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. 1993 Dec;77(12):805–812. doi: 10.1136/bjo.77.12.805

Applications of monoclonal antibodies in the investigation, diagnosis, and treatment of retinoblastoma.

J F Tarlton 1, D L Easty 1
PMCID: PMC504661  PMID: 8110677

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Selected References

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  1. Abiose A., Adido J., Agarwal S. C. Childhood malignancies of the eye and orbit in northern Nigeria. Cancer. 1985 Jun 15;55(12):2889–2893. doi: 10.1002/1097-0142(19850615)55:12<2889::aid-cncr2820551232>3.0.co;2-5. [DOI] [PubMed] [Google Scholar]
  2. Abramson D. H., Ellsworth R. M. Ancillary tests for the diagnosis of retinoblastoma. Bull N Y Acad Med. 1980 Mar;56(2):221–231. [PMC free article] [PubMed] [Google Scholar]
  3. Abramson D. H. Retinoblastoma 1990: diagnosis, treatment, and implications. Pediatr Ann. 1990 Jun;19(6):387–395. doi: 10.3928/0090-4481-19900601-08. [DOI] [PubMed] [Google Scholar]
  4. Allan P. M., Garson J. A., Harper E. I., Asser U., Coakham H. B., Brownell B., Kemshead J. T. Biological characterization and clinical applications of a monoclonal antibody recognizing an antigen restricted to neuroectodermal tissues. Int J Cancer. 1983 May 15;31(5):591–598. doi: 10.1002/ijc.2910310510. [DOI] [PubMed] [Google Scholar]
  5. Bagshawe K. D. Cancer drug targeting. Clin Radiol. 1985 Nov;36(6):545–551. doi: 10.1016/s0009-9260(85)80230-0. [DOI] [PubMed] [Google Scholar]
  6. Bagshawe K. D. The First Bagshawe lecture. Towards generating cytotoxic agents at cancer sites. Br J Cancer. 1989 Sep;60(3):275–281. doi: 10.1038/bjc.1989.270. [DOI] [PMC free article] [PubMed] [Google Scholar]
  7. Bahakim H. M., el-Idrissy I. M. Epidemiological observations of consanguinity and retinoblastoma in Arabia. A retrospective study. Trop Geogr Med. 1989 Oct;41(4):361–364. [PubMed] [Google Scholar]
  8. Benedict W. F., Fung Y. K., Murphree A. L. The gene responsible for the development of retinoblastoma and osteosarcoma. Cancer. 1988 Oct 15;62(8 Suppl):1691–1694. doi: 10.1002/1097-0142(19881015)62:1+<1691::aid-cncr2820621306>3.0.co;2-5. [DOI] [PubMed] [Google Scholar]
  9. Benedict W. F., Murphree A. L., Banerjee A., Spina C. A., Sparkes M. C., Sparkes R. S. Patient with 13 chromosome deletion: evidence that the retinoblastoma gene is a recessive cancer gene. Science. 1983 Feb 25;219(4587):973–975. doi: 10.1126/science.6336308. [DOI] [PubMed] [Google Scholar]
  10. Bourne S. P., Patel K., Walsh F., Popham C. J., Coakham H. B., Kemshead J. T. A monoclonal antibody (ERIC-1), raised against retinoblastoma, that recognizes the neural cell adhesion molecule (NCAM) expressed on brain and tumours arising from the neuroectoderm. J Neurooncol. 1991 Apr;10(2):111–119. doi: 10.1007/BF00146871. [DOI] [PubMed] [Google Scholar]
  11. Cavenee W. K., Hansen M. F., Nordenskjold M., Kock E., Maumenee I., Squire J. A., Phillips R. A., Gallie B. L. Genetic origin of mutations predisposing to retinoblastoma. Science. 1985 Apr 26;228(4698):501–503. doi: 10.1126/science.3983638. [DOI] [PubMed] [Google Scholar]
