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. Author manuscript; available in PMC: 2016 Oct 21.
Published in final edited form as: Oncogene. 2016 Apr 4;35(42):5480–5488. doi: 10.1038/onc.2016.91

Figure 6. Methylation levels of mir-124 genes correlate with SMOX expression in gastritis patients at various stages of disease.

Figure 6

In A, B, and C, generalized linear models were used to analyze the relationships between mir-124 promoter methylation and SMOX expression in the human gastric biopsies from both high- and low-risk regions combined. Regression plots present SMOX immunohistochemistry staining scores versus the percent methylation of mir-124-1, -2, or -3 (black dots: low-risk region patients; red dots: high-risk region patients; patients within the top and bottom 10th percentiles of mir-124 methylation were excluded from the plots but included in the multivariate analyses and calculations of p values). In D, the mean SMOX staining scores at the 10th and 90th percentiles of mir-124 methylation (at each locus) are presented with error bars indicating 95% confidence intervals.