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. Author manuscript; available in PMC: 2017 Jul 5.
Published in final edited form as: Oncogene. 2016 May 16;36(1):60–70. doi: 10.1038/onc.2016.175

Figure 4. Progression of DKO prostate tumorigenesis was inhibited in p27T187A/T187A mice.

Figure 4

(A) Representative H&E stained prostate sections of the indicated genotypes at the indicated ages. (B) Pathological diagnoses of prostate lesions as PIN of four stages, invasive carcinomas, and gross tumors. Numbers of mice examined in each age group are indicated below the chart. (C) Kaplan-Meier survival analysis comparing the p27+/+ and p27T187A/T187A cohorts of mice undergoing DKO prostate tumorigenesis. Hazard ratio = 2.514, 95% confidence interval = 2.077 to 6.222, p is by log-rank test.