  12. Cavenee W. K., Murphree A. L., Shull M. M., Benedict W. F., Sparkes R. S., Kock E., Nordenskjold M. Prediction of familial predisposition to retinoblastoma. N Engl J Med. 1986 May 8;314(19):1201–1207. doi: 10.1056/NEJM198605083141901. [DOI] [PubMed] [Google Scholar]
  13. Char D. H., Hedges T. R., 3rd, Norman D. Retinoblastoma. CT diagnosis. Ophthalmology. 1984 Nov;91(11):1347–1350. doi: 10.1016/s0161-6420(84)34143-4. [DOI] [PubMed] [Google Scholar]
  14. Char D. H., Wood I. S., Huhta K., Rand N., Morita C. T., Howes E. L., Jr Retinoblastoma: tissue culture lines and monoclonal antibody studies. Invest Ophthalmol Vis Sci. 1984 Jan;25(1):30–40. [PubMed] [Google Scholar]
  15. Co M. S., Queen C. Humanized antibodies for therapy. Nature. 1991 Jun 6;351(6326):501–502. doi: 10.1038/351501a0. [DOI] [PubMed] [Google Scholar]
  16. Coakham H. B., Garson J. A., Allan P. M., Harper E. I., Brownell B., Kemshead J. T., Lane E. B. Immunohistological diagnosis of central nervous system tumours using a monoclonal antibody panel. J Clin Pathol. 1985 Feb;38(2):165–173. doi: 10.1136/jcp.38.2.165. [DOI] [PMC free article] [PubMed] [Google Scholar]
  17. Coakham H. B., Garson J. A., Brownell B., Allan P. M., Harper E. I., Lane E. B., Kemshead J. T. Use of monoclonal antibody panel to identify malignant cells in cerebrospinal fluid. Lancet. 1984 May 19;1(8386):1095–1098. doi: 10.1016/s0140-6736(84)92508-x. [DOI] [PubMed] [Google Scholar]
  18. Coakham H. B., Richardson R. B., Davies A. G., Bourne S. P., Eckert H., Kemshead J. T. Neoplastic meningitis from a pineal tumour treated by antibody-guided irradiation via the intrathecal route. Br J Neurosurg. 1988;2(2):199–209. doi: 10.3109/02688698808992670. [DOI] [PubMed] [Google Scholar]
  19. Connors T. A. Antibody-directed enzyme prodrug therapy. Cancer Cells. 1990 Feb;2(2):56–57. [PubMed] [Google Scholar]
  20. Connors T. A. Has chemotherapy anywhere to go? Cancer Surv. 1989;8(3):693–705. [PubMed] [Google Scholar]
  21. Darbyshire P. J., Bourne S. P., Allan P. M., Berry J., Oakhill A., Kemshead J. T., Coakham H. B. The use of a panel of monoclonal antibodies in pediatric oncology. Cancer. 1987 Feb 15;59(4):726–730. doi: 10.1002/1097-0142(19870215)59:4<726::aid-cncr2820590411>3.0.co;2-v. [DOI] [PubMed] [Google Scholar]
  22. DeCaprio J. A., Ludlow J. W., Figge J., Shew J. Y., Huang C. M., Lee W. H., Marsilio E., Paucha E., Livingston D. M. SV40 large tumor antigen forms a specific complex with the product of the retinoblastoma susceptibility gene. Cell. 1988 Jul 15;54(2):275–283. doi: 10.1016/0092-8674(88)90559-4. [DOI] [PubMed] [Google Scholar]
  23. Donaldson S. S., Smith L. M. Retinoblastoma: biology, presentation, and current management. Oncology (Williston Park) 1989 Apr;3(4):45–52. [PubMed] [Google Scholar]
  24. Dyson N., Howley P. M., Münger K., Harlow E. The human papilloma virus-16 E7 oncoprotein is able to bind to the retinoblastoma gene product. Science. 1989 Feb 17;243(4893):934–937. doi: 10.1126/science.2537532. [DOI] [PubMed] [Google Scholar]
