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. 1994 Jul;78(7):542–545. doi: 10.1136/bjo.78.7.542

Relation between iridopathy and retinopathy in diabetes.

F Bandello 1, R Brancato 1, R Lattanzio 1, M Galdini 1, B Falcomatà 1
PMCID: PMC504860  PMID: 7918265

Abstract

In order to assess the relation between diabetic iridopathy (DI) and retinopathy (DR), 225 eyes of 117 diabetics with clear media were evaluated. Each patient underwent iris and retinal fluorescein angiography, which was used to classify DI and DR. DI was classified as: absence of DI; non-proliferative DI; proliferative DI; neovascular glaucoma. DR was classified as: absence of DR; background DR; pre-proliferative DR; proliferative DR. The sensitivity of iris fluorescein angiography in assessing DR was 44.5%, the specificity 88%, the positive predictive value 92.8%, and the negative value 31.2%. In pre-proliferative and proliferative DR, fluoroiridographic detection of iris neovessels gave a sensitivity of 56% and a specificity of 100%. The positive predictive value was 100% and the negative value 65%. In conclusion, iris fluorescein angiography yields valuable information on DR and is a helpful basis for avoiding complications when scheduling eyes with dioptric media opacities for surgery.

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Selected References

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  1. Aiello L. M., Wand M., Liang G. Neovascular glaucoma and vitreous hemorrhage following cataract surgery in patients with diabetes mellitus. Ophthalmology. 1983 Jul;90(7):814–820. doi: 10.1016/s0161-6420(83)34498-5. [DOI] [PubMed] [Google Scholar]
  2. Algvere P., Kornacki B. Fluorescein angiography of the iris. A correlation of microangiopathy in the iris and retina. Acta Ophthalmol (Copenh) 1978 Oct;56(5):803–816. doi: 10.1111/j.1755-3768.1978.tb06645.x. [DOI] [PubMed] [Google Scholar]
  3. Apple D. J., Craythorn J. M., Olson R. J., Little L. E., Lyman J. B., Reidy J. J., Loftfield K. Anterior segment complications and neovascular glaucoma following implantation of a posterior chamber intraocular lens. Ophthalmology. 1984 Apr;91(4):403–419. doi: 10.1016/s0161-6420(84)34290-7. [DOI] [PubMed] [Google Scholar]
  4. Baggesen L. H. Fluorescence angiography of the iris in diabetics and non-diabetics. Acta Ophthalmol (Copenh) 1969;47(3):449–460. doi: 10.1111/j.1755-3768.1969.tb08131.x. [DOI] [PubMed] [Google Scholar]
  5. Bandello F., Brancato R., Lattanzio R., Falcomatà B., Malegori A. Biomicroscopy versus fluorescein angiography of the iris in the detection of diabetic iridopathy. Graefes Arch Clin Exp Ophthalmol. 1993 Aug;231(8):444–448. doi: 10.1007/BF02044229. [DOI] [PubMed] [Google Scholar]
  6. Blankenship G. W., Machemer R. Pars plana vitrectomy for the management of severe diabetic retinopathy: an analysis of results five years following surgery. Ophthalmology. 1978 Jun;85(6):553–559. doi: 10.1016/s0161-6420(78)35639-6. [DOI] [PubMed] [Google Scholar]
  7. Blankenship G. Preoperative iris rubeosis and diabetic vitrectomy results. Ophthalmology. 1980 Mar;87(3):176–182. doi: 10.1016/s0161-6420(80)35255-x. [DOI] [PubMed] [Google Scholar]
  8. Bonnet M., Jourdain M., Francoz-Taillanter N. Corrélation néovaisseaux papillaires - rubeosis iridis. J Fr Ophtalmol. 1981;4(5):405–410. [PubMed] [Google Scholar]
  9. Brancato R., Leoni G., Trabucchi G., Lakidi E., Bulloni M. Contact transscleral irradiation of the human chorioretina with continuous-wave Nd:YAG laser. Ophthalmic Res. 1989;21(1):1–7. doi: 10.1159/000266760. [DOI] [PubMed] [Google Scholar]
  10. Cunliffe I. A., Flanagan D. W., George N. D., Aggarwaal R. J., Moore A. T. Extracapsular cataract surgery with lens implantation in diabetics with and without proliferative retinopathy. Br J Ophthalmol. 1991 Jan;75(1):9–12. doi: 10.1136/bjo.75.1.9. [DOI] [PMC free article] [PubMed] [Google Scholar]
