel structural equation modeling. Statistica Neerlandica. 2010;64:157–170. [Google Scholar]
  38. Hussong AM, Hicks RE, Levy SA, Curran PJ. Specifying the relations between affect and heavy alcohol use among young adults. Journal of Abnormal Psychology. 2001;110:449–461. doi: 10.1037//0021-843x.110.3.449. [DOI] [PubMed] [Google Scholar]
  39. Hussong AM, Jones DJ, Stein GL, Baucom DH, Boeding S. An internalizing pathway to alcohol use and disorder. Psychology of Addictive Behaviors. 2011;25:390–404. doi: 10.1037/a0024519. [DOI] [PMC free article] [PubMed] [Google Scholar]
  40. Jackson KM. Progression through early drinking milestones in an adolescent treatment sample. Addiction. 2010;105:438–449. doi: 10.1111/j.1360-0443.2009.02800.x. [DOI] [PMC free article] [PubMed] [Google Scholar]
  41. Jackson KM, Colby SM, Barnett NP, Abar CC. Prevalence and correlates of sipping alcohol in a prospective middle school sample. Psychology of Addictive Behaviors. 2015;29(3):766–778. doi: 10.1037/adb0000072. [DOI] [PMC free article] [PubMed] [Google Scholar]
  42. Jackson KM, Roberts M, Colby SM, Barnett NP, Abar CC, Merrill J. Willingness to drink as a function of peer offers and peer norms in early adolescence. Journal of Studies on Alcohol and Drugs. 2014;75:404–414. doi: 10.15288/jsad.2014.75.404. [DOI] [PMC free article] [PubMed] [Google Scholar]
  43. Jackson KM, Sartor CE. The natural course of substance use and dependence. The Oxford Handbook of Substance Use Disorders. 2014;1 early on-line release. [Google Scholar]
  44. Jonker NC, Ostafin BD, Glashouwer KA, van Hemel-Ruiter ME, de Jong PJ. Reward and punishment sensitivity and alcohol use: The moderating role of executive control. Addictive Behaviors. 2014;39:945–948. doi: 10.1016/j.addbeh.2013.12.011. [DOI] [PubMed] [Google Scholar]
  45. Karyadi KA, King KM. Urgency and negative emotions: Evidence for moderation on negative alcohol consequences. Personality and Individual Differences. 2011;51:635–640. [Google Scholar]
  46. Laurent J, Catanzaro SJ, Joiner TE, Rudolph KD, Potter KI, Lambert S, Osborne L, Gathright T. A measure of positive and negative affect for children: Scale development and preliminary validation. Psychological Assessment. 1999;11:326–338. [Google Scholar]
  47. Littlefield AK, Stevens AK, Sher KJ. Impulsivity and alcohol involvement: Multiple, distinct constructs and processes. Current Addictions Report. 2014;1:33–40. doi: 10.1007/s40429-013-0004-5. [DOI] [PMC free article] [PubMed] [Google Scholar]
  48. Lopez-Vergara HI, Colder CR, Hawk LW, Wieczorek WF, Eiden LJ, Read JP. Reinforcement sensitivity theory and alcohol outcome expectancies in early adolescence. American Journal of Drug and Alcohol Abuse. 2012;38:130–134. doi: 10.3109/00952990.2011.643973. [DOI] [PMC free article] [PubMed] [Google Scholar]
  49. Luciana M. Cognitive neuroscience and the prefrontal cortex: Normative development and vulnerability to psychopathology. In: Cicchetti D, Cohen DJ, editors. Developmental Psychopathology (2nd Ed.), Vol. 2: Developmental Neuroscience. John Wiley & Sons, Inc; 2006. pp. 292–331. [Google Scholar]
  50. Martel MM, Nigg JT, von Eye A. How do trait dimensions map onto ADHD symptom domains? Journal of Abnormal Child Psychology. 2009;37:337–348. doi: 10.1007/s10802-008-9255-3. [DOI] [PMC free article] [PubMed] [Google Scholar]
  51. Measelle JR, Stice E, Springer DW. A prospective test of the negative affect model of substance abuse: Moderating effects of social support. Psychology of Addictive Behaviors. 2006;20:225–233. doi: 10.1037/0893-164X.20.3.225. [DOI] [PMC free article] [PubMed] [Google Scholar]
  52. Muthen LK, Muthen BO. Mplus: Statistical analysis with latent variables. User’s guide (Version 7.11) Los Angeles, CA: Muthen and Muthen; 2013. [Google Scholar]
  53. Nigg JT. Editorial: The shape of the nosology to come in developmental psychopathology. Journal of Child Psychology and Psychiatry. 2015;56:397–399. doi: 10.1111/jcpp.12408. [DOI] [PMC free article] [PubMed] [Google Scholar]
  54. Nolen-Hoeksema S. Gender differences in reisk factors and consequences for alcohol use and problems. Clinical Psychology Review. 2004;24:981–1010. doi: 10.1016/j.cpr.2004.08.003. [DOI] [PubMed] [Google Scholar]
  55. Olsen MK, Schafer JL. A two-part random-effects model for semicontinuous longitudinal data. Journal of the American Statistical Association. 2001;96:730–745. [Google Scholar]
  56. Phillips WJ, Hine DW, Marks ADG. Individual differences in trait urgency moderate the role of the affect heuristic in adolescent binge drinking. Personality and Individual Differences. 2009;47:829–834. [Google Scholar]
  57. Posner MI, Rothbart MK. Developing mechanisms of self-regulation. Development and Psychopathology. 2000;12:427–441. doi: 10.1017/s0954579400003096. [DOI] [PubMed] [Google Scholar]