  25. Embleton M. J., Charleston A., Robins R. A., Pimm M. V., Baldwin R. W. Recombinant ricin toxin A chain cytotoxicity against carcinoembryonic antigen expressing tumour cells mediated by a bispecific monoclonal antibody and its potentiation by ricin toxin B chain. Br J Cancer. 1991 May;63(5):670–674. doi: 10.1038/bjc.1991.153. [DOI] [PMC free article] [PubMed] [Google Scholar]
  26. Epenetos A. A., Hooker G., Krausz T., Snook D., Bodmer W. F., Taylor-Papadimitriou J. Antibody-guided irradiation of malignant ascites in ovarian cancer: a new therapeutic method possessing specificity against cancer cells. Obstet Gynecol. 1986 Sep;68(3 Suppl):71S–74S. [PubMed] [Google Scholar]
  27. Epenetos A. A., Kosmas C. Monoclonal antibodies for imaging and therapy. Br J Cancer. 1989 Feb;59(2):152–155. doi: 10.1038/bjc.1989.32. [DOI] [PMC free article] [PubMed] [Google Scholar]
  28. Freedman J., Goldberg L. Incidence of retinoblastoma in the Bantu of South Africa. Br J Ophthalmol. 1976 Sep;60(9):655–656. doi: 10.1136/bjo.60.9.655. [DOI] [PMC free article] [PubMed] [Google Scholar]
  29. Gallie B. L., Squire J. A., Goddard A., Dunn J. M., Canton M., Hinton D., Zhu X. P., Phillips R. A. Mechanism of oncogenesis in retinoblastoma. Lab Invest. 1990 Apr;62(4):394–408. [PubMed] [Google Scholar]
  30. Girard B., Le Hoang P., D'Hermies F., Quere M. A., Rousselie F. Le rétinoblastome infiltrant diffus. J Fr Ophtalmol. 1989;12(5):369–381. [PubMed] [Google Scholar]
  31. Griegel S., Hong C., Frötschl R., Hülser D. F., Greger V., Horsthemke B., Rajewsky M. F. Newly established human retinoblastoma cell lines exhibit an "immortalized" but not an invasive phenotype in vitro. Int J Cancer. 1990 Jul 15;46(1):125–132. doi: 10.1002/ijc.2910460123. [DOI] [PubMed] [Google Scholar]
  32. Gullick W. J. Prevalence of aberrant expression of the epidermal growth factor receptor in human cancers. Br Med Bull. 1991 Jan;47(1):87–98. doi: 10.1093/oxfordjournals.bmb.a072464. [DOI] [PubMed] [Google Scholar]
  33. Hellström K. E., Hellström I. Oncogene-associated tumor antigens as targets for immunotherapy. FASEB J. 1989 Apr;3(6):1715–1722. doi: 10.1096/fasebj.3.6.2649402. [DOI] [PubMed] [Google Scholar]
  34. Herman M. M., Perentes E., Katsetos C. D., Darcel F., Frankfurter A., Collins V. P., Donoso L. A., Eng L. F., Marangos P. J., Wiechmann A. F. Neuroblastic differentiation potential of the human retinoblastoma cell lines Y-79 and WERI-Rb1 maintained in an organ culture system. An immunohistochemical, electron microscopic, and biochemical study. Am J Pathol. 1989 Jan;134(1):115–132. [PMC free article] [PubMed] [Google Scholar]
  35. Hungerford J. L. Recent advances in the understanding of retinoblastoma. Trans Ophthalmol Soc U K. 1985;104(Pt 8):832–835. [PubMed] [Google Scholar]
