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. 1993 Nov;77(11):709–712. doi: 10.1136/bjo.77.11.709

Contrast sensitivity function in Graves' ophthalmopathy and dysthyroid optic neuropathy.

M S Suttorp-Schulten 1, R Tijssen 1, M P Mourits 1, P Apkarian 1
PMCID: PMC504629  PMID: 8280684

Abstract

Contrast sensitivity function was measured by a computer automated method on 38 eyes with dysthyroid optic neuropathy and 34 eyes with Graves' ophthalmopathy only. The results were compared with 74 healthy control eyes. Disturbances of contrast sensitivity functions were found in both groups when compared with controls. The eyes affected with dysthyroid optic neuropathy showed pronounced loss of contrast sensitivity in the low frequency range, which facilitates differentiation between the two groups.

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Selected References

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  1. Apkarian P., Tijssen R., Spekreijse H., Regan D. Origin of notches in CSF: optical or neural? Invest Ophthalmol Vis Sci. 1987 Mar;28(3):607–612. [PubMed] [Google Scholar]
  2. Drucker M. D., Savino P. J., Sergott R. C., Bosley T. M., Schatz N. J., Kubilis P. S. Low-contrast letter charts to detect subtle optic [corrected] neuropathies. Am J Ophthalmol. 1988 Feb 15;105(2):141–145. doi: 10.1016/0002-9394(88)90176-6. [DOI] [PubMed] [Google Scholar]
  3. Feldon S. E., Muramatsu S., Weiner J. M. Clinical classification of Graves' ophthalmopathy. Identification of risk factors for optic neuropathy. Arch Ophthalmol. 1984 Oct;102(10):1469–1472. doi: 10.1001/archopht.1984.01040031189015. [DOI] [PubMed] [Google Scholar]
  4. Fells P. Orbital decompression for severe dysthyroid eye disease. Br J Ophthalmol. 1987 Feb;71(2):107–111. doi: 10.1136/bjo.71.2.107. [DOI] [PMC free article] [PubMed] [Google Scholar]
  5. Fells P. Thyroid-associated eye disease: clinical management. Lancet. 1991 Jul 6;338(8758):29–32. doi: 10.1016/0140-6736(91)90014-g. [DOI] [PubMed] [Google Scholar]
  6. Guy J. R., Fagien S., Donovan J. P., Rubin M. L. Methylprednisolone pulse therapy in severe dysthyroid optic neuropathy. Ophthalmology. 1989 Jul;96(7):1048–1053. doi: 10.1016/s0161-6420(89)32784-9. [DOI] [PubMed] [Google Scholar]
  7. Jacobson D. H., Gorman C. A. Endocrine ophthalmopathy: current ideas concerning etiology, pathogenesis, and treatment. Endocr Rev. 1984 Spring;5(2):200–220. doi: 10.1210/edrv-5-2-200. [DOI] [PubMed] [Google Scholar]
  8. Kennerdell J. S., Rosenbaum A. E., El-Hoshy M. H. Apical optic nerve compression of dysthyroid optic neuropathy on computed tomography. Arch Ophthalmol. 1981 May;99(5):807–809. doi: 10.1001/archopht.1981.03930010807002. [DOI] [PubMed] [Google Scholar]
  9. Lin S., Reiter K., Dreher A. W., Frucht-Pery J., Feldman S. T. The effect of pterygia on contrast sensitivity and glare disability. Am J Ophthalmol. 1989 Apr 15;107(4):407–410. doi: 10.1016/0002-9394(89)90665-x. [DOI] [PubMed] [Google Scholar]
  10. Marmor M. F. Contrast sensitivity versus visual acuity in retinal disease. Br J Ophthalmol. 1986 Jul;70(7):553–559. doi: 10.1136/bjo.70.7.553. [DOI] [PMC free article] [PubMed] [Google Scholar]
  11. Mourits M. P., Koornneef L., Wiersinga W. M., Prummel M. F., Berghout A., van der Gaag R. Orbital decompression for Graves' ophthalmopathy by inferomedial, by inferomedial plus lateral, and by coronal approach. Ophthalmology. 1990 May;97(5):636–641. doi: 10.1016/s0161-6420(90)32532-0. [DOI] [PubMed] [Google Scholar]
