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. 1992 Oct;76(10):592–593. doi: 10.1136/bjo.76.10.592

Photodamage of the conjunctiva in patients with porphyria cutanea tarda.

H Hammer 1, I Korom 1
PMCID: PMC505226  PMID: 1358193

Abstract

Ninety two patients with porphyria cutanea tarda (PCT) were examined ophthalmically in a paired case control study. The incidence of pinguecula and of pterygium was 8 and 2 times higher respectively, in PCT patients than in the control group. The photodamage to the conjunctiva is considered to be a result of the photoactivity of uroporphyrin in the tissues.

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Selected References

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  1. BARNES H. D., BOSHOFF P. H. Ocular lesions in patients with porphyria. AMA Arch Ophthalmol. 1952 Nov;48(5):567–580. doi: 10.1001/archopht.1952.00920010578003. [DOI] [PubMed] [Google Scholar]
  2. Doss M. Analytical and preparative thin-layer chromatography of porphyrin methyl esters. Z Klin Chem Klin Biochem. 1970 May;8(3):197–207. doi: 10.1515/cclm.1970.8.3.197. [DOI] [PubMed] [Google Scholar]
  3. Douglas W. H. Congenital porphyria: general and ocular manifestations. Trans Ophthalmol Soc U K. 1972;92:541–553. [PubMed] [Google Scholar]
  4. Girod P. Les signes ophtalmologiques de la porphyrie congénitale. Ann Ocul (Paris) 1969 Sep;202(9):937–951. [PubMed] [Google Scholar]
  5. Lim H. W., Gigli I. Role of complement in porphyrin-induced photosensitivity. J Invest Dermatol. 1981 Jan;76(1):4–9. doi: 10.1111/1523-1747.ep12524423. [DOI] [PubMed] [Google Scholar]
  6. Lim H. W., Gigli I., Wasserman S. I. Differential effects of protoporphyrin and uroporphyrin on murine mast cells. J Invest Dermatol. 1987 Mar;88(3):281–286. doi: 10.1111/1523-1747.ep12466140. [DOI] [PubMed] [Google Scholar]
  7. Lim H. W. Pathophysiology of cutaneous lesions in porphyrias. Semin Hematol. 1989 Apr;26(2):114–119. [PubMed] [Google Scholar]
  8. MANTEL N., HAENSZEL W. Statistical aspects of the analysis of data from retrospective studies of disease. J Natl Cancer Inst. 1959 Apr;22(4):719–748. [PubMed] [Google Scholar]
  9. Melski J. W., Tanenbaum L., Parrish J. A., Fitzpatrick T. B., Bleich H. L. Oral methoxsalen photochemotherapy for the treatment of psoriasis: a cooperative clinical trial. J Invest Dermatol. 1977 Jun;68(6):328–335. doi: 10.1111/1523-1747.ep12496022. [DOI] [PubMed] [Google Scholar]
  10. Sevel D., Burger D. Ocular involvement in cutaneous porphyria. A clinical and histological report. Arch Ophthalmol. 1971 May;85(5):580–585. doi: 10.1001/archopht.1971.00990050582010. [DOI] [PubMed] [Google Scholar]
  11. TOPPEL L. VERAENDERUNGEN DES AUGENHINTERGRUNDES BEI PORPHYRIA CUTANEA TARDA. Munch Med Wochenschr. 1965 May 7;107:933–935. [PubMed] [Google Scholar]

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