Abstract
The purpose of this study was to determine the prevalence of retinal disease in a group of patients with AIDS in Malawi. Indirect ophthalmoscopy was performed on 99 patients with AIDS who were admitted consecutively to a medical ward at a central hospital. Necrotising retinitis was present in one eye of one patient examined. Non-infectious retinopathy was present in 13%. Retinitis is less common in AIDS patients from Africa compared with those from developed countries; it is believed that most patients die before acquiring it. Non-infectious retinopathy may also be less common.
Full text
PDF
Selected References
These references are in PubMed. This may not be the complete list of references from this article.
- De Cock K. M., Soro B., Coulibaly I. M., Lucas S. B. Tuberculosis and HIV infection in sub-Saharan Africa. JAMA. 1992 Sep 23;268(12):1581–1587. doi: 10.1001/jama.268.12.1581. [DOI] [PubMed] [Google Scholar]
- De Cock K. The new tuberculosis. Afr Health. 1994 Mar;16(3):8–10. [PubMed] [Google Scholar]
- Freeman W. R., Chen A., Henderly D. E., Levine A. M., Luttrull J. K., Urrea P. T., Arthur J., Rasheed S., Cohen J. L., Neuberg D. Prevalence and significance of acquired immunodeficiency syndrome-related retinal microvasculopathy. Am J Ophthalmol. 1989 Mar 15;107(3):229–235. doi: 10.1016/0002-9394(89)90304-8. [DOI] [PubMed] [Google Scholar]
- Gilks C. F. The clinical challenge of the HIV epidemic in the developing world. Lancet. 1993 Oct 23;342(8878):1037–1039. doi: 10.1016/0140-6736(93)92885-w. [DOI] [PubMed] [Google Scholar]
- Holland G. N., Pepose J. S., Pettit T. H., Gottlieb M. S., Yee R. D., Foos R. Y. Acquired immune deficiency syndrome. Ocular manifestations. Ophthalmology. 1983 Aug;90(8):859–873. doi: 10.1016/s0161-6420(83)80009-8. [DOI] [PubMed] [Google Scholar]
- Kestelyn P., Van de Perre P., Rouvroy D., Lepage P., Bogaerts J., Nzaramba D., Clumeck N. A prospective study of the ophthalmologic findings in the acquired immune deficiency syndrome in Africa. Am J Ophthalmol. 1985 Aug 15;100(2):230–238. doi: 10.1016/0002-9394(85)90787-1. [DOI] [PubMed] [Google Scholar]
- Margolis T. P., Lowder C. Y., Holland G. N., Spaide R. F., Logan A. G., Weissman S. S., Irvine A. R., Josephberg R., Meisler D. M., O'Donnell J. J. Varicella-zoster virus retinitis in patients with the acquired immunodeficiency syndrome. Am J Ophthalmol. 1991 Aug 15;112(2):119–131. doi: 10.1016/s0002-9394(14)76690-5. [DOI] [PubMed] [Google Scholar]
- Mukadi Y., Perriëns J. H., St Louis M. E., Brown C., Prignot J., Willame J. C., Pouthier F., Kaboto M., Ryder R. W., Portaels F. Spectrum of immunodeficiency in HIV-1-infected patients with pulmonary tuberculosis in Zaire. Lancet. 1993 Jul 17;342(8864):143–146. doi: 10.1016/0140-6736(93)91346-n. [DOI] [PubMed] [Google Scholar]
- Pepose J. S., Holland G. N., Nestor M. S., Cochran A. J., Foos R. Y. Acquired immune deficiency syndrome. Pathogenic mechanisms of ocular disease. Ophthalmology. 1985 Apr;92(4):472–484. doi: 10.1016/s0161-6420(85)34008-3. [DOI] [PubMed] [Google Scholar]
- Peters B. S., Beck E. J., Anderson S., Coleman D., Coker R., Main J., Migdal C., Harris J. R., Pinching A. J. Cytomegalovirus infection in AIDS. Patterns of disease, response to therapy and trends in survival. J Infect. 1991 Sep;23(2):129–137. doi: 10.1016/0163-4453(91)91987-9. [DOI] [PubMed] [Google Scholar]
- Tudor-Williams G. Early diagnosis of vertically acquired HIV-1 infection. AIDS. 1991 Jan;5(1):103–105. doi: 10.1097/00002030-199101000-00017. [DOI] [PubMed] [Google Scholar]
- Whittle H., Egboga A., Todd J., Corrah T., Wilkins A., Demba E., Morgan G., Rolfe M., Berry N., Tedder R. Clinical and laboratory predictors of survival in Gambian patients with symptomatic HIV-1 or HIV-2 infection. AIDS. 1992 Jul;6(7):685–689. doi: 10.1097/00002030-199207000-00011. [DOI] [PubMed] [Google Scholar]