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Surface rendered model of the overall topology of binding for D-DT and the CD74 trimerization domain. D-DT binds to CD74 in an angular way. a) CD74 trimer vertical axis contrasts with the D-DT axis tilted about 120°. b) Complex with the D-DT axis maintained in a vertical orientation. The CD74 receptor is in blue and the different D-DT subunits are in light grey, pink and yellow.