  36. Ito T., Qiu H., Collins J. A., Brill A. B., Johnson D. K., Griffin T. W. Preclinical assessments of 90Y-labeled C110 anti-carcinoembryonic antigen immunotoxin: a therapeutic immunoconjugate for human colon cancer. Cancer Res. 1991 Jan 1;51(1):255–260. [PubMed] [Google Scholar]
  37. Jiang Q., Lim R., Blodi F. C. Dual properties of cultured retinoblastoma cells: immunohistochemical characterization of neuronal and glial markers. Exp Eye Res. 1984 Aug;39(2):207–215. doi: 10.1016/0014-4835(84)90009-5. [DOI] [PubMed] [Google Scholar]
  38. Jonak Z. L., Kennett R. H., Bechtol K. B. Detection of neuroblastoma cells in human bone marrow using a combination of monoclonal antibodies. Hybridoma. 1982;1(4):349–368. doi: 10.1089/hyb.1.1982.1.349. [DOI] [PubMed] [Google Scholar]
  39. Karcioglu Z. A., Gordon R. A., Karcioglu G. L. Tumor seeding in ocular fine needle aspiration biopsy. Ophthalmology. 1985 Dec;92(12):1763–1767. doi: 10.1016/s0161-6420(85)34105-2. [DOI] [PubMed] [Google Scholar]
  40. Karcioglu Z. A., Haik B. G., Gordon R. A. Frozen section of the optic nerve in retinoblastoma surgery. Ophthalmology. 1988 May;95(5):674–676. doi: 10.1016/s0161-6420(88)33142-8. [DOI] [PubMed] [Google Scholar]
  41. Kayembe-Lubeji D. Retinoblastoma in Zaire. Trop Doct. 1990 Jan;20(1):38–38. doi: 10.1177/004947559002000113. [DOI] [PubMed] [Google Scholar]
  42. Kemshead J. T., Goldman A., Fritschy J., Malpas J. S., Pritchard J. Use of panels of monoclonal antibodies in the differential diagnosis of neuroblastoma and lymphoblastic disorders. Lancet. 1983 Jan 1;1(8314-5):12–15. doi: 10.1016/s0140-6736(83)91559-3. [DOI] [PubMed] [Google Scholar]
  43. Kemshead J. T., Walsh F., Pritchard J., Greaves M. Monoclonal antibody to ganglioside GQ discriminates between haemopoietic cells and infiltrating neuroblastoma tumour cells in bone marrow. Int J Cancer. 1981;27(4):447–452. doi: 10.1002/ijc.2910270405. [DOI] [PubMed] [Google Scholar]
  44. Kivelä T., Tarkkanen A., Virtanen I. Synaptophysin in the human retina and retinoblastoma. An immunohistochemical and Western blotting study. Invest Ophthalmol Vis Sci. 1989 Feb;30(2):212–219. [PubMed] [Google Scholar]
  45. Knudson A. G., Jr Mutation and cancer: statistical study of retinoblastoma. Proc Natl Acad Sci U S A. 1971 Apr;68(4):820–823. doi: 10.1073/pnas.68.4.820. [DOI] [PMC free article] [PubMed] [Google Scholar]
  46. Knudson A. G., Jr The genetics of childhood cancer. Cancer. 1975 Mar;35(3 Suppl):1022–1026. doi: 10.1002/1097-0142(197503)35:3+<1022::aid-cncr2820350726>3.0.co;2-a. [DOI] [PubMed] [Google Scholar]
  47. Kodilinye H. C. Retinoblastoma in Nigeria: problems of treatment. Am J Ophthalmol. 1967 Mar;63(3):469–481. doi: 10.1016/0002-9394(67)90246-2. [DOI] [PubMed] [Google Scholar]
  48. Kopelman J. E., McLean I. W., Rosenberg S. H. Multivariate analysis of risk factors for metastasis in retinoblastoma treated by enucleation. Ophthalmology. 1987 Apr;94(4):371–377. doi: 10.1016/s0161-6420(87)33436-0. [DOI] [PubMed] [Google Scholar]
  49. Kyritsis A. P., Tsokos M., Triche T. J., Chader G. J. Retinoblastoma--origin from a primitive neuroectodermal cell? Nature. 1984 Feb 2;307(5950):471–473. doi: 10.1038/307471a0. [DOI] [PubMed] [Google Scholar]
