Table 1.
mAb epitope | mAb | JRFL | JRCSF |
---|---|---|---|
CD4-bs | b12 | +++ | ++ |
VRC01 | +++ | ++ | |
NIH45-46 | ++++ | +++ | |
CH103 | ++++ | +++ | |
3BNC117 | ++++ | +++ | |
8ANC131 | +++ | ++ | |
CD4i | 17b | − | − |
V1V2V3 glycan-dependent | PG9 | − | ++++ |
PG16 | − | ++++ | |
PGT145 | + | ++++ | |
PGT121 | +++ | +++ | |
PGT128 | ++++ | ++++ | |
2G12 | + | ++ | |
MPER | 10E8 | ++ | ++ |
4E10 | + | + | |
2F5 | + | + | |
FP | VRC34 | + | ± |
+ IC50: 1–10
++ IC50: 0.1–1
+++ IC50: 0.01–0.1
++++ IC50: <0.01
− IC50 > 50