VOLUME 279 (2004) PAGES 38016–38024
There were several errors in this paper that the authors wish to correct. In the corrected Fig. 1, the panel showing the IGF1KO cells has been deleted because it appears to be an incorrect image. As Fig. 2 contains three example clones of IGFRKO cell differentiation, the presence of the IGFRKO panel in Fig. 1, which was not referred to under the “Results,” was redundant. We have also added dashed lines to indicate that the image was a composite of different tissue culture dishes. In the experiments shown in Fig. 6, A and B, the samples were loaded sequentially on the same gel, and the same basal sample served as 0 nm ligand for both insulin and IGF-1 stimulation. To create the double panel figures used in the paper, therefore, the basal sample lane was duplicated and spliced next to the IGF-1 stimulated samples. To clarify the confusion that this has created, a vertical white line has been added to the corrected Fig. 6 to all of the IGF-1 panels to indicate that the unstimulated lane to the left of the line has been spliced in and is the same unstimulated sample as appears in the insulin panels. The experiments in Fig. 7, B and C, were performed in the same fashion as those in Fig. 6. Therefore, the basal lanes shown in the IGF-1-stimulated panels are the same as the insulin-stimulated panels. For clarification, vertical white lines have been added to these figures to indicate the area of vertical splicing. None of these clarifications has any effect on the results of the study or their interpretation.
