Table 2. Multivariate analysis of cancer specific survival, tissue collection.

Variables	Cancer specific survival		p
	HR	(95% confidence interval)
Age ≥ median (69 y)	1,85	(0.99-3,44)	0.053
Female vs. male	0,73	(0.363-1.461)	0.37
Rectal location	4,32	(2.06-9.04)	<0.01
T stage	3,93	(1.77-8.76)	<0.01
High tumor grade	1,37	(1.37-3.24)	0.47
CYB5R1 positive	8,51	(1.13-64.05)	0.038