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. 2016 Sep 20;157(11):4257–4265. doi: 10.1210/en.2016-1571

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Figure 1. — Exogenous Cort treatment alters circulating Cort. A, Plasma Cort levels (nM) quantified at zeitgeber time (ZT1), 7 am and ZT13, 7 pm after 4 weeks of Cort treatment ($, Cort vs vehicle [V]; *, ZT13 vs ZT1; n = 5–6/treatment group). B, Adrenal and spleen mass after 4 weeks of treatment, ZT4 (unpaired t test; ***, P < .0001, n = 11–12/treatment group). C, Adrenal and spleen mass after 24 and 48 hours of treatment, ZT4 (unpaired t test; ***, P < .0001, n = 12/treatment group).