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. 1995 Jul;79(7):649–652. doi: 10.1136/bjo.79.7.649

Is glaucoma associated with an increased risk of cataract?

E V Kuppens 1, J A van Best 1, C C Sterk 1
PMCID: PMC505191  PMID: 7662628

Abstract

AIMS--The risk of developing cataract in patients with untreated glaucoma or with ocular hypertension was evaluated by comparing the values of lenticular autofluorescence and light transmission in 16 patients with primary open angle glaucoma and 22 patients with ocular hypertension with those of 24 healthy controls. METHODS--Increase of lenticular autofluorescence and decrease of transmission values in comparison with controls were considered to be precursors of cataract. The values of both variables were determined by fluorophotometry. Each value was normalised for age by dividing it by the value for a healthy control of the same age. RESULTS--The mean age normalised autofluorescence and transmission values of all patients did not differ significantly from those of the controls (difference < 5%; p = 0.6 and p = 0.2, respectively). Also the mean age normalised autofluorescence and transmission values between glaucoma and ocular hypertension patients did not differ significantly (p = 0.8 and p = 0.9, respectively). CONCLUSION--The study indicates that untreated primary open angle glaucoma or untreated ocular hypertension do not seem to increase significantly the risk of developing cataract.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. Axelsson U., Holmberg A. The frequency of cataract after miotic therapy. Acta Ophthalmol (Copenh) 1966;44(3):421–429. doi: 10.1111/j.1755-3768.1966.tb08053.x. [DOI] [PubMed] [Google Scholar]
  2. Bleeker J. C., van Best J. A., Vrij L., van der Velde E. A., Oosterhuis J. A. Autofluorescence of the lens in diabetic and healthy subjects by fluorophotometry. Invest Ophthalmol Vis Sci. 1986 May;27(5):791–794. [PubMed] [Google Scholar]
  3. Boets E. P., Kok J. H., van Best J. A. The blue-green autofluorescence of the human ocular lens after the wear of PMMA contact lenses. Acta Ophthalmol (Copenh) 1994 Feb;72(1):67–71. doi: 10.1111/j.1755-3768.1994.tb02740.x. [DOI] [PubMed] [Google Scholar]
  4. Flanagan D. W. Diabetes, glaucoma, sex, and cataract. Br J Ophthalmol. 1993 Jan;77(1):1–1. doi: 10.1136/bjo.77.1.1. [DOI] [PMC free article] [PubMed] [Google Scholar]
  5. Greve E. L., Dake C. L., Klaver J. H., Mutsaerts E. M. Ten year prospective follow-up of a glaucoma operation. The Double Flap Scheie in primary open angle glaucoma. Int Ophthalmol. 1985 Sep;8(3):139–146. doi: 10.1007/BF00136490. [DOI] [PubMed] [Google Scholar]
  6. Harding J. J., Egerton M., van Heyningen R., Harding R. S. Diabetes, glaucoma, sex, and cataract: analysis of combined data from two case control studies. Br J Ophthalmol. 1993 Jan;77(1):2–6. doi: 10.1136/bjo.77.1.2. [DOI] [PMC free article] [PubMed] [Google Scholar]
  7. Harding J. J., Harding R. S., Egerton M. Risk factors for cataract in Oxfordshire: diabetes, peripheral neuropathy, myopia, glaucoma and diarrhoea. Acta Ophthalmol (Copenh) 1989 Oct;67(5):510–517. doi: 10.1111/j.1755-3768.1989.tb04101.x. [DOI] [PubMed] [Google Scholar]
  8. Laatkainen L. Late results of surgery on eyes with primary glaucoma and cataract. Acta Ophthalmol (Copenh) 1971;49(2):281–292. doi: 10.1111/j.1755-3768.1971.tb00952.x. [DOI] [PubMed] [Google Scholar]
  9. Mosier M. A., Occhipinti J. R., Burstein N. L. Autofluorescence of the crystalline lens in diabetes. Arch Ophthalmol. 1986 Sep;104(9):1340–1343. doi: 10.1001/archopht.1986.01050210094032. [DOI] [PubMed] [Google Scholar]
  10. Occhipinti J. R., Mosier M. A., Burstein N. L. Autofluorescence and light transmission in the aging crystalline lens. Ophthalmologica. 1986;192(4):203–209. doi: 10.1159/000309647. [DOI] [PubMed] [Google Scholar]
  11. Shaffer R. N., Rosenthal G. Comparison of cataract incidence in normal and glaucomatous population. Am J Ophthalmol. 1970 Mar;69(3):368–371. doi: 10.1016/0002-9394(70)92266-x. [DOI] [PubMed] [Google Scholar]
  12. Sugar H. S. Postoperative cataract in successfully filtering glaucomatous eyes. Am J Ophthalmol. 1970 May;69(5):740–746. doi: 10.1016/0002-9394(70)93414-8. [DOI] [PubMed] [Google Scholar]
  13. Van Buskirk E. M. Hazards of medical glaucoma therapy in the cataract patient. Ophthalmology. 1982 Mar;89(3):238–241. doi: 10.1016/s0161-6420(82)34811-3. [DOI] [PubMed] [Google Scholar]
  14. Watson P. G., Jakeman C., Ozturk M., Barnett M. F., Barnett F., Khaw K. T. The complications of trabeculectomy (a 20-year follow-up). Eye (Lond) 1990;4(Pt 3):425–438. doi: 10.1038/eye.1990.54. [DOI] [PubMed] [Google Scholar]
  15. Yappert M. C., Borchman D., Byrdwell W. C. Comparison of specific blue and green fluorescence in cataractous versus normal human lens fractions. Invest Ophthalmol Vis Sci. 1993 Mar;34(3):630–636. [PubMed] [Google Scholar]
  16. van Heyningen R., Harding J. J. A case-control study of cataract in Oxfordshire: some risk factors. Br J Ophthalmol. 1988 Nov;72(11):804–808. doi: 10.1136/bjo.72.11.804. [DOI] [PMC free article] [PubMed] [Google Scholar]
  17. van Wirdum E., Mota M. C., van Best J. A., Leite E., Kappelhof J. P., Faria de Abreu J. R., Paul L. C., Freitas Martins J., Oosterhuis J. A., Marques A. Lens transmission and autofluorescence in renal disease. Ophthalmic Res. 1988;20(5):317–326. doi: 10.1159/000266736. [DOI] [PubMed] [Google Scholar]

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