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. 1995 Aug;79(8):732–734. doi: 10.1136/bjo.79.8.732

Comparison of flow velocity of ophthalmic artery between primary open angle glaucoma and normal tension glaucoma.

Y Yamazaki 1, F Hayamizu 1
PMCID: PMC505234  PMID: 7547783

Abstract

AIMS--This study describes an investigation of the relation between the change of intraocular circulatory dynamics and visual field defect between primary open angle glaucoma (POAG) and normal tension glaucoma (NTG). METHODS--The method was to determine the blood flow velocity of the ophthalmic artery using colour Doppler imaging and quantitative peak systolic flow velocity, mean envelope velocity, end diastolic velocity, and Pourcelot resistivity index (RI) were determined. The visual field was examined using program 30-2 of the Humphrey field analyser: the mean deviation (MD) and corrected pattern standard deviation (CPSD) were calculated as indices for visual field defects. There were 25 patients with POAG and 25 patients with NTG. RESULTS--There were no significant differences in all the four indices of the ophthalmic arterial flow and in both of visual field indices between patients with POAG and those with NTG. However, NTG patients alone showed a statistically significant correlation between RI and MD. CONCLUSION--The results suggest the vascular resistance of the ophthalmic artery may be associated with the development of visual field defect in NTG patients.

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Selected References

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  1. Anderson D. R. The management of elevated intraocular pressure with normal optic discs and visual fields. I. Therapeutic approach based on high risk factors. Surv Ophthalmol. 1977 May-Jun;21(6):479–489. doi: 10.1016/s0039-6257(77)80004-0. [DOI] [PubMed] [Google Scholar]
  2. Baxter G. M., Williamson T. H., McKillop G., Dutton G. N. Color Doppler ultrasound of orbital and optic nerve blood flow: effects of posture and timolol 0.5%. Invest Ophthalmol Vis Sci. 1992 Mar;33(3):604–610. [PubMed] [Google Scholar]
  3. Drance S. M., Douglas G. R., Wijsman K., Schulzer M., Britton R. J. Response of blood flow to warm and cold in normal and low-tension glaucoma patients. Am J Ophthalmol. 1988 Jan 15;105(1):35–39. doi: 10.1016/0002-9394(88)90118-3. [DOI] [PubMed] [Google Scholar]
  4. Flaharty P. M., Lieb W. E., Sergott R. C., Bosley T. M., Savino P. J. Color Doppler imaging. A new noninvasive technique to diagnose and monitor carotid cavernous sinus fistulas. Arch Ophthalmol. 1991 Apr;109(4):522–526. doi: 10.1001/archopht.1991.01080040090035. [DOI] [PubMed] [Google Scholar]
  5. Galassi F., Nuzzaci G., Sodi A., Casi P., Vielmo A. Color Doppler imaging in evaluation of optic nerve blood supply in normal and glaucomatous subjects. Int Ophthalmol. 1992 Sep;16(4-5):273–276. doi: 10.1007/BF00917974. [DOI] [PubMed] [Google Scholar]
  6. Gasser P., Flammer J. Influence of vasospasm on visual function. Doc Ophthalmol. 1987 May;66(1):3–18. doi: 10.1007/BF00144735. [DOI] [PubMed] [Google Scholar]
  7. Geijer C., Bill A. Effects of raised intraocular pressure on retinal, prelaminar, laminar, and retrolaminar optic nerve blood flow in monkeys. Invest Ophthalmol Vis Sci. 1979 Oct;18(10):1030–1042. [PubMed] [Google Scholar]