  58. Racine SE, Keel PK, Burt SA, Sisk CL, Neale M, Boker S, Klump KL. Exploring the relationship between negative urgency and dysregulated eating: Etiologic associations and the role of negative affect. Journal of Abnormal Psychology. 2013;122:433–444. doi: 10.1037/a0031250. [DOI] [PMC free article] [PubMed] [Google Scholar]
  59. Rogosch F, Chassin L, Sher KJ. Personality variables as mediators and moderators of family history risk for alcoholism: Conceptual and methodological issues. Journal of Studies on Alcohol. 1990;51:310–318. doi: 10.15288/jsa.1990.51.310. [DOI] [PubMed] [Google Scholar]
  60. Satorra A, Bentler PM. A scaled difference chi-square test statistic for moment structure analysis. Psychometrika. 2001;66:507–514. doi: 10.1007/s11336-009-9135-y. [DOI] [PMC free article] [PubMed] [Google Scholar]
  61. Scalco MD, Colder CR, Hawk LW, Jr, Read JP, Wieczorek WF, Lengua LJ. Internalizing and externalizing problem behavior and early adolescent substance use: A test of a latent variable interaction and conditional indirect effects. Psychology of Addictive Behaviors. 2014;28:828–840. doi: 10.1037/a0035805. [DOI] [PMC free article] [PubMed] [Google Scholar]
  62. Settles RF, Cyders MA, Smith GT. Longitudinal validation of the acquired preparedness model of drinking risk. Psychology of Addictive Behaviors. 2010;24:198–208. doi: 10.1037/a0017631. [DOI] [PMC free article] [PubMed] [Google Scholar]
  63. Settles RE, Zapolski TCB, Smith GT. Longitudinal test of a developmental model of the transition to early drinking. Journal of Abnormal Psychology. 2014;123:141–151. doi: 10.1037/a0035670. [DOI] [PMC free article] [PubMed] [Google Scholar]
  64. Shonkoff JP. Leveraging the biology of adversity to address the roots of disparities in health and development. Proceedings of the National Academy of Sciences. 2012;109(Supplement 2):17302–17307. doi: 10.1073/pnas.1121259109. [DOI] [PMC free article] [PubMed] [Google Scholar]
  65. Simons JS, Gaher RM, Correia CJ, Hansen CL, Christopher MS. An affective-motivational model of marijuana and alcohol problems among college students. Psychology of Addictive Behaviors. 2005;19:326–334. doi: 10.1037/0893-164X.19.3.326. [DOI] [PubMed] [Google Scholar]
  66. Simons JS, Wills TA, Neal DJ. The many faces of affect: A multilevel model of drinking frequency/quantity and alcohol dependence symptoms among young adults. Journal of Abnormal Psychology. 2014;123:676–694. doi: 10.1037/a0036926. [DOI] [PMC free article] [PubMed] [Google Scholar]
  67. Sobell LC, Sobell MB. Alcohol Consumption Measures. 2004 Retrieved May 13 2011 from http://pubs.niaaa.nih.gov/publications/Assesing%20Alcohol/measures.htm.
  68. Spear LP. The behavioral neuroscience of adolescence. W. W., Norton & Company, Inc; New York, NY: 2010. [Google Scholar]
  69. Spear LP. Rewards, aversions and affect in adolescence: Emerging convergences across laboratory animal and human data. Developmental Cognitive Neuroscience. 2011;1:390–403. doi: 10.1016/j.dcn.2011.08.001. [DOI] [PMC free article] [PubMed] [Google Scholar]
  70. Stautz K, Cooper A. Impulsivity-related personality traits and adolescent alcohol use: A meta-analytic review. Clinical Psychology Review. 2013;33:574–592. doi: 10.1016/j.cpr.2013.03.003. [DOI] [PubMed] [Google Scholar]
  71. Steinberg L, Chein JM. Multiple accounts of adolescent impulsivity. Proceedings of the National Academy of Sciences. 2015 doi: 10.1073/pnas.1509732112. 201509732. [DOI] [PMC free article] [PubMed] [Google Scholar]
  72. Tabachnick BG, Fidell LS. Using multivariate statistics. 3. Harper Collings College Publishers; New York, NY: 1996. [Google Scholar]
  73. Tarter RE. Are there inherited behavioral traits that predispose to substance abuse? Journal of Consulting and Clinical Psychology. 1988;56:189–196. doi: 10.1037//0022-006x.56.2.189. [DOI] [PubMed] [Google Scholar]
  74. Watson D, Clark LA, Tellegen A. Development and validation of brief measures of positive and negative affect: The PANAS scales. Journal of Personality and Social Psychology. 1988;54:1063–1070. doi: 10.1037//0022-3514.54.6.1063. [DOI] [PubMed] [Google Scholar]
  75. Whiteside SP, Lynam DR. The five factor model and impulsivity: Using a structural model of personality to understand impulsivity. Personality and Individual Differences. 2001;30:669–689. [Google Scholar]
  76. Wills TA, Sandy JM, Shinar O, Yaeger A. Contributions of negative affect to adolescent substance use: Test of a bidimensional model in a longitudinal study. Psychology of Addictive Behaviors. 1999;13:327–338. [Google Scholar]
  77. Wray TB, Simons JS, Dvorak RD, Gaher RM. Trait-based affective processes in alcohol-involved “risk behaviors. Addictive Behaviors. 2012;37:1230–1239. doi: 10.1016/j.addbeh.2012.06.004. [DOI] [PMC free article] [PubMed] [Google Scholar]
  78. Zucker RA, Heitzeg MM, Nigg JT. Parsing the undercontrol-disinhibition pathway to substance use disorders: A multilevel developmental problem. Child Development Perspectives. 2011;5:248–255. doi: 10.1111/j.1750-8606.2011.00172.x. [DOI] [PMC free article] [PubMed] [Google Scholar]

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