Abstract
The renin-angiotensin-aldosterone system is now considered to be far more complex than previously thought when the vasoconstrictor and other physiological effects of the octapeptide angiotensin II in the circulating blood were emphasized. The reasons for this altered viewpoint, involving angiotensins other than the octapeptide in the regulation of blood pressure, water and electrolyte homeostasis, are briefly advanced and discussed.
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Contributor Information
Edward C. Osborn, Department of Renal Medicine, Southmead Hospital, Westbury-on-Trym, Bristol BS10 5NB
Andrew Davenport, Department of Renal Medicine, Southmead Hospital, Westbury-on-Trym, Bristol BS10 5NB.
Allen E. Goodship, Department of Anatomy, School of Veterinary Science, University of Bristol, Bristol BS1 5LS
J. Campbell Mackenzie, Department of Renal Medicine, Southmead Hospital, Westbury-on-Trym, Bristol BS10 5NB.