  50. Lee W. H., Bookstein R. E., Lee E. Y. Molecular biology of the human retinoblastoma gene. Immunol Ser. 1990;51:169–200. [PubMed] [Google Scholar]
  51. Lee Y. S., Bullard D. E., Zalutsky M. R., Coleman R. E., Wikstrand C. J., Friedman H. S., Colapinto E. V., Bigner D. D. Therapeutic efficacy of antiglioma mesenchymal extracellular matrix 131I-radiolabeled murine monoclonal antibody in a human glioma xenograft model. Cancer Res. 1988 Feb 1;48(3):559–566. [PubMed] [Google Scholar]
  52. Mach J. P., Pèlegrin A., Buchegger F. Imaging and therapy with monoclonal antibodies in non-hematopoietic tumors. Curr Opin Immunol. 1991 Oct;3(5):685–693. doi: 10.1016/0952-7915(91)90097-k. [DOI] [PubMed] [Google Scholar]
  53. Mafee M. F., Goldberg M. F., Cohen S. B., Gotsis E. D., Safran M., Chekuri L., Raofi B. Magnetic resonance imaging versus computed tomography of leukocoric eyes and use of in vitro proton magnetic resonance spectroscopy of retinoblastoma. Ophthalmology. 1989 Jul;96(7):965–976. doi: 10.1016/s0161-6420(89)32773-4. [DOI] [PubMed] [Google Scholar]
  54. Massuger L. F., Kenemans P., Claessens R. A., Verheijen R. H., Schijf C. P., Strijk S. P., Poels L. G., van Hoesel R. G., Corstens F. H. Immunoscintigraphy of ovarian cancer with indium-111-labeled OV-TL 3 F(ab')2 monoclonal antibody. J Nucl Med. 1990 Nov;31(11):1802–1810. [PubMed] [Google Scholar]
  55. McFall R. C., Sery T. W., Makadon M. Characterization of a new continuous cell line derived from a human retinoblastoma. Cancer Res. 1977 Apr;37(4):1003–1010. [PubMed] [Google Scholar]
  56. Merriam J. C., Lyon H. S., Char D. H. Toxicity of a monoclonal F(ab')2:ricin A conjugate for retinoblastoma in vitro. Cancer Res. 1984 Aug;44(8):3178–3183. [PubMed] [Google Scholar]
  57. Messmer E. P., Font R. L., Kirkpatrick J. B., Höpping W. Immunohistochemical demonstration of neuronal and astrocytic differentiation in retinoblastoma. Ophthalmology. 1985 Jan;92(1):167–173. doi: 10.1016/s0161-6420(85)34076-9. [DOI] [PubMed] [Google Scholar]
  58. Mirshahi M., Boucheix C., Dhermy P., Haye C., Faure J. P. Expression of the photoreceptor-specific S-antigen in human retinoblastoma. Cancer. 1986 Apr 15;57(8):1497–1500. doi: 10.1002/1097-0142(19860415)57:8<1497::aid-cncr2820570810>3.0.co;2-h. [DOI] [PubMed] [Google Scholar]
  59. Molnar M. L., Stefansson K., Marton L. S., Tripathi R. S., Molnar G. K. Immunohistochemistry of retinoblastomas in humans. Am J Ophthalmol. 1984 Mar;97(3):301–307. doi: 10.1016/0002-9394(84)90627-5. [DOI] [PubMed] [Google Scholar]
  60. Moseley R. P., Benjamin J. C., Ashpole R. D., Sullivan N. M., Bullimore J. A., Coakham H. B., Kemshead J. T. Carcinomatous meningitis: antibody-guided therapy with I-131 HMFG1. J Neurol Neurosurg Psychiatry. 1991 Mar;54(3):260–265. doi: 10.1136/jnnp.54.3.260. [DOI] [PMC free article] [PubMed] [Google Scholar]
