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. 2016 May 2;7(21):31336–31349. doi: 10.18632/oncotarget.9140

Figure 6. AMPK and TORC1 pathway were critical for regulating NUCB-2-mediated inhibition of migration and invasion.

Figure 6

(A) The effect of NUCB-2 suppression in AMPK and TORC1 pathways. (B) The effect of AMPK inhibitor. To determine the TORC1 and EMT pathways, protein was collected after 3 hours treatment and 24 hours treatment in NUCB-2 knockdowned stable clones respectively. (C) Treatment of AMPK inhibitor enhanced migration ability and (D) invasion ability of NUCB-2 knockdowned stable clones. Data represent mean ± SD. *p < 0.05; **p < 0.01; ***p < 0.001.