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. 2016 Aug 25;8(8):1456–1466. doi: 10.1080/19420862.2016.1227901

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© 2016 The Author(s). Published with licensed by Taylor & Francis Group, LLC

This is an Open Access article distributed under the terms of the Creative Commons Attribution-Non-Commercial License (http://creativecommons.org/licenses/by-nc/3.0/), which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited. The moral rights of the named author(s) have been asserted.

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Figure 1. — Upstream process (USP) engineering flow diagram of the integrated process for monoclonal antibody (mAb) production at 300 kg/year capacity.