  61. Muncaster M. M., Cohen B. L., Phillips R. A., Gallie B. L. Failure of RB1 to reverse the malignant phenotype of human tumor cell lines. Cancer Res. 1992 Feb 1;52(3):654–661. [PubMed] [Google Scholar]
  62. O'Brien J. M., Marcus D. M., Niffenegger A. S., Bernards R., Carpenter J. L., Windle J. J., Mellon P., Albert D. M. Trilateral retinoblastoma in transgenic mice. Trans Am Ophthalmol Soc. 1989;87:301–326. [PMC free article] [PubMed] [Google Scholar]
  63. Paganelli G., Malcovati M., Fazio F. Monoclonal antibody pretargetting techniques for tumour localization: the avidin-biotin system. International Workshop on Techniques for Amplification of Tumour Targetting. Nucl Med Commun. 1991 Mar;12(3):211–234. doi: 10.1097/00006231-199103000-00006. [DOI] [PubMed] [Google Scholar]
  64. Pizer B., Papanastassiou V., Hancock J., Cassano W., Coakham H., Kemshead J. A pilot study of monoclonal antibody targeted radiotherapy in the treatment of central nervous system leukaemia in children. Br J Haematol. 1991 Apr;77(4):466–472. doi: 10.1111/j.1365-2141.1991.tb08611.x. [DOI] [PubMed] [Google Scholar]
  65. Reid T. W., Albert D. M., Rabson A. S., Russell P., Craft J., Chu E. W., Tralka T. S., Wilcox J. L. Characteristics of an established cell line of retinoblastoma. J Natl Cancer Inst. 1974 Aug;53(2):347–360. doi: 10.1093/jnci/53.2.347. [DOI] [PubMed] [Google Scholar]
  66. Riechmann L., Clark M., Waldmann H., Winter G. Reshaping human antibodies for therapy. Nature. 1988 Mar 24;332(6162):323–327. doi: 10.1038/332323a0. [DOI] [PubMed] [Google Scholar]
  67. Ritz J., Pesando J. M., Notis-McConarty J., Schlossman S. F. Modulation of human acute lymphoblastic leukemia antigen induced by monoclonal antibody in vitro. J Immunol. 1980 Oct;125(4):1506–1514. [PubMed] [Google Scholar]
  68. Rodrigues M. M., Wiggert B., Shields J., Donoso L., Bardenstein D., Katz N., Friendly D., Chader G. Retinoblastoma. Immunohistochemistry and cell differentiation. Ophthalmology. 1987 Apr;94(4):378–387. doi: 10.1016/s0161-6420(87)33448-7. [DOI] [PubMed] [Google Scholar]
  69. Saleh R. A., Gross S., Cassano W., Gee A. Metastatic retinoblastoma successfully treated with immunomagnetic purged autologous bone marrow transplantation. Cancer. 1988 Dec 1;62(11):2301–2303. doi: 10.1002/1097-0142(19881201)62:11<2301::aid-cncr2820621107>3.0.co;2-s. [DOI] [PubMed] [Google Scholar]
  70. Sanders B. M., Draper G. J., Kingston J. E. Retinoblastoma in Great Britain 1969-80: incidence, treatment, and survival. Br J Ophthalmol. 1988 Aug;72(8):576–583. doi: 10.1136/bjo.72.8.576. [DOI] [PMC free article] [PubMed] [Google Scholar]
  71. Sasabe T., Inana G. Mechanism of suppression of malignancy in hybrids between Y79 retinoblastoma and NIH3T3 cells. Invest Ophthalmol Vis Sci. 1991 Jun;32(7):2011–2019. [PubMed] [Google Scholar]
  72. Scheidler J., Leinsinger G., Kirsch C. M., Scheiffarth O. F., Stefani F. H., Riedel K. G. Immunoimaging of choroidal melanoma: assessment of its diagnostic accuracy and limitations in 101 cases. Br J Ophthalmol. 1992 Aug;76(8):457–460. doi: 10.1136/bjo.76.8.457. [DOI] [PMC free article] [PubMed] [Google Scholar]
