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. 2016 May 13;7(23):33662–33674. doi: 10.18632/oncotarget.9358

Figure 3. Association of the risk allele G of rs700926 with decreased expression of NPR-C mRNA assuming a dominant model.

Figure 3

Because rs700926 is located near intron 1 of NPR-C, we hypothesized that it may affect the expression levels of the NPR-C mRNA. A. 5 individuals with a minor genotype of GG, 27 individuals with genotype GT and 63 individuals with genotype TT of rs700926 were selected for RT-PCR analysis. B. To validate the finding of a quantitative expression trait locus from the initial analysis, a replication study was also performed in an independent population of 380 randomly selected individuals from the replication populations (northern and southern Chinese).