Skip to main content
The British Journal of Ophthalmology logoLink to The British Journal of Ophthalmology
. 1994 May;78(5):359–362. doi: 10.1136/bjo.78.5.359

Pattern electroretinogram and automated perimetry in patients with glaucoma and ocular hypertension.

C Neoh 1, S B Kaye 1, M Brown 1, A M Ansons 1, P Wishart 1
PMCID: PMC504787  PMID: 8025069

Abstract

To determine whether the pattern electroretinogram can improve the objectivity of visual field assessment, 39 patients with glaucoma and ocular hypertension were studied. This was to establish whether there is a correlation between the pattern electroretinogram and the global indices (mean deviation and corrected pattern standard deviation) provided by automated perimetry using the Humphrey visual field analyser. A significant correlation was found between the amplitude of the P50 + N95 wave of the pattern electroretinogram and the mean deviation and corrected pattern standard deviation components of the visual field. The larger the deviation from normal of these indices, particularly the corrected pattern standard deviation, the smaller the amplitude of the pattern electroretinogram. This correlation between the pattern electroretinogram and visual field indices provides an additional measure of confidence when interpreting equivocal results of automated perimetry.

Full text

PDF
359

Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. Arden G. B., Carter R. M., Hogg C., Siegel I. M., Margolis S. A gold foil electrode: extending the horizons for clinical electroretinography. Invest Ophthalmol Vis Sci. 1979 Apr;18(4):421–426. [PubMed] [Google Scholar]
  2. Bach M., Hiss P., Röver J. Check-size specific changes of pattern electroretinogram in patients with early open-angle glaucoma. Doc Ophthalmol. 1988 Jul;69(3):315–322. doi: 10.1007/BF00154412. [DOI] [PubMed] [Google Scholar]
  3. Berninger T. A., Arden G. B., Hogg C. R., Frumkes T. Separable evoked retinal and cortical potentials from each major visual pathway: preliminary results. Br J Ophthalmol. 1989 Jul;73(7):502–511. doi: 10.1136/bjo.73.7.502. [DOI] [PMC free article] [PubMed] [Google Scholar]
  4. Dawson W. W., Maida T. M., Rubin M. L. Human pattern-evoked retinal responses are altered by optic atrophy. Invest Ophthalmol Vis Sci. 1982 Jun;22(6):796–803. [PubMed] [Google Scholar]
  5. Drance S. M., Airaksinen P. J., Price M., Schulzer M., Douglas G. R., Tansley B. W. The correlation of functional and structural measurements in glaucoma patients and normal subjects. Am J Ophthalmol. 1986 Nov 15;102(5):612–616. doi: 10.1016/0002-9394(86)90533-7. [DOI] [PubMed] [Google Scholar]
  6. Fiorentini A., Maffei L., Pirchio M., Spinelli D., Porciatti V. The ERG in response to alternating gratings in patients with diseases of the peripheral visual pathway. Invest Ophthalmol Vis Sci. 1981 Sep;21(3):490–493. [PubMed] [Google Scholar]
  7. Heijl A., Lindgren A., Lindgren G. Test-retest variability in glaucomatous visual fields. Am J Ophthalmol. 1989 Aug 15;108(2):130–135. doi: 10.1016/0002-9394(89)90006-8. [DOI] [PubMed] [Google Scholar]
  8. Hess R. F., Baker C. L., Jr Human pattern-evoked electroretinogram. J Neurophysiol. 1984 May;51(5):939–951. doi: 10.1152/jn.1984.51.5.939. [DOI] [PubMed] [Google Scholar]
