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Oncology Reports logoLink to Oncology Reports
. 2016 Oct 19;36(6):3716. doi: 10.3892/or.2016.5181

Inhibitory effects of ethyl pyruvate administration on human gastric cancer growth via regulation of the HMGB1-RAGE and Akt pathways in vitro and in vivo

Jing Zhang, Jin-Shui Zhu, Zhou Zhou, Wei-Xiong Chen, Ni-Wei Chen
PMCID: PMC5112612  PMID: 27779688

Oncol Rep 27: 1511-1519, 2012; DOI: 10.3892/or.2012.1623

Following the publication of this article, an interested reader drew to the attention of the Editorial Board that the above article appeared to contain a series of Figures that featured duplicated data. Following an internal investigation, the Editorial Board reached the conclusion that the allegations of the reader were well-founded. Specifically, the GAPDH bands shown in Figs. 2 and 3 are identical with those in Figs. 4C and 5D, with the exception that the images have been reversed. Furthermore, certain data in Fig. 4C of this paper appeared to have been shared with Fig. 3 in the following article (albeit for purportedly different experiments): Zhang J, Zhu J, Zhou Z, Chen W and Chen N: Inhibitory effects of ethyl pyruvate on invasion and metastasis of human gastric cancer SGC-7901 cells via downregulation of Akt pathway. China J Cancer Prev Treat (Chin) 39: 776–779, 2012.

Despite numerous attempts at doing so, we were unable to receive any response to our request for further information from the authors of this article. Given the extent of the anomalies with the data between the aforementioned papers, the Editorial Board has therefore decided to retract the article from Oncology Reports. We regret any inconvenience in this regard.


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