Table 2.
Clinical Data for 24 patients undergoing ATL/AH and Temporal Cortical RNA Expression Analysis
| Subject Number | Seizure Focus | AED | MRI/CT | Extent Resection# (cm) |
|---|---|---|---|---|
| 1 | LMT* | P,V,S | MTS | 4.5 |
| 2 | RLT* | P,Z,L,LA,LAC,VI | TBI* | 5.5# |
| 3 | RT# | C,P,L,VI | MTS | 5.5# |
| 4 | RT# | C,O, Z, LA, VI | N | 5.5# |
| 5 | RT# | C, P, O, T, L, LA, LO |
N | 5.5# |
| 6 | RMT* | C, V, O, T, Z, L, Cl, LA, B, LO |
N | 5.5 # |
| 7 | LT# | P, L, LA, D, LO | MTS | 4.5 |
| 8 | RT# | O, L, LA | MTS | 5.5# |
| 9 | LRT* | P, G, Ph, VI, A | N | 4.5 |
| 10 | RT# | O, Z, L | MTS | 5.5# |
| 11 | RT# | L, LO, VI | HA | 5.5# |
| 12 | LT# | C, T, AC, Ci | MTS | 4.5 |
| 13 | LT# | P, O, T, L | MTS | 4.5 |
| 14 | RT# | P, V, T, LO | N | 5.5# |
| 15 | RT# | V, T, Z | MTS | 5.5# |
| 16 | RT# | C, P, V, O, T, Ph, L, TR, LY |
HA | 5.5# |
| 17 | RT# | O, Z, TR | MTS | 5.5# |
| 18 | RT# | C, P, O, L, TR | HA | 5.5# |
| 19 | LT# | LA, VI | MTS | 4.5 |
| 20 | LT# | P, L | CAV | 4.5 |
| 21 | RT# | C, P, Z, L | N | 5.5# |
| 22 | LT# | C, P, V, G, Z, LP | MTS | 4.5 |
| 23 | RLT* | C, L, LO | H | 5.5# |
| 24 | RT# | C | MTS | 5.5# |
Subject No. = Subject number in the study; Seizure Focus = Seizure Focus (first letter indicates lateraliaty: L = left, R = right, localization within temporal lobe indicated subsequently by: MT = medial temporal, LT = lateral temporal, RT = regional temporal lobe; RT= right temporal lobe, LT = left temporal lobe) localized by * = ictal subdural EEG recording or # = ictal scalp-EEG recording; AED = Anti-epileptic medication use pre-operatively (A = alprazolam, AC = acetazolamide, B = banzel, C = carbamaxepine, Ci = citalopram, Cl = clonazepam, D = diazepam, G = gabapentin, L = levetiracetam, LA = lamotrigine, LAC = lacosimide, LO = lorazepam, LP = loperamide, LY = lyrica, O = oxcarbazepine, P = phenytoin, Ph = phenobarbital, S = sabril, T = topiramate, TR = Trileptal, V = valproic acid, VI = vimpat, Z = zonisamide); MRI/CT = magnetic resonance imaging or computed tomography scan anatomic diagnosis pre-operatively, CT scan findings are indicated by “*” (MTS = medial temporal sclerosis, HA = hippocampal atrophy, CAV = cavernous malformation, N = normal temporal lobe anatomy, H = trigone heterotopia, TBI* = CT scan findings of traumatic brain injury), Extent Resection = extent of lateral temporal cortical resection in cm from anterior to posterior in the middle fossa, # = indicates a minimum of 5.5 cm anterior temporal lobectomy on the right side.