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. 1994 Mar;78(3):206–208. doi: 10.1136/bjo.78.3.206

The treatment and follow up of adult chlamydial ophthalmia.

F Carta 1, S Zanetti 1, A Pinna 1, M Sotgiu 1, G Fadda 1
PMCID: PMC504737  PMID: 8148336

Abstract

Sixty two patients diagnosed as having adult chlamydial ophthalmia were treated with oral doxycycline and roxithromycin in association and tetracycline eye wash for 2 weeks. Chlamydial ophthalmia was diagnosed by laboratory detection of the micro-organism in ocular specimens using direct immunofluorescent monoclonal antibody staining for Chlamydia trachomatis, chlamydial culture in cycloheximide treated McCoy cells, and Giemsa staining. An immunoenzymatic method for detection of specific IgG and IgA in patients' serum was used as an additional test to confirm the diagnosis. All patients were reexamined 3 weeks after completing their course of antibiotics and in the case of persistent infection a further course of treatment was given. With this treatment regimen 48 out of 62 patients (77.4%) were cured after three courses. Because of the risks of an inadequate response to therapy, we recommend a proper post-treatment follow up in all patients with chlamydial eye infections.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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