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. 2016 Aug 9;44(19):9518. doi: 10.1093/nar/gkw713

Long non-coding RNA INXS is a critical mediator of BCL-XS induced apoptosis

Carlos DeOcesano-Pereira 1, Murilo S Amaral 1, Kleber S Parreira 1, Ana C Ayupe 1, Jacqueline F Jacysyn 2, Gustavo P Amarante-Mendes 2,3, Eduardo M Reis 1,4, Sergio Verjovski-Almeida 1,4,*
PMCID: PMC5100591  PMID: 27507889

Nucl. Acids Res. (2014) 42 (13): 8343–8355. doi: 10.1093/nar/gku561

The authors of the above article wish to alert readers of an error in the experimental design to detect the relative abundance of the distinct BCL-X isoforms simultaneously with the induction of INXS. The authors did not notice that the primers used to detect the BCL-XL isoform by oligo-dT primed non-strand-specific RT-qPCR, as described in the Methods, were also detecting the endogenous or induced INXS transcript expressed in the opposite strand. This error affects Figures 4B, C, F, G, J, K, Figures 5B, C, F, G, J, K and Figures 6A, B, C, as well as Supplementary Figure S3, Figure S5B, Figures S6A, B, C, F, G, H, Figures S7A, B and Figures S8C, D. Although the authors consider that the errors do not materially affect the conclusions of the paper, they no longer have confidence in the detailed presentation of the data. Accordingly, the authors are retracting the full article.

The authors apologize for any inconvenience that this may have caused the scientific community and readers of the journal.

Supplementary Material

Supplementary Data

Supplementary Data are available at NAR Online.

SUPPLEMENTARY DATA

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Supplementary Materials

Supplementary Data

Supplementary Data are available at NAR Online.


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