  8. Guthoff R. F., Berger R. W., Winkler P., Helmke K., Chumbley L. C. Doppler ultrasonography of the ophthalmic and central retinal vessels. Arch Ophthalmol. 1991 Apr;109(4):532–536. doi: 10.1001/archopht.1991.01080040100037. [DOI] [PubMed] [Google Scholar]
  9. Hayreh S. S. Blood supply of the optic nerve head and its role in optic atrophy, glaucoma, and oedema of the optic disc. Br J Ophthalmol. 1969 Nov;53(11):721–748. doi: 10.1136/bjo.53.11.721. [DOI] [PMC free article] [PubMed] [Google Scholar]
  10. Hayreh S. S. Inter-individual variation in blood supply of the optic nerve head. Its importance in various ischemic disorders of the optic nerve head, and glaucoma, low-tension glaucoma and allied disorders. Doc Ophthalmol. 1985 Apr 30;59(3):217–246. doi: 10.1007/BF00159262. [DOI] [PubMed] [Google Scholar]
  11. Ho A. C., Lieb W. E., Flaharty P. M., Sergott R. C., Brown G. C., Bosley T. M., Savino P. J. Color Doppler imaging of the ocular ischemic syndrome. Ophthalmology. 1992 Sep;99(9):1453–1462. doi: 10.1016/s0161-6420(92)31784-1. [DOI] [PubMed] [Google Scholar]
  12. Kitazawa Y., Shirato S., Yamamoto T. Optic disc hemorrhage in low-tension glaucoma. Ophthalmology. 1986 Jun;93(6):853–857. doi: 10.1016/s0161-6420(86)33658-3. [DOI] [PubMed] [Google Scholar]
  13. Lieb W. E., Cohen S. M., Merton D. A., Shields J. A., Mitchell D. G., Goldberg B. B. Color Doppler imaging of the eye and orbit. Technique and normal vascular anatomy. Arch Ophthalmol. 1991 Apr;109(4):527–531. doi: 10.1001/archopht.1991.01080040095036. [DOI] [PubMed] [Google Scholar]
  14. McLeod S. D., West S. K., Quigley H. A., Fozard J. L. A longitudinal study of the relationship between intraocular and blood pressures. Invest Ophthalmol Vis Sci. 1990 Nov;31(11):2361–2366. [PubMed] [Google Scholar]
  15. Phelps C. D., Corbett J. J. Migraine and low-tension glaucoma. A case-control study. Invest Ophthalmol Vis Sci. 1985 Aug;26(8):1105–1108. [PubMed] [Google Scholar]
  16. Quigley H. A., Addicks E. M., Green W. R., Maumenee A. E. Optic nerve damage in human glaucoma. II. The site of injury and susceptibility to damage. Arch Ophthalmol. 1981 Apr;99(4):635–649. doi: 10.1001/archopht.1981.03930010635009. [DOI] [PubMed] [Google Scholar]
  17. Quigley H. A., Hohman R. M., Sanchez R., Addicks E. M. Optic nerve head blood flow in chronic experimental glaucoma. Arch Ophthalmol. 1985 Jul;103(7):956–962. doi: 10.1001/archopht.1985.01050070082035. [DOI] [PubMed] [Google Scholar]
  18. Rojanapongpun P., Drance S. M., Morrison B. J. Ophthalmic artery flow velocity in glaucomatous and normal subjects. Br J Ophthalmol. 1993 Jan;77(1):25–29. doi: 10.1136/bjo.77.1.25. [DOI] [PMC free article] [PubMed] [Google Scholar]
  19. Sossi N., Anderson D. R. Effect of elevated intraocular pressure on blood flow. Occurrence in cat optic nerve head studied with iodoantipyrine I 125. Arch Ophthalmol. 1983 Jan;101(1):98–101. doi: 10.1001/archopht.1983.01040010100018. [DOI] [PubMed] [Google Scholar]
  20. Weinstein J. M., Duckrow R. B., Beard D., Brennan R. W. Regional optic nerve blood flow and its autoregulation. Invest Ophthalmol Vis Sci. 1983 Dec;24(12):1559–1565. [PubMed] [Google Scholar]
  21. Williamson T. H., Baxter G. M., Dutton G. N. Color Doppler velocimetry of the optic nerve head in arterial occlusion. Ophthalmology. 1993 Mar;100(3):312–317. doi: 10.1016/s0161-6420(93)31649-0. [DOI] [PubMed] [Google Scholar]

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