  73. Schlom J., Milenic D. E., Roselli M., Colcher D., Bird R., Johnson S., Hardman K. D., Guadagni F., Greiner J. W. New concepts in monoclonal antibody based radioimmunodiagnosis and radioimmunotherapy of carcinoma. Int J Rad Appl Instrum B. 1991;18(4):425–435. doi: 10.1016/0883-2897(91)90070-2. [DOI] [PubMed] [Google Scholar]
  74. Seeger R. C., Danon Y. L., Rayner S. A., Hoover F. Definition of a Thy-1 determinant on human neuroblastoma, glioma, sarcoma, and teratoma cells with a monoclonal antibody. J Immunol. 1982 Feb;128(2):983–989. [PubMed] [Google Scholar]
  75. Shields J. A., Shields C. L., Donoso L. A., Lieb W. Current treatment of retinoblastoma. Trans Pa Acad Ophthalmol Otolaryngol. 1989;41:818–822. [PubMed] [Google Scholar]
  76. Shields J. A., Shields C. L., Parsons H. M. Differential diagnosis of retinoblastoma. Retina. 1991;11(2):232–243. [PubMed] [Google Scholar]
  77. Sikora K., Smedley H., Thorpe P. Tumour imaging and drug targeting. Br Med Bull. 1984 Jul;40(3):233–239. doi: 10.1093/oxfordjournals.bmb.a071983. [DOI] [PubMed] [Google Scholar]
  78. Stevenson K. E., Hungerford J., Garner A. Local extraocular extension of retinoblastoma following intraocular surgery. Br J Ophthalmol. 1989 Sep;73(9):739–742. doi: 10.1136/bjo.73.9.739. [DOI] [PMC free article] [PubMed] [Google Scholar]
  79. Sun X. L., Yokoyama T., Minoda K., Sakuma A. Immunohistochemical studies of retinoblastoma. Jpn J Ophthalmol. 1990;34(2):149–157. [PubMed] [Google Scholar]
  80. Tarlton J. F., Easty D. L. Immunohistological characterisation of retinoblastoma and related ocular tissue. Br J Ophthalmol. 1990 Mar;74(3):144–149. doi: 10.1136/bjo.74.3.144. [DOI] [PMC free article] [PubMed] [Google Scholar]
  81. Vitetta E. S., Krolick K. A., Miyama-Inaba M., Cushley W., Uhr J. W. Immunotoxins: a new approach to cancer therapy. Science. 1983 Feb 11;219(4585):644–650. doi: 10.1126/science.6218613. [DOI] [PubMed] [Google Scholar]
  82. Vrabec T., Arbizo V., Adamus G., McDowell J. H., Hargrave P. A., Donoso L. A. Rod cell-specific antigens in retinoblastoma. Arch Ophthalmol. 1989 Jul;107(7):1061–1063. doi: 10.1001/archopht.1989.01070020123044. [DOI] [PubMed] [Google Scholar]
  83. White L. Chemotherapy in retinoblastoma: current status and future directions. Am J Pediatr Hematol Oncol. 1991 Summer;13(2):189–201. [PubMed] [Google Scholar]
  84. Whyte P., Buchkovich K. J., Horowitz J. M., Friend S. H., Raybuck M., Weinberg R. A., Harlow E. Association between an oncogene and an anti-oncogene: the adenovirus E1A proteins bind to the retinoblastoma gene product. Nature. 1988 Jul 14;334(6178):124–129. doi: 10.1038/334124a0. [DOI] [PubMed] [Google Scholar]
  85. Zanin D. E., van Dongen A., Hoefnagel C. A., Bruning P. F. Radioimmunoscintigraphy using iodine-131-anti-CEA monoclonal antibodies and thallium-201 scintigraphy in medullary thyroid carcinoma: a case report. J Nucl Med. 1990 Nov;31(11):1854–1855. [PubMed] [Google Scholar]

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