  11. Demeler U., Sautter H. Irisangiographische Untersuchungen bei Patienten mit Diabetes Mellitus. Adv Ophthalmol. 1978;36:233–244. [PubMed] [Google Scholar]
  12. Ehrenberg M., McCuen B. W., 2nd, Schindler R. H., Machemer R. Rubeosis iridis: preoperative iris fluorescein angiography and periocular steroids. Ophthalmology. 1984 Apr;91(4):321–325. doi: 10.1016/s0161-6420(84)34292-0. [DOI] [PubMed] [Google Scholar]
  13. Friedburg D., Wigger H., Schultheiss K. Fluoreszenzangiographie der Iris bei Diabetikern. Klin Monbl Augenheilkd. 1973 Feb;162(2):218–223. [PubMed] [Google Scholar]
  14. Jaffe G. J., Burton T. C. Progression of nonproliferative diabetic retinopathy following cataract extraction. Arch Ophthalmol. 1988 Jun;106(6):745–749. doi: 10.1001/archopht.1988.01060130815029. [DOI] [PubMed] [Google Scholar]
  15. Jensen V. A., Lundbaek K. Fluorescence angiography of the iris in recent and long-term diabetes. Diabetologia. 1968 Jun;4(3):161–163. doi: 10.1007/BF01219437. [DOI] [PubMed] [Google Scholar]
  16. Laatikainen L. Development and classification of rubeosis iridis in diabetic eye disease. Br J Ophthalmol. 1979 Mar;63(3):150–156. doi: 10.1136/bjo.63.3.150. [DOI] [PMC free article] [PubMed] [Google Scholar]
  17. Levin M. L., Kincaid M. C., Eifler C. W., Holt J. E., Speights J. W., O'Connor P. S. Effect of cataract surgery and intraocular lenses on diabetic retinopathy. J Cataract Refract Surg. 1988 Nov;14(6):642–649. doi: 10.1016/s0886-3350(88)80032-4. [DOI] [PubMed] [Google Scholar]
  18. Lewis M. L. Iris fluorescein angiography. Dev Ophthalmol. 1981;2:282–285. doi: 10.1159/000395334. [DOI] [PubMed] [Google Scholar]
  19. Pavese T., Insler M. S. Effects of extracapsular cataract extraction with posterior chamber lens implantation on the development of neovascular glaucoma in diabetics. J Cataract Refract Surg. 1987 Mar;13(2):197–201. doi: 10.1016/s0886-3350(87)80135-9. [DOI] [PubMed] [Google Scholar]
  20. Poliner L. S., Christianson D. J., Escoffery R. F., Kolker A. E., Gordon M. E. Neovascular glaucoma after intracapsular and extracapsular cataract extraction in diabetic patients. Am J Ophthalmol. 1985 Nov 15;100(5):637–643. doi: 10.1016/0002-9394(85)90617-8. [DOI] [PubMed] [Google Scholar]
  21. Pollack A., Dotan S., Oliver M. Course of diabetic retinopathy following cataract surgery. Br J Ophthalmol. 1991 Jan;75(1):2–8. doi: 10.1136/bjo.75.1.2. [DOI] [PMC free article] [PubMed] [Google Scholar]
  22. Pollack A., Dotan S., Oliver M. Progression of diabetic retinopathy after cataract extraction. Br J Ophthalmol. 1991 Sep;75(9):547–551. doi: 10.1136/bjo.75.9.547. [DOI] [PMC free article] [PubMed] [Google Scholar]
  23. Prasad P., Setna P. H., Dunne J. A. Accelerated ocular neovascularisation in diabetics following posterior chamber lens implantation. Br J Ophthalmol. 1990 May;74(5):313–314. doi: 10.1136/bjo.74.5.313. [DOI] [PMC free article] [PubMed] [Google Scholar]
  24. Rice T. A., Michels R. G., Maguire M. G., Rice E. F. The effect of lensectomy on the incidence of iris neovascularization and neovascular glaucoma after vitrectomy for diabetic retinopathy. Am J Ophthalmol. 1983 Jan;95(1):1–11. doi: 10.1016/0002-9394(83)90328-8. [DOI] [PubMed] [Google Scholar]
  25. Ruiz R. S., Saatci O. A. Posterior chamber intraocular lens implantation in eyes with inactive and active proliferative diabetic retinopathy. Am J Ophthalmol. 1991 Feb 15;111(2):158–162. doi: 10.1016/s0002-9394(14)72253-6. [DOI] [PubMed] [Google Scholar]
  26. Sebestyen J. G. Intraocular lenses and diabetes mellitus. Am J Ophthalmol. 1986 Apr 15;101(4):425–428. doi: 10.1016/0002-9394(86)90640-9. [DOI] [PubMed] [Google Scholar]
  27. Vannas A. Fluorescein angiography of the vessels of the iris in pseudoexfoliation of the lens capsule, capsular glaucoma and some other forms of glaucoma. Acta Ophthalmol Suppl. 1969;105:1–75. [PubMed] [Google Scholar]

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