Table 2. List of MYCN-regulated microRNAs.

miRNA	Stem-loop sequence	Regulation of MYCN&	Number of target genes	3-node motif	4-node motif
miR-124-3p	mir-124-1 mir-124-3	R	2079	138*	296
miR-33a-5p	mir-33a	R	1212	51	214*
miR-1307-5p	mir-1307	R	0	0	0
miR-1268a	mir-1268a	R	31	1	1
miR-27a-3p	mir-27a	R	2264	115	303
miR-27b-3p	mir-27b	R	2307	115	308
miR-345-5p	mir-345	R	72	10*	7
miR-1268b	mir-1268b	R	8	0	0
miR-296-5p	mir-296	R	169	16*	31
miR-93-5p	mir-93	R	1916	130*	352*
miR-24-3p	mir-24-1 mir-24-2	R	1557	94*	365*
miR-25-3p	mir-25	R	1247	62	188
miR-181a-5p	mir-181a-1 mir-181a-2	A	1321	76*	307*
miR-330-3p	mir-330	A	689	45*	94
miR-320a	mir-320a	A	1204	74*	292*
miR-760	mir-760	A	250	14	22
miR-7-5p	mir-7-1 mir-7-2	A	1909	89	274
miR-181b-5p	hsa-mir-181b-1 hsa-mir-181b-2	A	1348	79*	316*
miR-2110	mir-2110	A	213	17*	30
miR-92b-5p	mir-92b	A	4	0	1
miR-181d-5p	mir-181d	A	1257	73*	286*
miR-887-3p	mir-887	A	8	0	2
miR-92a-1-5p	mir-92a-1	A	49	2	16
miR-1307-3p	mir-1307	A	2	0	0

^*denotes p-value < 0.05.

^&R: repression; A: activation.