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. Author manuscript; available in PMC: 2017 Jan 11.
Published in final edited form as: Biomacromolecules. 2015 Dec 11;17(1):154–164. doi: 10.1021/acs.biomac.5b01280

Table 1.

Exchange Parameters Obtained from Global Fitting Relaxation Data using eq. 1 (see main text) for H2/H6/H8 (6.6–9.0 ppm) and H5/H1′ (5.1–6.3 ppm). pfree = 1 − pbound where pbound is the fraction of RNA bound in the small-sized polyplexes in fast exchange with free RNA.

N:P pfree R2,polyplex (s−1) (H2/H6/H8) R2,polyplex (s−1) (H5/H1′)
0 1 311 ± 111 236 ± 84
0.25 0.97 ± 0.02
0.50 0.89 ± 0.06
1.0 0.64 ± 0.21