Figure 2. Overexpression of SOX2 in i-SOX2-T3M4 cells reduces subcutaneous tumor growth.

Subcutaneous tumor volumes were determined for each group of 11 mice as described in the Materials and Methods. Average tumor volumes are presented for control and Dox-treated groups. Error bars represent standard error of the mean; statistical significance was determined by student's t-test (*p<0.05, ***p<0.005).