Table 3. Predicors of pCR in LARC patients receiving nCRT.
| Author | Study charactecistic | Pathologic complete response (pCR) | |||
|---|---|---|---|---|---|
| Type | N patient | Treatment | Rate (%) | Predictors (multivariate analysis) | |
| Das [15] | retrospective | 562 | nCRT + S | 19.2 | circumferential extent |
| Kalady [16] | retrospective | 242 | nCRT + S | 11.6 | time interval between nCRT and S |
| Park [17] | retrospective | 544 | nCRT + S | 12.9 | pre-nCRT T mobility, post-nCRT size, post-nCRT morphology |
| Garland [14] | retrospective | 297 | nCRT + S | 11.4 | T size, pre-nCRT N stage |
| Wallin [18] | retrospective | 469 | nCRT + S | 20.5 | CEA level, CHT interruption |
N: number; nCRT: neoadjuvant chemoradiotherapy; S: surgery; T: tumor; N: lmph nodes; CEA: carcino embryonic antigen; CHT: chemotherapy