Skip to main content
The British Journal of Ophthalmology logoLink to The British Journal of Ophthalmology
. 1995 Feb;79(2):144–149. doi: 10.1136/bjo.79.2.144

Photocoagulation treatment for clinically significant radiation macular oedema.

J L Kinyoun 1, R W Zamber 1, B S Lawrence 1, W E Barlow 1, A M Arnold 1
PMCID: PMC505045  PMID: 7696234

Abstract

Macular oedema is a leading cause of vision loss in patients with radiation retinopathy. In an effort to find an effective treatment for this vision threatening complication, 12 eyes (eight patients) were treated with photocoagulation for clinically significant radiation macular oedema (CSRMO) defined as central macular thickening, exudates threatening the macular centre, or one disc area of thickening in the macula. Median visual acuity improved from 20/100 preoperatively to 20/90 at the initial postoperative examination (mean follow up 5 months) and to 20/75 at the final postoperative examination (mean follow up 39 months). At the final postoperative examination, visual acuity had improved in eight (67%) eyes and six (50%) eyes had complete resolution of the CSRMO; two (17%) other eyes had improved anatomically in that fewer CSRMO criteria were present. These results suggest that macular photocoagulation is effective in decreasing macular oedema and improving vision in eyes with CSRMO.

Full text

PDF
144

Images in this article

Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. Amoaku W. M., Archer D. B. Fluorescein angiographic features, natural course and treatment of radiation retinopathy. Eye (Lond) 1990;4(Pt 5):657–667. doi: 10.1038/eye.1990.93. [DOI] [PubMed] [Google Scholar]
  2. Archer D. B. Doyne Lecture. Responses of retinal and choroidal vessels to ionising radiation. Eye (Lond) 1993;7(Pt 1):1–13. doi: 10.1038/eye.1993.3. [DOI] [PubMed] [Google Scholar]
  3. Brown G. C., Shields J. A., Sanborn G., Augsburger J. J., Savino P. J., Schatz N. J. Radiation optic neuropathy. Ophthalmology. 1982 Dec;89(12):1489–1493. doi: 10.1016/s0161-6420(82)34612-6. [DOI] [PubMed] [Google Scholar]
  4. Egbert P. R., Fajardo L. F., Donaldson S. S., Moazed K. Posterior ocular abnormalities after irradiation for retinoblastoma: a histopathological study. Br J Ophthalmol. 1980 Sep;64(9):660–665. doi: 10.1136/bjo.64.9.660. [DOI] [PMC free article] [PubMed] [Google Scholar]
  5. Guyer D. R., Mukai S., Egan K. M., Seddon J. M., Walsh S. M., Gragoudas E. S. Radiation maculopathy after proton beam irradiation for choroidal melanoma. Ophthalmology. 1992 Aug;99(8):1278–1285. doi: 10.1016/s0161-6420(92)31832-9. [DOI] [PubMed] [Google Scholar]
  6. Hidayat A. A., Fine B. S. Diabetic choroidopathy. Light and electron microscopic observations of seven cases. Ophthalmology. 1985 Apr;92(4):512–522. [PubMed] [Google Scholar]
  7. Kinyoun J. L., Chittum M. E., Wells C. G. Photocoagulation treatment of radiation retinopathy. Am J Ophthalmol. 1988 May 15;105(5):470–478. doi: 10.1016/0002-9394(88)90237-1. [DOI] [PubMed] [Google Scholar]
  8. Kinyoun J. L., Kalina R. E., Brower S. A., Mills R. P., Johnson R. H. Radiation retinopathy after orbital irradiation for Graves' ophthalmopathy. Arch Ophthalmol. 1984 Oct;102(10):1473–1476. doi: 10.1001/archopht.1984.01040031193016. [DOI] [PubMed] [Google Scholar]
  9. Kinyoun J., Barton F., Fisher M., Hubbard L., Aiello L., Ferris F., 3rd Detection of diabetic macular edema. Ophthalmoscopy versus photography--Early Treatment Diabetic Retinopathy Study Report Number 5. The ETDRS Research Group. Ophthalmology. 1989 Jun;96(6):746–751. doi: 10.1016/s0161-6420(89)32814-4. [DOI] [PubMed] [Google Scholar]
  10. Packer S., Stoller S., Lesser M. L., Mandel F. S., Finger P. T. Long-term results of iodine 125 irradiation of uveal melanoma. Ophthalmology. 1992 May;99(5):767–774. doi: 10.1016/s0161-6420(92)31899-8. [DOI] [PubMed] [Google Scholar]

Articles from The British Journal of Ophthalmology are provided here courtesy of BMJ Publishing Group

RESOURCES