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. 2016 Nov 21;13:81. doi: 10.1186/s12977-016-0312-7

Table 1.

Representative neutralization data of JRFL and JRCSF pseudotyped viruses [3, 34, 38]

mAb epitope mAb JRFL JRCSF
CD4-bs b12 +++ ++
VRC01 +++ ++
NIH45-46 ++++ +++
CH103 ++++ +++
3BNC117 ++++ +++
8ANC131 +++ ++
CD4i 17b
V1V2V3 glycan-dependent PG9 ++++
PG16 ++++
PGT145 + ++++
PGT121 +++ +++
PGT128 ++++ ++++
2G12 + ++
MPER 10E8 ++ ++
4E10 + +
2F5 + +
FP VRC34 + ±

+ IC50: 1–10

++ IC50: 0.1–1

+++ IC50: 0.01–0.1

++++ IC50: <0.01

− IC50 > 50