Abstract
AIMS--A prospective randomised clinical trial was set up to compare the effect of hydroxypropyl methylcellulose (Ocucoat) and sodium hyaluronate (Healonid) on pupil size and reactivity following their use in cataract surgery. METHODS--Pupil measurements were recorded before and 6 weeks after surgery. RESULTS--There was no significant difference between the two groups with respect to pupil size (p = 0.69, Mann-Whitney U test) nor with respect to reactivity (p = 0.99, Fischer's exact test). Ninety six per cent of the surgery was performed using phacoemulsification. CONCLUSION--This trial suggests that both viscoelastic materials have similar effects on the pupil after their use in cataract surgery.
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Selected References
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- Aron-Rosa D., Cohn H. C., Aron J. J., Bouquety C. Methylcellulose instead of Healon in extracapsular surgery with intraocular lens implantation. Ophthalmology. 1983 Oct;90(10):1235–1238. doi: 10.1016/s0161-6420(83)34404-3. [DOI] [PubMed] [Google Scholar]
- Chumbley L. C., Morgan A. M., Musallam I. Hydroxypropyl methylcellulose in extracapsular cataract surgery with intraocular lens implantation: intraocular pressure and inflammatory response. Eye (Lond) 1990;4(Pt 1):121–126. doi: 10.1038/eye.1990.15. [DOI] [PubMed] [Google Scholar]
- Fechner P. U., Fechner M. U. Methylcellulose and lens implantation. Br J Ophthalmol. 1983 Apr;67(4):259–263. doi: 10.1136/bjo.67.4.259. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Rosen E. S., Gregory R. P., Barnett F. Is 2% hydroxypropylmethylcellulose a safe solution for intraoperative clinical applications? J Cataract Refract Surg. 1986 Nov;12(6):679–684. doi: 10.1016/s0886-3350(86)80087-6. [DOI] [PubMed] [Google Scholar]
- Sand B. B., Work K., Skovbo A., Elbøll P. Sodium hyaluronate and methylcellulose in extracapsular cataract extraction. A controlled study of the intraocular inflammation following the peroperative use of sodium hyaluronate and methylcellulose. Acta Ophthalmol (Copenh) 1991 Feb;69(1):65–67. doi: 10.1111/j.1755-3768.1991.tb01993.x. [DOI] [PubMed] [Google Scholar]
- Storr-Paulsen A., Larsen M. Long-term results of extracapsular cataract extraction with posterior chamber lens implantation: sodium hyaluronate 1% vs hydroxypropyl methylcellulose 2%. Acta Ophthalmol (Copenh) 1991 Dec;69(6):766–769. doi: 10.1111/j.1755-3768.1991.tb02057.x. [DOI] [PubMed] [Google Scholar]
- Tan A. K., Humphry R. C. The fixed dilated pupil after cataract surgery--is it related to intraocular use of hypromellose? Br J Ophthalmol. 1993 Oct;77(10):639–641. doi: 10.1136/bjo.77.10.639. [DOI] [PMC free article] [PubMed] [Google Scholar]