  12. Mourits M. P., Suttorp-Schulten M. S., Tijssen R. O., Apkarian P. Contrast sensitivity and the diagnosis dysthyroid optic neuropathy. Doc Ophthalmol. 1990 Apr-Jul;74(4):329–335. doi: 10.1007/BF00145817. [DOI] [PubMed] [Google Scholar]
  13. Neigel J. M., Rootman J., Belkin R. I., Nugent R. A., Drance S. M., Beattie C. W., Spinelli J. A. Dysthyroid optic neuropathy. The crowded orbital apex syndrome. Ophthalmology. 1988 Nov;95(11):1515–1521. doi: 10.1016/s0161-6420(88)32978-7. [DOI] [PubMed] [Google Scholar]
  14. Nordmann J. P., Saraux H., Roullet E. Contrast sensitivity in multiple sclerosis. A study in 35 patients with and without optic neuritis. Ophthalmologica. 1987;195(4):199–204. doi: 10.1159/000309813. [DOI] [PubMed] [Google Scholar]
  15. Prummel M. F., Mourits M. P., Berghout A., Krenning E. P., van der Gaag R., Koornneef L., Wiersinga W. M. Prednisone and cyclosporine in the treatment of severe Graves' ophthalmopathy. N Engl J Med. 1989 Nov 16;321(20):1353–1359. doi: 10.1056/NEJM198911163212002. [DOI] [PubMed] [Google Scholar]
  16. Sample P. A., Juang P. S., Weinreb R. N. Isolating the effects of primary open-angle glaucoma on the contrast sensitivity function. Am J Ophthalmol. 1991 Sep 15;112(3):308–316. doi: 10.1016/s0002-9394(14)76732-7. [DOI] [PubMed] [Google Scholar]
  17. Schaefer S. D., Merritt J. H., Close L. G. Orbital decompression for optic neuropathy secondary to thyroid eye disease. Laryngoscope. 1988 Jul;98(7):712–716. doi: 10.1288/00005537-198807000-00004. [DOI] [PubMed] [Google Scholar]
  18. Skalka H. W. Comparison of Snellen acuity, VER acuity, and Arden grating scores in macular and optic nerve diseases. Br J Ophthalmol. 1980 Jan;64(1):24–29. doi: 10.1136/bjo.64.1.24. [DOI] [PMC free article] [PubMed] [Google Scholar]
  19. Trobe J. D., Glaser J. S., Laflamme P. Dysthyroid optic neuropathy. Clinical profile and rationale for management. Arch Ophthalmol. 1978 Jul;96(7):1199–1209. doi: 10.1001/archopht.1978.03910060033007. [DOI] [PubMed] [Google Scholar]
  20. Trobe J. D. Optic nerve involvement in dysthyroidism. Ophthalmology. 1981 Jun;88(6):488–492. doi: 10.1016/s0161-6420(81)34997-5. [DOI] [PubMed] [Google Scholar]
  21. Utiger R. D. Treatment of Graves' ophthalmopathy. N Engl J Med. 1989 Nov 16;321(20):1403–1405. doi: 10.1056/NEJM198911163212009. [DOI] [PubMed] [Google Scholar]
  22. Weatherill J., Yap M. Recovery of contrast sensitivity following bilateral orbital decompression: a case report. Am J Optom Physiol Opt. 1985 Oct;62(10):715–719. doi: 10.1097/00006324-198510000-00008. [DOI] [PubMed] [Google Scholar]
  23. Werner S. C. Modification of the classification of the eye changes of Graves' disease. Am J Ophthalmol. 1977 May;83(5):725–727. doi: 10.1016/0002-9394(77)90140-4. [DOI] [PubMed] [Google Scholar]
  24. Wolkstein M., Atkin A., Bodis-Wollner I. Contrast sensitivity in retinal disease. Ophthalmology. 1980 Nov;87(11):1140–1149. doi: 10.1016/s0161-6420(80)35112-9. [DOI] [PubMed] [Google Scholar]
  25. Zimmern R. L., Campbell F. W., Wilkinson I. M. Subtle disturbances of vision after optic neuritis elicited by studying contrast sensitivity. J Neurol Neurosurg Psychiatry. 1979 May;42(5):407–412. doi: 10.1136/jnnp.42.5.407. [DOI] [PMC free article] [PubMed] [Google Scholar]

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