Skip to main content
NCBI home page
The British Journal of Ophthalmology logoLink to The British Journal of Ophthalmology
. 1994 Aug;78(8):615–617. doi: 10.1136/bjo.78.8.615

Peripheral retinal vasculature in normal Jamaican children.

A Penman 1, J F Talbot 1, E L Chuang 1, A C Bird 1, G R Serjeant 1
PMCID: PMC504885  PMID: 7918288

Abstract

A prospective study of the peripheral retinal vasculature in a Jamaican cohort of subjects with sickle cell disease has been in progress over a period of 12 years using fluorescein angiography. Various vascular patterns were identified but their significance was unclear since no comparable records were available in subjects of a similar age with normal (AA) haemoglobin genotype. Fluorescein retinal angioscopy and angiography have been performed in 76 haemoglobin AA controls participating in the cohort study. The peripheral retinal capillary bed could be seen and photographed in a limited portion of the temporal peripheral fundus in a majority of this group, and there was considerable variation in the vascular pattern which could be characterised. These observations allow deviations from normal to be identified in the retinal vasculature in subjects with sickle cell disease.

Full text

PDF
615

Images in this article

616Image
on p.616
616Image
on p.616
616Image
on p.616
616Image
on p.616
617Image
on p.617

Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. Archer D. B. Retinal neovascularization. Trans Ophthalmol Soc U K. 1983;103(Pt 1):2–27. [PubMed] [Google Scholar]
  2. Asdourian G. K., Goldberg M. F. The angiographic pattern of the peripheral retinal vasculature. Arch Ophthalmol. 1979 Dec;97(12):2316–2318. doi: 10.1001/archopht.1979.01020020532003. [DOI] [PubMed] [Google Scholar]
  3. Ashton N. Oxygen and the growth and development of retinal vessels. In vivo and in vitro studies. The XX Francis I. Proctor Lecture. Am J Ophthalmol. 1966 Sep;62(3):412–435. doi: 10.1016/0002-9394(66)91322-5. [DOI] [PubMed] [Google Scholar]
  4. COGAN D. G. DEVELOPMENT AND SENESCENCE OF THE HUMAN RETINAL VASCULATURE. Trans Ophthalmol Soc U K. 1963;83:465–489. [PubMed] [Google Scholar]
  5. Garner A. Ocular angiogenesis. Int Rev Exp Pathol. 1986;28:249–306. [PubMed] [Google Scholar]
  6. NILAUSEN K. The vasoformative tissue in the foetal retina with particular reference to the histochemical demonstration of its alkaline phosphatase activity. Acta Ophthalmol (Copenh) 1958;36(1):65–70. doi: 10.1111/j.1755-3768.1958.tb02260.x. [DOI] [PubMed] [Google Scholar]
  7. Serjeant B. E., Forbes M., Williams L. L., Serjeant G. R. Screening cord bloods for detection of sickle cell disease in Jamaica. Clin Chem. 1974 Jun;20(6):666–669. [PubMed] [Google Scholar]
  8. Serjeant G. R., Grandison Y., Lowrie Y., Mason K., Phillips J., Serjeant B. E., Vaidya S. The development of haematological changes in homozygous sickle cell disease: a cohort study from birth to 6 years. Br J Haematol. 1981 Aug;48(4):533–543. doi: 10.1111/j.1365-2141.1981.tb02750.x. [DOI] [PubMed] [Google Scholar]
  9. Talbot J. F., Bird A. C., Maude G. H., Acheson R. W., Moriarty B. J., Serjeant G. R. Sickle cell retinopathy in Jamaican children: further observations from a cohort study. Br J Ophthalmol. 1988 Oct;72(10):727–732. doi: 10.1136/bjo.72.10.727. [DOI] [PMC free article] [PubMed] [Google Scholar]
  10. Talbot J. F., Bird A. C., Serjeant G. R., Hayes R. J. Sickle cell retinopathy in young children in Jamaica. Br J Ophthalmol. 1982 Mar;66(3):149–154. doi: 10.1136/bjo.66.3.149. [DOI] [PMC free article] [PubMed] [Google Scholar]

Articles from The British Journal of Ophthalmology are provided here courtesy of BMJ Publishing Group

RESOURCES