  9. Holder G. E. Significance of abnormal pattern electroretinography in anterior visual pathway dysfunction. Br J Ophthalmol. 1987 Mar;71(3):166–171. doi: 10.1136/bjo.71.3.166. [DOI] [PMC free article] [PubMed] [Google Scholar]
  10. Katz J., Sommer A., Gaasterland D. E., Anderson D. R. Comparison of analytic algorithms for detecting glaucomatous visual field loss. Arch Ophthalmol. 1991 Dec;109(12):1684–1689. doi: 10.1001/archopht.1991.01080120068028. [DOI] [PubMed] [Google Scholar]
  11. Mafei L., Fiorentini A. Electroretinographic responses to alternating gratings before and after section of the optic nerve. Science. 1981 Feb 27;211(4485):953–955. doi: 10.1126/science.7466369. [DOI] [PubMed] [Google Scholar]
  12. May J. G., Ralston J. V., Reed J. L., Van Dyk H. J. Loss in pattern-elicited electroretinograms in optic nerve dysfunction. Am J Ophthalmol. 1982 Apr;93(4):418–422. doi: 10.1016/0002-9394(82)90131-3. [DOI] [PubMed] [Google Scholar]
  13. O'Donaghue E., Arden G. B., O'Sullivan F., Falcão-Reis F., Moriarty B., Hitchings R. A., Spilleers W., Hogg C., Weinstein G. The pattern electroretinogram in glaucoma and ocular hypertension. Br J Ophthalmol. 1992 Jul;76(7):387–394. doi: 10.1136/bjo.76.7.387. [DOI] [PMC free article] [PubMed] [Google Scholar]
  14. Ohta H., Tamura T., Kawasaki K., Yonemura D. [Negative wave in human pattern ERG and its suppression in glaucoma]. Nippon Ganka Gakkai Zasshi. 1986 Jun;90(6):882–887. [PubMed] [Google Scholar]
  15. Pfeiffer N., Birkner-Binder D., Bach M. Das Muster-ERG bei okulärer Hypertension und Glaukom. Einfluss von Karogrösse, Kontrast und retinaler Exzentrizität. Fortschr Ophthalmol. 1991;88(6):815–818. [PubMed] [Google Scholar]
  16. Porciatti V., Falsini B., Brunori S., Colotto A., Moretti G. Pattern electroretinogram as a function of spatial frequency in ocular hypertension and early glaucoma. Doc Ophthalmol. 1987 Mar;65(3):349–355. doi: 10.1007/BF00149941. [DOI] [PubMed] [Google Scholar]
  17. Wanger P., Persson H. E. Pattern-reversal electroretinograms from normotensive, hypertensive and glaucomatous eyes. Ophthalmologica. 1987;195(4):205–208. doi: 10.1159/000309814. [DOI] [PubMed] [Google Scholar]
  18. Wanger P., Persson H. E. Pattern-reversal electroretinograms in unilateral glaucoma. Invest Ophthalmol Vis Sci. 1983 Jun;24(6):749–753. [PubMed] [Google Scholar]
  19. Watanabe I., Iijima H., Tsukahara S. The pattern electroretinogram in glaucoma: an evaluation by relative amplitude from the Bjerrum area. Br J Ophthalmol. 1989 Feb;73(2):131–135. doi: 10.1136/bjo.73.2.131. [DOI] [PMC free article] [PubMed] [Google Scholar]
  20. Weinstein G. W., Arden G. B., Hitchings R. A., Ryan S., Calthorpe C. M., Odom J. V. The pattern electroretinogram (PERG) in ocular hypertension and glaucoma. Arch Ophthalmol. 1988 Jul;106(7):923–928. doi: 10.1001/archopht.1988.01060140069027. [DOI] [PubMed] [Google Scholar]
  21. van den Berg T. J., Riemslag F. C., de Vos G. W., Verduyn Lunel H. F. Pattern ERG and glaucomatous visual field defects. Doc Ophthalmol. 1986 Jan 15;61(3-4):335–341. doi: 10.1007/BF00142361. [DOI] [PubMed] [Google Scholar]

Articles from The British Journal of Ophthalmology are provided here courtesy of BMJ Publishing Group

RESOURCES