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Indian Journal of Hematology & Blood Transfusion logoLink to Indian Journal of Hematology & Blood Transfusion
. 2016 Jun 17;32(4):512–513. doi: 10.1007/s12288-016-0695-6

Strawberry Pink Blood

Jayashree D Kulkarni 1,, Puneeta Bhatia 2,3, Sanjay A Pai 2
PMCID: PMC5074977  PMID: 27812268

Abstract

Blood need not always be red. We report a case of a 3 month old boy whose blood was strawberry pink before centrifugation and white (profusely lipemic) after centrifugation. The differential diagnosis was familial hypercholesterolemia or familial combined hyperlipidemia.

Keywords: Colour, Hue


A 3 month old boy, born of a non-consanguineous marriage and detected to have hypercholesterolemia and hypertriglyceridemia elsewhere, was referred to our hospital. He had failure to thrive and hepatomegaly. Investigations revealed serum cholesterol of 890 mg/dl, (biological interval 114–203 mg/dl), serum ferritin of 8 ng/ml (50–200 ng/ml) and a hemoglobin of 10.3 g/dl (9.4–13 g/dl). The blood sample was profusely lipemic and appeared strawberry pink before centrifugation (image). Genetic testing and lipid fractions could not be performed. Our differential diagnosis was familial hypercholesterolemia (FH) or familial combined hyperlipidemia (FCHL).

FCHL is the most common primary lipid disorder and occurs in 1 in 200 people. It is an autosomal dominant condition with moderate elevation of triglycerides and LDL-cholesterol and reduced HDL-cholesterol. However, FH could be not ruled out because any person below 18 years with serum cholesterol of more than 270 mg/dl has an 88 % chance of having FH. FH is caused by a primary genetic defect in the LDL receptor gene which reduces LDL binding. Most patients have hypercholesterolemia at birth, increased plasma LDL and deposition of cholesterol in the skin, tendons and arteries.

A white serum sample after centrifugation is not uncommon but it is rare to see extraordinarily pink whole blood before centrifugation.graphic file with name 12288_2016_695_Figa_HTML.jpg

Compliance with Ethical Standards

Conflict of interest

Dr. Jayashree D. Kulkarni, Dr. Puneeta Bhatia, Dr. Sanjay A. Pai declares that she/he has no conflict of interest.

Ethical Approval

Institutional review board permission was taken. All procedures performed in studies involving human participants were in accordance with the ethical standards of the research committee and with the 1964 Helsinki declaration and its later amendments or comparable ethical standards.

Informed Consent

Not applicable.


Articles from Indian Journal of Hematology & Blood Transfusion are provided here courtesy of Springer

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